Psycho-Babble Medication Thread 1113728

Shown: posts 1 to 21 of 21. This is the beginning of the thread.

 

Ketamine infusion

Posted by mogger on February 13, 2021, at 21:41:24

I am surprised I havent seen more posts regarding ketamine. Specifically I have had four infusions and can definitively say after the fourth treatment my depression was twice as bad if not more than when I started. I can only surmise that added glutamate is not what I need. An awful experience for me but of course I hope others the opposite.

 

Re: Ketamine infusion

Posted by Lamdage22 on February 14, 2021, at 4:26:49

In reply to Ketamine infusion, posted by mogger on February 13, 2021, at 21:41:24

I have never heard that, but I too sometimes get worse by things that are supposed to make people better. I refrain from Ketamine because I am vulnerable for psychosis.

 

Re: Ketamine infusion » Lamdage22

Posted by mogger on February 14, 2021, at 10:45:52

In reply to Re: Ketamine infusion, posted by Lamdage22 on February 14, 2021, at 4:26:49

I am shocked too as I thought it would be a guaranteed ticket to feeling better. So frustrating.

 

Re: Ketamine infusion » mogger

Posted by beckett2 on February 14, 2021, at 16:58:41

In reply to Ketamine infusion, posted by mogger on February 13, 2021, at 21:41:24

Ketamine doesn't increase or enhance glutamate, does it? I thought it was the opposite.

 

Re: Ketamine infusion » mogger

Posted by beckett2 on February 14, 2021, at 16:59:29

In reply to Ketamine infusion, posted by mogger on February 13, 2021, at 21:41:24

> I am surprised I havent seen more posts regarding ketamine. Specifically I have had four infusions and can definitively say after the fourth treatment my depression was twice as bad if not more than when I started. I can only surmise that added glutamate is not what I need. An awful experience for me but of course I hope others the opposite.

Btw, I'm sorry you had this outcome :(

 

Re: Ketamine infusion » beckett2

Posted by mogger on February 14, 2021, at 18:16:36

In reply to Re: Ketamine infusion » mogger, posted by beckett2 on February 14, 2021, at 16:58:41

It increases glutamate big time but is also an nmda antagonist.

 

Re: Ketamine infusion » mogger

Posted by beckett2 on February 14, 2021, at 18:20:51

In reply to Re: Ketamine infusion » beckett2, posted by mogger on February 14, 2021, at 18:16:36

> It increases glutamate big time but is also an nmda antagonist.

So weird (and interesting) bc I thought (obviously incorrectly) that excess glutamate is implicated in chronic pain (which I have) and I did very well w a transfusion, which helped my mood and my pain level.

So now you know it does not work for you. Have you tried a medication that affects glutamate in an 'opposite' way? Maybe through a psychopharmacologist.

 

Re: Ketamine infusion

Posted by Lamdage22 on February 15, 2021, at 0:08:02

In reply to Re: Ketamine infusion » Lamdage22, posted by mogger on February 14, 2021, at 10:45:52

When I was in hospital, they claimed that 70% respond.

> I am shocked too as I thought it would be a guaranteed ticket to feeling better. So frustrating.

 

Re: Ketamine infusion » Lamdage22

Posted by mogger on February 15, 2021, at 8:21:14

In reply to Re: Ketamine infusion, posted by Lamdage22 on February 15, 2021, at 0:08:02

I am a true non responder in every sense!

 

Re: Ketamine infusion

Posted by Lamdage22 on February 15, 2021, at 8:31:51

In reply to Re: Ketamine infusion » Lamdage22, posted by mogger on February 15, 2021, at 8:21:14

Well, it was a negative response. I hate those. I always ask myself if i wil return back to my old normal or if the negative changes will stick.

> I am a true non responder in every sense!

 

Re: Ketamine infusion

Posted by linkadge on February 15, 2021, at 9:26:36

In reply to Re: Ketamine infusion » mogger, posted by beckett2 on February 14, 2021, at 16:58:41

>Ketamine doesn't increase or enhance glutamate, >does it? I thought it was the opposite.

The actions are complex (some enhancement and some inhibition).

