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Re: any experience/knowledge of augmenting MAOI's?? » JohnM

Posted by shellie on October 15, 2000, at 15:45:18

In reply to any experience/knowledge of augmenting MAOI's??, posted by JohnM on October 15, 2000, at 14:55:39

> I presently take Nardil. It worked well for me years ago, but not so much lately. Any input would be appreciated. John

John, I wrote the following post a couple of months ago to someone else who answered the same question, so I thought I'd copy it here for you:

>I'm going to give you all the information that I gathered since January, when I felt the nardil lost effectiveness, since some part of it may be helpful to you. I'll try to condense.

In Feb did a trial of sam-e with Nardil, with on the phone supervision with a physician affiliated with Columbia U. who wrote a book on sam-e. He gave sam-e a 70% change of working. Unfortunately, it was not good for me--it made me more depressed and very agitated. But if you look at the sam-e board at a lot of people who had tried lots of prescription meds, had enormous success with it.

He also said if the sam-e didn't work, these would be his recommendations to try with nardil:

1. thyroid, add 25 mc of cytomel (t3) for 2 weeks; can try 37.5 also
***2. lamcital- (anti-seizure medication) have to go up very very slowly„over a 3 month period--
3. add very low lithium level (works 50% of time)„
4. add traxedone (deserel)
5. add pindolol
6. add ridlin or dexadrine or adderall

Because my pdoc was unwilling to experiment, I also consulted with a pdoc at NIMH by phone (very helpful) and with my old pdoc, who was no longer
accepting my insurance.

The first choice of all three was lamictal. In the last" MAOI doesn't work anymore" thread, I explained that lamictal worked for me really well, but I was gaining weight. A very small percent of people gain weight on lamictal. I was unlucky and unwilling to accept a weight gain since there were other things for me to try. But I think it is very significant that all three doctors I consulted with, picked that as their first choice. >

Anyway, since that post I've tried the following augmentors with nardil (all unsuccessfully)
stimulents: ritalin, dexadrine
resperadone speech slurred)
amisulpride french anti-psychotic
adrafinil (french stimulent-had seratone reaction with combination--I don't recommend).

After getting off of nardil and trying serzone, I am now back on nardil and am adding some serzone. If I were you, my first choice would be lamictal, since it was recommended for me to try independently by three different doctors and it worked. (And very few people gain weight on it). Or deseral.

Good luck, hope I didn't overwhelm you. Shellie




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