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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by Lamdage22 on September 24, 2021, at 15:15:47
Im taking a glutamine enriched protein powder and feeling pretty decent. https://pubmed.ncbi.nlm.nih.gov/30266598/
What does science say?
Posted by Jay2112 on September 24, 2021, at 18:37:03
In reply to Glutamine, posted by Lamdage22 on September 24, 2021, at 15:15:47
> Im taking a glutamine enriched protein powder and feeling pretty decent. https://pubmed.ncbi.nlm.nih.gov/30266598/
>
> What does science say?Hmmm..well, I am an Adult Educator, no real hard science. But, I think you should be careful with Glutamate. Glutamate, or l-glutamate, are precursor's to NMDA, and mood stabilizers and other's are NMDA antagonists.
Just IMHO, YMMV, etc..
Jay
Posted by sigismund on September 24, 2021, at 21:38:49
In reply to Re: Glutamine, posted by Jay2112 on September 24, 2021, at 18:37:03
Sometimes it converts into glutamate, sometimes into GABA. Does that depend on mineral cofactors?
Posted by Lamdage22 on September 25, 2021, at 0:27:37
In reply to Re: Glutamine, posted by sigismund on September 24, 2021, at 21:38:49
Ok. Isnt there a glutamate hypofunction hypothesis of schizophrenia? My issues have a tendency towards that diagnosis. I do take Neuroleptics.
Posted by undopaminergic on September 25, 2021, at 0:32:05
In reply to Re: Glutamine, posted by Lamdage22 on September 25, 2021, at 0:27:37
> Ok. Isnt there a glutamate hypofunction hypothesis of schizophrenia?
Yes, it is the most modern hypothesis.
-undopaminergic
Posted by undopaminergic on September 25, 2021, at 0:34:35
In reply to Re: Glutamine, posted by Jay2112 on September 24, 2021, at 18:37:03
> > Im taking a glutamine enriched protein powder and feeling pretty decent. https://pubmed.ncbi.nlm.nih.gov/30266598/
> >
> > What does science say?
>
> Hmmm..well, I am an Adult Educator, no real hard science. But, I think you should be careful with Glutamate. Glutamate, or l-glutamate, are precursor's to NMDA, and mood stabilizers and other's are NMDA antagonists.
>Glutamine is a precursor to glutamate and GABA. NMDA does not occur naturally in the body.
Memantine is a NMDA-glutamate antagonist, and can cause mania.
-undopaminergic
Posted by sigismund on September 25, 2021, at 1:51:48
In reply to Re: Glutamine, posted by undopaminergic on September 25, 2021, at 0:34:35
Excitotoxicity used to be discussed more. That's to do with this?
Posted by undopaminergic on September 25, 2021, at 5:10:12
In reply to Re: Glutamine, posted by sigismund on September 25, 2021, at 1:51:48
> Excitotoxicity used to be discussed more. That's to do with this?
A certain degree of excess agonism at glutamate receptors is excitotoxic.
I said NMDA does not occur naturally in the body, but the Wikipedia article claims it functions as a neurotransmitter:
https://en.wikipedia.org/wiki/N-Methyl-D-aspartic_acid-undopaminergic
This is the end of the thread.
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