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Q. for CAM W. re risperdal vs. zyprexa

Posted by anita on October 13, 2000, at 23:00:20

Hi Cam,

Some time ago you wrote a post about how risperidone may affect right-brain dysfunction, and zyprexa left-brain dysfunction. Do you know what this means exactly in terms of depression?

I'd like to try adding on a small dose of one of the new antipsychotics (to zoloft and lamictal), theoretically for the 5HT2A antagonism. From what I've read, it seems that while risperidone has a higher affinity for 5HT2A, zyprexa actually tends to be more helpful for depression. Also, I've read that seroquel is not a good add-on for depression. Can you tell me what you think about this? My unresolved depressive symptoms are primarily apathy, social phobia, and lack of willpower/motivation.

thanks a lot,




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