Psycho-Babble Medication Thread 1112712

Shown: posts 1 to 13 of 13. This is the beginning of the thread.

 

Alternatives to Caplyta

Posted by Sac on November 30, 2020, at 17:54:35

I have been on Caplyta for over two months, now insurance wont cover it. I was doing very well. Any suggestions for alternatives? I have TRD , currently taking 40 mg
Prozac and 450mgs lithium daily. Off for four days now and starting to spiral

 

Re: Alternatives to Caplyta

Posted by rjlockhart37 on November 30, 2020, at 20:53:43

In reply to Alternatives to Caplyta, posted by Sac on November 30, 2020, at 17:54:35

i researched a bit, caplyta from sources is both dopamine and serotonin it hits, there is another alternative called Nuplazid, but its under treatment for parkinson's psychosis. I don't think it would be a alternative, plus it was just released and may not be covered. Rexulti is atypical antipsychotic but it helps depression more, than schizophrenia. Invega, and saphris may be choices, but i havent researched those if they are equal alternatives

 

Re: Alternatives to Caplyta

Posted by rjlockhart37 on November 30, 2020, at 20:56:38

In reply to Re: Alternatives to Caplyta, posted by rjlockhart37 on November 30, 2020, at 20:53:43

zyprexs hits serotonin and dopamine, but the only problem = weight gain big time

 

Re: Alternatives to Caplyta

Posted by rjlockhart37 on November 30, 2020, at 21:08:29

In reply to Re: Alternatives to Caplyta, posted by rjlockhart37 on November 30, 2020, at 20:53:43

https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/209500s000lbl.pdf

look for mechanism of action and pharmacodynamics

 

Re: Alternatives to Caplyta

Posted by Christ_empowered on December 1, 2020, at 14:23:30

In reply to Alternatives to Caplyta, posted by Sac on November 30, 2020, at 17:54:35

hi. sorry about this. :-(

i would guess (?) a low to mid-potency 'atypical' tranquilizer might (?) do the trick. I know, really helpful. zyprexa has been studied in combination with prozac. seems to work well. a fixed combination, Symbyax, is available...I think its generic, now. could be wrong.

seroquel is the classic go-to. dosage titration takes a while.

even (very) low dose risperidone has been used with some success in some cases of depression. again, I know: not very reassuring. ugh. this is psychiatry, not...you know...'science,' so I"m just throwing out ideas for you.

seroquel, zyprexa, and risperidone are available in generics. not sure about seroquel xr.

a thought...have you ever tried lamictal? with lithium on board...wow, i don't know if its the best idea...but it is sometimes used in unipolar depression.

hope this helps.

 

Re: Alternatives to Caplyta

Posted by Sac on December 1, 2020, at 20:43:57

In reply to Re: Alternatives to Caplyta, posted by Christ_empowered on December 1, 2020, at 14:23:30

Thank you for the input and suggestions. Ive been on zyorexa, risperdal, seroquel , and lamictal in the past. I never had as robust an effect as far as lifting my depression than with Caplyta. I almost felt like I did before I ever had depression and anxiety. Its really an interesting medication as it helped both anxiety and depression plus helped with motivation and focus. I do agree that something along the lines of an atypical AP with mild tranquilizing effects would be ideal.

 

Re: Alternatives to Caplyta

Posted by Sac on December 2, 2020, at 21:12:56

In reply to Re: Alternatives to Caplyta, posted by Christ_empowered on December 1, 2020, at 14:23:30

Thank you for the input and suggestions. Ive been on zyorexa, risperdal, seroquel , and lamictal in the past. I never had as robust an effect as far as lifting my depression than with Caplyta. I almost felt like I did before I ever had depression and anxiety. Its really an interesting medication as it helped both anxiety and depression plus helped with motivation and focus. I do agree that something along the lines of an atypical AP with mild tranquilizing effects would be ideal.

 

Re: Alternatives to Caplyta

Posted by Christ_empowered on December 3, 2020, at 7:17:51

In reply to Re: Alternatives to Caplyta, posted by Sac on December 2, 2020, at 21:12:56

hi. sorry about this :-(

have you tried BuSpar? its cheap, generic...not all that amazing, but it can boost serotonin antidepressants, or so said a former shrink (then again...she wanted me on it...hmmmm...).

my final, random, just...kind of occurred to me suggestion...would be one of the old Triavil formulations, available in generic since...forever, really.

Triavil is Elavil and perphenazine, in fixed combinations. some have lower amounts of elavil and higher amounts of perphenazine (what was once called "Schizophrenic depression," and would now be considered probably psychotic depression, maybe Schizoaffective), and then some are the opposite-- higher elavil, lower perphenazine (agitated depression, maybe some sort of mixed states).

just...again, a random thought. not ideal, but...in the big studies comparing antipsychotics in Schizophrenia, perphenazine actually did almost as well as Zyprexa, just...lower costs, slightly more EPS. I was thinking that a low, low perphenazine dose might help smooth out anxiety, agitation, tension...while the elavil -might- help with mood and anxiety, overall. or not. not exactly the most pleasant medication in the whole wide world, but...yeah. yeah. a thought, nonetheless.

good luck. :-)

 

Re: Alternatives to Caplyta

Posted by Lamdage22 on December 3, 2020, at 7:46:59

In reply to Re: Alternatives to Caplyta, posted by Christ_empowered on December 3, 2020, at 7:17:51

To summarize: Just take a bunch of psychopharmaceuticals man. Its not that hard.

 

Re: Alternatives to Caplyta

Posted by Lamdage22 on December 3, 2020, at 8:02:02

In reply to Re: Alternatives to Caplyta, posted by Lamdage22 on December 3, 2020, at 7:46:59

My bad. Sarcasm. I shouldnt read this bosrd that much. Every once in a while there is something useful for me but often there is not.

 

Re: Alternatives to Caplyta

Posted by Lamdage22 on December 9, 2020, at 2:44:14

In reply to Re: Alternatives to Caplyta, posted by Lamdage22 on December 3, 2020, at 8:02:02

Sorry guys, this was not good. I'll try to contain myself in the future. This is the meds board, so meds are recommended. The doctor should really be the one who makes wise choices, not the patients. But yeah, this is not an ideal world. Meds are not always necessary.

 

Re: Alternatives to Caplyta

Posted by Christ_empowered on December 11, 2020, at 10:02:16

In reply to Re: Alternatives to Caplyta, posted by Lamdage22 on December 9, 2020, at 2:44:14

i was just trying to be helpful. its odd to me, that something so very new and still being marketed primarily for psychotic disorders, is being used in a non-psychotic mood disorder. but...

it is what it is, I suppose. mad in america did a big expose on this drug, in particular...their 'experts' say its no different from any other sedating, lower potency tranquilizer, but...then you have people who have actually taken it who say it is, so...???

 

Re: Alternatives to Caplyta

Posted by Skeletor on December 13, 2020, at 6:32:21

In reply to Alternatives to Caplyta, posted by Sac on November 30, 2020, at 17:54:35

> I have been on Caplyta for over two months, now insurance wont cover it. I was doing very well. Any suggestions for alternatives? I have TRD , currently taking 40 mg
> Prozac and 450mgs lithium daily. Off for four days now and starting to spiral
>
>

I would probably try Aripiprazole if I were in your shoes. It's quite interesting, due to its partial Dopamine and 5HT2C agonism...


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