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Re: Reboxetine onset of efficacy Q more..... JahL

Posted by Leonardo on November 1, 2000, at 10:53:56

In reply to Re: Reboxetine onset of efficacy Q more....., posted by JahL on October 27, 2000, at 16:15:38

> > I have taken reboxetine for more than a year in different combos with Paxil and mirtazapine (in the UK).
> >
> > Be aware that I had some bad side effects when starting up reboxetine too quickly, ie after the fisrt 4mg pill! Problems include intense irritability and violent outburts. I would recommend starting at 2mg for the first day and working up gradually. I've never taken more than 8mg per day, 4 or 6 usually does the trick for me, taken with paxil. The stimulation effect does wear off after a while though.
> >
> Hi Leonardo.
>
> Just wondering. What does Paxil/Remeron add to the Reboxetine? Is bad maths in evidence (sum > parts)? How good is the Rebox. alone and what doesn't it do for you?
>
> Thanx v much,
>
> Jah.

Sorry for the delay replying, I don't get on this group every day. By chance and random experimenting I found that rebox + paxil worked quite well for me. Rebox + remeron did very little.

For rebox + paxil, it was definitely the sum is more than the individual parts. I didn't get any noticeable antidepressant effect from either alone, but together I felt pretty good (mostly).

Reboxetine alone gave me a short term energy boost, and sometimes made me feel edgy or 'wired' as I think some people call it. At worst I became quite manic, irritable and sometimes aggressive. This was the only time in my life I have enjoyed shouting at shop assistants and the like when their service was poor, usually I'm too shy! However, this is not a desirable behaviour really, and I had to come off the rebox. Note this happened when I was slavishly taking 8mg per day when 4 would probably have been plenty for me. The paxil seems to control the manic/anxiety tenedencies of the rebox, while the rebox combats the lethargy I got from paxil. My steady dose was only 4mg rebox (2mg morning, 2mg midday) plus 5mg paxil (evening).

How are you getting on?

Leonardo


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