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Re: any experience/knowledge of augmenting MAOI's?? shellie

Posted by SLS on October 18, 2000, at 6:42:38

In reply to Re: any experience/knowledge of augmenting MAOI's?? SLS, posted by shellie on October 15, 2000, at 23:21:34

Dear Shellie,

I'm glad you have experienced an immediate boost with Nardil. This doesn't surprise me, as this has also been my experience a few times. Nardil and Parnate do other things in addition to inhibiting the enzyme monoamine-oxidase. I don't know exactly what Nardil does, but your boost certainly is not the result of inhibition of MAO. Whatever it does do is what contributes to how well Nardil works for you. The initial boost may not last, and you will have to wait until later to get the full effect. For now, enjoy it. Cut your grass. Cut my grass.

I am disappointed with the way I have been feeling over this last week. I was hoping to get more out of Parnate + desipramine this time. The last few days pretty much sucked. Yesterday, it was like I wasn't taking anything at all.

I really like my new doctor. I need more to become familiar with him than he does me. He has a different way of working that will require that I learn more patience. It's hard to be patient, though, when all you want to do is pull your hand from the flame. I can tell that he has some definite ideas as the direction he wants to go. I think I'll let him lead the way.

With Nardil, I have had a great deal of trouble when combining it with a tricyclic. Last time, I tried to combine it with imipramine, and could not stand up. No exaggeration. I needed someone to help me walk from room to room. If I had known this potential, I would have started Nardil much more slowly. I think it could have made a difference. SLOW - like maybe 30mg for two weeks, 45 for two weeks, etc. If you need to add Serzone, and know its potential to produce hypotension when combined with Nardil, you may want to try a similar strategy. It may take you three or four weeks to reach a therapeutic dosage, but you might be able to establish the Serzone without provoking the body into a reaction.

Hoping you don't need to...





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