Psycho-Babble Medication Thread 1113301

Shown: posts 1 to 13 of 13. This is the beginning of the thread.

 

Anyone concerned about Dementia??

Posted by jay2112 on January 9, 2021, at 22:31:26

When Robin Williams committed suicide, the autopsy found massive decay, lewy body dementia. They were surprised he could even still walk!! My inability to just even sometimes make it through a day of doing *nothing* scares me. I am 51, I *want* it to get better...I don't do or threaten self-injury because I am GOING to get what I want. It's just certain drugs are not on my insurance formulary, and I can't afford to pay for them out-of-pocket. (I am in Canada...no public pharmacare).

What brain antioxidant is the most powerful and best??

Jay

 

Re: Anyone concerned about Dementia??

Posted by Lamdage22 on January 9, 2021, at 22:47:42

In reply to Anyone concerned about Dementia??, posted by jay2112 on January 9, 2021, at 22:31:26

Possibly Glutathione followed by VItamin E. I am having GSH checked soon. If it is low I am going to take S-Acetyl-GLutatione

 

Re: Anyone concerned about Dementia??

Posted by Lamdage22 on January 10, 2021, at 0:24:48

In reply to Re: Anyone concerned about Dementia??, posted by Lamdage22 on January 9, 2021, at 22:47:42

I am concerned, yeah. Neuroleptics don't help with that!

 

Re: Anyone concerned about Dementia??

Posted by Lamdage22 on January 10, 2021, at 1:13:35

In reply to Re: Anyone concerned about Dementia??, posted by Lamdage22 on January 10, 2021, at 0:24:48

Thats what I am talking about. Dementia, Tardive Dyskinesia. If you get either one, would you still consider the meds that helpful, even if they are "effective"?

 

Re: Anyone concerned about Dementia?? Lamdage22

Posted by jay2112 on January 10, 2021, at 14:58:46

In reply to Re: Anyone concerned about Dementia??, posted by Lamdage22 on January 10, 2021, at 1:13:35

> Thats what I am talking about. Dementia, Tardive Dyskinesia. If you get either one, would you still consider the meds that helpful, even if they are "effective"?

Well, I DO have a slight amount of TD. My left hand shakes quite badly, when put under a bit of strain, sometimes. Other times, I just notice is mildly.

I think maybe when I took Prozac, it contributed to it, as well as when I was on Risperdal. But I have been on every typical antipsychotic, and a few typicals (for brief periods of time) since.
Knock on wood, TD hasn't been much of a problem.

How about you, Lamdage22?

Jay

 

Re: Anyone concerned about Dementia-Benzos

Posted by jay2112 on January 10, 2021, at 15:21:46

In reply to Re: Anyone concerned about Dementia??, posted by Lamdage22 on January 10, 2021, at 0:24:48

I guess I am concerned more with my benzo use. (Which is only occasionally)..but I have to take higher doses than prescribed, because over 30 years, I have developed tolerance. Rxlist.com suggests that doses as high as 4mg a day may be needed. I am prescribed 3mg a day, and will save them up to take 6mg in one shot, along with Inderal, if I am having a rough day. This IS NOT abuse..I don't take them for recreational purposes, but as part of my BP2/GAD diagnosis.

But, since greatly reducing my Effexor/antidepressant use, my memory has much improved. I think AD's are much more detrimental to good cognitive functioning. As a BP2'er, ad's, at high doses, even medium, impair my memory, cognition, and temperament. Combined with ad's, benzos greatly impair my memory. Lower my ad, and I better tolerate benzos. I think there may be a secret to very low dose ad's. I remember a time when I was on imipramine, at 10-20mg's and I did great! But, the doctor kept pushing for higher doses.

Anyhow, I am a bit afraid to take those tests for either Lewis Body or Alzheimer's disease/dementia.

Jay

 

Re: Anyone concerned about Dementia??

Posted by Lamdage22 on January 10, 2021, at 22:13:02

In reply to Re: Anyone concerned about Dementia?? Lamdage22, posted by jay2112 on January 10, 2021, at 14:58:46

My tongue is shaky and moves a bit when i stick it out. But it has been like this for years, it doesn't get worse.