Linkadge

 

Re: Ketamine infusion » linkadge

Posted by mogger on February 15, 2021, at 14:56:38

In reply to Re: Ketamine infusion, posted by linkadge on February 15, 2021, at 9:26:36

Felt like enhancement and I dont do well with glutamate

 

Re: Ketamine infusion

Posted by undopaminergic on February 16, 2021, at 2:39:28

In reply to Re: Ketamine infusion » linkadge, posted by mogger on February 15, 2021, at 14:56:38

> Felt like enhancement and I dont do well with glutamate

How did you know what enhancement feels like?

-undopaminergic

 

Re: Ketamine infusion » mogger

Posted by alchemy on February 16, 2021, at 21:14:42

In reply to Re: Ketamine infusion » Lamdage22, posted by mogger on February 15, 2021, at 8:21:14

> I am a true non responder in every sense!

me too :( sorry for your struggle. glad i'm not alone.
i just tried a week of microdosing and i think it made me worse.
i've explored all avenues.

 

Re: Ketamine infusion » undopaminergic

Posted by mogger on February 16, 2021, at 21:50:47

In reply to Re: Ketamine infusion, posted by undopaminergic on February 16, 2021, at 2:39:28

Its like a wired too bright rush of depression and anxiety that comes in waves. Totally the opposite of relaxed and uplifting.

 

Re: Ketamine infusion » alchemy

Posted by mogger on February 16, 2021, at 21:53:15

In reply to Re: Ketamine infusion » mogger, posted by alchemy on February 16, 2021, at 21:14:42

I did microdosing too and it was awful. Made me worse. So sorry about your situation.

 

Re: Ketamine infusion

Posted by undopaminergic on February 17, 2021, at 3:20:52

In reply to Re: Ketamine infusion » undopaminergic, posted by mogger on February 16, 2021, at 21:50:47

> Its like a wired too bright rush of depression and anxiety that comes in waves. Totally the opposite of relaxed and uplifting.
>

Yes, but how do you know it has to do with excess glutamate?

-undopaminergic

 

Re: Ketamine infusion » undopaminergic

Posted by mogger on February 17, 2021, at 8:09:05

In reply to Re: Ketamine infusion, posted by undopaminergic on February 17, 2021, at 3:20:52

Identical feeling when I took high dose of glutamine.

 

Re: Ketamine infusion

Posted by Patrick35660 on February 23, 2021, at 22:14:02

In reply to Ketamine infusion, posted by mogger on February 13, 2021, at 21:41:24

Ketamine infusions didnt work well for me either after 6 months. I did really well for those 6 months (I thought) after taking an initial 12 infusions with 2 boosters. I crashed and took 9 more infusions hoping to get back to where I was for those 6 months and my anxiety and depression are worse now than they were before I took the treatments. I wish the best for you - the clinic I went to didnt mention anything about previous bouts with psychosis on my intake forms that I remember but Ive seen articles since I took the treatments that say it can make psychosis worse and I was diagnosed with a psychotic break in 2001. Spent a whole lot of money to get worse!

 

Re: Ketamine infusion » Patrick35660

Posted by mogger on February 23, 2021, at 23:15:51

In reply to Re: Ketamine infusion, posted by Patrick35660 on February 23, 2021, at 22:14:02

I am so sorry to hear this what a nightmare. It certainly aggravated my situation a huge amount. I cut off after four as I was heading down hill quickly. The fourth treatments disassociation was awful. I believe it will wear off for you in time. Hang in there.

 

Re: Ketamine infusion

Posted by Lamdage22 on February 24, 2021, at 5:33:34

In reply to Re: Ketamine infusion, posted by Patrick35660 on February 23, 2021, at 22:14:02

!!!! Thanks for sharing here. It is important to do so!

>and my anxiety and depression are worse now than they were before I took the treatments. I wish the best for you - the clinic I went to didnt mention anything about previous bouts with psychosis on my intake forms that I remember but Ive seen articles since I took the treatments that say it can make psychosis worse and I was diagnosed with a psychotic break in 2001. Spent a whole lot of money to get worse!


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