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Cheese Reaction Discovery Sunnely

Posted by Rick on August 18, 2001, at 17:27:26

In reply to Re: MAOI diet short list Rick, posted by Sunnely on August 17, 2001, at 23:15:33

> > My pdoc, who fancies himself a kind of MAOI historian, says that the knowledge of MAOI food interactions first came to light when Europeans taking them started inexplicably "dying", while this wasn't happening in the U.S. This pattern was eventually linked back to the inter-continental differences in dining habits, especially with regard to heavily-fermented beers and aged meats, cheeses, kraut, etc. thus uncovering the tyramine connection.
> If I am not mistaken, Barry Blackwell, M.D., retired Clinical Professor of Psychiatry, University of Wisconsin-Madison, was the one credited for discovering the "cheese reaction" with MAOIs.

Sunnely -

Interesting. Do you know roughly when Dr. Blackwell discovered the cheese reaction? (I know that MAOI antidepressant effect was uncovered in the mid fifties, but have no idea when they were first marketed as antidepressants.) My pdoc is a PhD who has been practicing since '78, and I seem to recall him telling me he was very involved with studies of MAOI's. I didn't see his name anywhere in Medline, but did a Google search and found (in a third-party site) that he has an huge and impressive curriculam vitae, including stints as president of the Chicago Psychiatric Association.
And apparently he *has* written many papers and some books on medical history, so I'd be surprised (but not amazed) if his story about the European connection was competely incorrect.

Especially given that Madison isn't very far from here, perhaps my pdoc knows Dr. Blackwell personally. I'll have to ask about that.

BTW, if I hadn't made some slightly snide remarks about him, I'd mention my pdoc's name and a few interesting tidbits I found in his Vitae.





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