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memantine, etc. JohnX2

Posted by Elizabeth on October 28, 2001, at 10:53:47

In reply to Re: Lurker: Alert to Elizabeth, Opiate Proponents JeffH, posted by JohnX2 on October 27, 2001, at 11:27:14

> There is a medication
> called memantine, available in Europe, in clinical
> trials in us that can help prevent opiod addiction.

Memantine is an NMDA receptor antagonist. It may slow or prevent the development tolerance and dependence. I'm not clear that it prevents addiction, but the elimination of tolerance and dependence would solve many of the problems associated with addiction. Delta-opioid antagonists were also being looked at, last I heard. If anyone knows anything about these drugs, I'd be interested.

Methadone is merely a substitute, and while it is the best treatment available at this time (and I'm all in favor of harm reduction), it does have significant problems. (The implementation of MMT programs in the US is also problematic, of course.)

-elizabeth


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poster:Elizabeth thread:82364
URL: http://www.dr-bob.org/babble/20011025/msgs/82489.html