Psycho-Babble Medication | about biological treatments | Framed
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Re: Lamictal SLS

Posted by Emme on October 10, 2001, at 9:01:04

In reply to Re: Started Geodon, off Zyprexa--scott Emme, posted by SLS on October 5, 2001, at 23:32:29

Hi Scott,

Sorry for the long delay in response. I'm feeling too cruddy to even concentrate enough to post. But I really appreciate your input.

> Was your doctor convinced that this skin anomaly was indeed the appearance of the dangerous skin reaction?

She had me go immediately to a dermatologist who said it was a harmelss rash, but definitely a drug reaction. My doctor pulled me from the lamictal because she felt that a harmelss onset didn't guarantee a harmless outcome.

> If I were in your sneakers, I would be determined to try again, if you feel you have failed enough previous drug trials to justify it. You might ask your doctor to consult with someone that perhaps has had more experience seeing patients through the start-up period of Lamictal. He might be better able to assess whether the appearance of your skin discoloration is an absolute contraindication to continued treatment, or whether there are strategies to help establish a therapeutic dosage. If I have time, Ill see if I can come up with anything more specific.

Some form of rechallenge hasn't been ruled out. She's placed calls to experts to get their input. I think she's had a lot of patients on it, but I'm not sure she's had to really consider a rechallenge before. But we're getting to the point that it's a consideration.

> You might want to check out the work of Robert M. Post of the NIMH. I consider him among the top experts for treating refractory bipolar disorders bipolar depression and rapid-cyclicity, particularly. For rapid cyclers, he advocates the use of at least two mood stabilizers; usually lithium combined with Tegretol (or perhaps Trileptal, its sister drug), Depakote, or Lamictal. He has also had some success with the combination of Lamictal and Neurontin.

Okay, thanks. I will keep these things in mind.

> If anything comes to mind and stays there :-) - Ill let you know.

This is scary, but I've been glancing at the posts and I know you're trying something new, but I just can't remember what it is. (I'll look again when I get back to the screen with current posts.) But I wanted to say good luck and I hope it works for you. Sorry I'm so brain dead.





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