> How about you, Lamdage22?
>
> Jay
>

 

Re: Anyone concerned about Dementia??

Posted by Petermartin on January 12, 2021, at 23:35:52

In reply to Anyone concerned about Dementia??, posted by jay2112 on January 9, 2021, at 22:31:26

Very low dose Lithium (like microcodes that maybe should naturally exist in water) have been shown to help prevent cognitive decline.

https://www.medicalnewstoday.com/articles/can-lithium-halt-progression-of-alzheimers-disease

But yea, I'm a little concerned when it comes to mind.

 

Re: Anyone concerned about Dementia??

Posted by Hugh on January 13, 2021, at 11:37:00

In reply to Anyone concerned about Dementia??, posted by jay2112 on January 9, 2021, at 22:31:26

> What brain antioxidant is the most powerful and best??

https://www.lifeextension.com/magazine/2020/ss/fisetin-a-senolytic-for-longevity

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649683/

https://www.lifeextension.com/magazine/2007/10/report_curcumin

Petermartin's suggestion about microdosing lithium is a good one.

https://www.nytimes.com/2014/09/14/opinion/sunday/should-we-all-take-a-bit-of-lithium.html

Hope on the horizon:

https://medicalxpress.com/news/2021-01-hydrogen-sulfide-alzheimer-disease.html

 

Re: Anyone concerned about Dementia-Benzos

Posted by SLS on January 19, 2021, at 21:18:42

In reply to Re: Anyone concerned about Dementia-Benzos, posted by jay2112 on January 10, 2021, at 15:21:46

I read a recent article that reports that neither benzodiazepines nor the Z-drugs increase one's risk for developing Alzheimer's Dementia. However, anticholinergics do.


- Scott

 

Re: Anyone concerned about Dementia??

Posted by SLS on January 19, 2021, at 21:45:21

In reply to Re: Anyone concerned about Dementia??, posted by Hugh on January 13, 2021, at 11:37:00

Low-dosage lithium (300mg/day) improved my depression immediately, although not robustly, when it was added to Parnate. However, it consistently makes me feel worse at 450 mg/day or higher. For me, the dose-response curve is biphasic. It turns out that lithium's effect on glutamatergic activity also follows a biphasic curve. Low dosages increase glutamatergic activity while high dosages decrease it. Anyway, when it was unclear whether or not lithium was still having a positive effect on my mood, I elected to continue taking it regardless. The *only* reason why I continued to take lithium was because I had read about it possibly preventing Alzheimer's Dementia. I can't remember how many years I've been taking low-dosage lithium for. It has been at least 10 years.

At this point, my personal experience with lithium and at least one Harvard clinical study indicates that low dosages (300-600mg/day) are sufficient when treating unipolar depression. In fact, low dosages might actually be necessary. At 300mg/day, there are generally no side effects, and the risk of kidney or thyroid damage is negligible.

I am interested to know what other people have experienced with low-dosage lithium.


- Scott

 

Re: Anyone concerned about Dementia??

Posted by Lamdage22 on January 20, 2021, at 0:49:16

In reply to Re: Anyone concerned about Dementia??, posted by SLS on January 19, 2021, at 21:45:21

Good stuf. It helps with suicidality at 225.

> I am interested to know what other people have experienced with low-dosage lithium.
>
>
> - Scott

 

Re: Anyone concerned about Dementia??

Posted by creepy on January 20, 2021, at 15:15:43

In reply to Anyone concerned about Dementia??, posted by jay2112 on January 9, 2021, at 22:31:26

I am 50 also and I have had physical symptoms of depression in the last 10 years. cognitive and motor slowing, slow halting speech etc. and yes I really worry about dementia too.

symptoms of depression can become physical and mimic demetia. I had a doctor call this 'pseudo-dementia' awhile back.

What did resolve these symptoms for me (but not the emotional issues) was TMS.

I think the lack of activity and high carbohydrate intake thats common in depressives also contributes to the physical symptoms.


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