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Re: Prozac Weekly?? SLS

Posted by Sunnely on May 13, 2001, at 14:02:30

In reply to Re: Prozac Weekly??, posted by SLS on May 13, 2001, at 11:02:51


In the recent annual APA meeting, Lilly reports that in an 8-week phase III study in patients with major depression who received 80 mg of duloxetine daily, patients experienced significantly greater improvement symptoms than those who used placebo or 20 mg of paroxetine.

Fifty of duloxetine-treated patients achieved remission of depression symptoms, versus 29.5% of patients receiving placebo. Lilly also reported on a phase II study that yielded similar results.

Duloxetine is a dual reuptake inhibitor of serotonin and norepinephrine.


> Hi Sunnely.
> > Lilly at the present time is already heavily investing their big bucks in what they hope is the next blockbuster antidepressant, duloxetine.
> Is that right? I thought that drug was abandoned a long time ago. I think it is a SNRI. When I first heard about it years ago, I was looking forward to seeing its development. However, my impression of duloxetine given by something I encountered on Medline awhile back is that it is not a very promising compound for treating depression.
> - Scott




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