Psycho-Babble Medication | about biological treatments | Framed
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Re: AndrewB, S.D., and JohnL

Posted by JohnL on October 17, 2000, at 5:44:59

In reply to Re: AndrewB, S.D., and JohnL, posted by Billb on October 16, 2000, at 20:10:54


I hear ya on the Provigil. Yuck.

I don't like the option of increasing the Paxil dose, but that's just me. Certainly it's a well supported option. I just tend to feel if a medication isn't doing the job at a lower dose, then it's missing the mark anyway.

If Clono is working well, I would certainly do whatever is needed to convince your doctor to continue with it. As long as you stay at lower doses, longterm dependence should be minimal. The thing to watch out for is developing tolerance to it, where you find you need higher and higher doses over time. That's not good, and in my mind would warrant either staying at lower doses or discontinuing altogether. Becoming addicted at higher doses could cause way more problems than you ever had to begin with.

Certainly 25mg to 100mg of Amisulpride could be added. I don't see any prob with that at all. I've taken Amisulpride with all sorts of things, including a small dose of Prozac at the moment. If I had to rate meds as most effective, Amisulpride would be on the list. If I had to rate meds by tameness, it would be on that list too. Because it mainly affects just D2 dopamine receptors, it has little interaction with the mechanisms of other meds, and has a near absence of any side effects.

You could definitely consider Adrafinil as well. It's funny, Adrafinil and Provigil look practically identical in molecular diagrams. But they are in reality two completely different and two totally unrelated meds. I do very well with Adrafinil, and did very poorly with Provigil. They are totally different, even though they are supposedly similar. Not similar at all.

The best I've found for apathetic depression and for social anxiety is the combo of Amisulpride+Adrafinil. Either alone is very good, but the two together are really special. At least for me anyway. The things I like best about either of these meds is that they are far tamer than the meds our doctors give us, and yet far more effective. That never ceases to amaze me. Paxil for example is a heavy duty med compared to Adrafinil or Amisulpride, and yet either of the latter work so much better than Paxil for me. And yet they seem almost as tame as vitamins.




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