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Re: Info on oxcarbazepine - Thanks! medlib

Posted by Chris A. on July 27, 2000, at 23:49:27

In reply to Re: Info on oxcarbazepine - Scott, Cam, anyone??, posted by medlib on July 27, 2000, at 18:23:15

> did you find reference to cognitive enhancement for this drug?

One UK study, (Eur J Clin Pharmocol 1993;44(6):529-33), which appeared to have face validity, indicated that OXCZ improved performance (compared to placebo) on a focused attention task and increased manual writing. Subjective ratings showed that it increased feelings of alertness, clear headedness and quickwittedness. The researchers concluded that it has a slightly stimulant effect on some aspects of psychomotor functioning.

Another Brazilian study suggested a potential AD effect. (Eur J Pharmacol 1998 Apr 17;347(1):23-7).

>I ask because the drug lit mentions cognitive difficulties (I presume, similar to Tegretol).

I'm praying that the results of the above studies apply to me! We're jumping through all sorts of hoops to try to enhance and perserve cognitive functioning. My neurons have had enough and feel like they're about 1,000 years old.

> Anyway, hope this helps a little,

Yes, this does help. Thanks a bunch. Following a lot of ECT I've found I've had to relearn lots of details, and one of them is how to search. My therapist showed me where the control is for the emergency flashers is on my car yesterday. I've been driving around for six months without a clue. Talk about feeling dumb!

How are < you > doing??


Chris A.




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