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Re: which antidepressant is best for GAD?

Posted by John on August 31, 1998, at 8:09:43

In reply to which antidepressant is best for GAD?, posted by Bill on July 17, 1998, at 13:51:24

> I have read some antidepressants are better than others for GAD? Is Remeron one of these?

Remeron (mirtazapine) appears to have an anxiolytic effect, similar to benzodiazepines. Further, it is a new class of anti-depressants, offering both a serotonergic and noradrenergic effect. It also antogonizes the 5HT1 receptor (which is the receptor targeted by buspirone). It is also one of the few anti-depressants without a sexual side effect. However, some patients seem to have problems with weight gain, as well as somnolence (sleepiness). Some of this can be managed by taking the medication at night (it's once a day dosing).

Bottom line: might be worth a try, as Buspirone seems to have a somewhat equivacal effect, and Remeron may eliminate the need for Benzodiazepine.




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