Psycho-Babble Medication | about biological treatments | Framed
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Re: Scott

Posted by SLS on February 27, 2001, at 7:11:21

In reply to Scott, posted by katrina on February 26, 2001, at 16:05:58

> > You and I are in the same boat. I started taking Zyprexa about a week
ago and got some nice antidepressant effects early. I am also nervous
about it not continuing to work, as this has been my history. > > > >
Why did you increase your Zyprexa from 2.5mg to 5.0mg? > > How did you
feel at 2.5mg?

> > If Zyprexa does poop-out, you might want to consider Risperdal. I
have heard of people remaining well on it for a long time.

I thought increasing was the way to go but I have read that the low doses
were best. Any thought? I was thinking on doing a trial of a different
AP risperdal...but zyprexa is still ok...I just had such a great response
right away where all AD's had mostly failed. That first 4 days I felt
like I was freer, alert, more real energy, confident yet realistic of my
"issues" etc, and alive...Do ya know what I mean? It is still there
somewhat... Oh I even skied better-weird huh...Only gained 2lbs so far

At this time, I do not feel that the neuroleptic antipsychotic drugs
Zyprexa and Risperdal have therapeutic windows. I do not believe that they
lose their positive effects for treating depression at higher dosages. It
just seems that you can get away with smaller dosages than what is usually
prescribed for psychosis and schizoid symtoms. At some point there is an
optimum dosage beyond which one receives no further benefit but with an
increase in side effects. I get more from 5.0mg of Zyprexa than with
0.25mg. I got more from 2.0mg of Risperdal than with 1.0mg. I had to
discontinue Risperdal because of persistant cognitive side effects.
Unfortunately, neither of these drugs seem to have unlocked the door to my
dark room.

The neuroleptic that does seem to have a therapeutic window of sorts when
used for depression is amisulpride. Some people report doing better at
25mg or 50mg that they do at 100mg and higher.

With both Zyprexa and Risperdal, it can take a month or two before a solid
improvement is achieved.

I hope I was able to answer your question.

- Scott




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