Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Experienced MAOI vets needed » Judy

Posted by Cam W. on October 20, 2000, at 19:35:48

In reply to Re: CAM W. / Ant-Rock Questions, posted by Judy on October 19, 2000, at 20:33:21

> I haven't visited this board for a long time but the last time I participated, Anthony mentioned a doctor from down South, I believe, who regularly prescribed the combination of Parnate and Selegiline with good results.
> Anthony: Did you ever consider that combination? Do you remember the doctor's name and might he be written up on the internet somewhere?
> Cam: What is your learned opinion of that combination? What's the worst case scenario.
> I ask because I unsuccessfully took Selegiline for about six months, weaned off and started Parnate this past spring. The first week I took Parnate, I felt wonderful, then the bubble burst and I've been in a limbo of not-quite-depressed but definitely anhedonic ever since. I've been told that the initial mania had nothing whatsoever to do with selegeline remaining in my system, but I still can't help wondering...

Judy - As a caveat I'd like to say that I have limited experience with MAOIs, as they are seldom used in the population of people that I fill prescriptions for (actually, I don't think that I even carry Parnate in the store). Others on this board have much more experience with MAOIs than I do.

At therapeutic doses (no more than 10mg/day) selegiline (Eldepryl™) is a selective, irreversible inhibitor of MAO-B. Parnate™ (tranylcypromine) is an irrevesible inhibitor of both MAO-A and MAO-B. Other than perhaps being able to use lower doses of each when given together, I can't think of any reason to do so (but again, I lack real-life experience with MAOIs). Maybe the southern doc has fewer problems with the "tyramine effect" with this combination; I don't know.

Hopefully someone else can shed light on your question - Cam




Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:Cam W. thread:46685