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Re: Effexor Wellbutrin combination

Posted by JohnL on July 10, 1999, at 7:10:53

In reply to Effexor Wellbutrin combination, posted by Peter on July 9, 1999, at 20:36:06

> My doc just started me on effexor xr 150 mg/day 2 weeks ago, so far I do feel just a tiny bit better. He also prescribed Wellbutrin SR 100 mg as a boost which I haven't started taking. Does anyone have experience with this combination? Apparently there is literature that says that these two drugs act synergistically. Any info would be most appreciated. Thanks! Peter

Wellbutrin is synergistic with a lot of drugs and is a common add-on. It rounds out the therapeutic scope by working on NE and dopamine, not much on serotonin. It is generally an activating drug, not sedating. It is known to cause weight loss in many people but also boosts sex drive. Of course, we're all different. Your mileage may vary. I tried it with Remeron, and each of the SSRIs in my travels, but it always causes severe tinnitus for me. That's too bad, because I liked the way it picked me up. Hope you like it and all goes well. By the way, it is also marketed as Zyban to quit smoking. In that situation 200mg (100 twice a day) is the starting dose. If 100mg helps, great. But there is plenty of upside potential if it doesn't. Like any antidepressant though, give it time to work. Two weeks isn't very long for any drug. Persistence should pay off. Wishing you the very best. JohnL.




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