Psycho-Babble Medication Thread 1112871

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Does Ingrezza (valbenazine) work? Any experiences?

Posted by SLS on December 10, 2020, at 12:49:59

My friend is ready to start taking Ingrezza (valbenazine) for the treatment of mild tardive dyskinisia that is affecting her tongue.

She asked me to post a question here. Does anyone have experience with Ingrezza?

Robert Post, MD told her that he has seen it work on some people. He didn't sound very excited about it, though.

There aren't very many people offering personal experiences with Ingrezza that I could find on Google. Those that I did find reported that Ingrezza produced drooling. When looking over the side effects, many of them seemed very similar to neuroleptic EPS. What's that all about?

Thanks.


- Scott

 

Re: Does Ingrezza (valbenazine) work? Any experiences? SLS

Posted by undopaminergic on December 11, 2020, at 9:04:35

In reply to Does Ingrezza (valbenazine) work? Any experiences?, posted by SLS on December 10, 2020, at 12:49:59

>
> There aren't very many people offering personal experiences with Ingrezza that I could find on Google. Those that I did find reported that Ingrezza produced drooling. When looking over the side effects, many of them seemed very similar to neuroleptic EPS. What's that all about?
>

Well, it seems intuitive that two classes of drugs which produce the same effect through different mechanisms of action would also share many adverse effects.

As you know, neuroleptics block dopamine receptors, and valbenazine depletes neuronal stores of dopamine.

Hence parkinsonian-like symptoms.

-undopaminergic

 

Re: Does Ingrezza (valbenazine) work? Any experiences?

Posted by Christ_empowered on December 11, 2020, at 10:00:30

In reply to Re: Does Ingrezza (valbenazine) work? Any experiences? SLS, posted by undopaminergic on December 11, 2020, at 9:04:35

it sounds an awful lot like reserpine and the old school rauwolfia alkaloids, just...extremely expensive.

 

Re: Does Ingrezza (valbenazine) work? Any experiences?

Posted by undopaminergic on December 11, 2020, at 10:16:40

In reply to Re: Does Ingrezza (valbenazine) work? Any experiences?, posted by Christ_empowered on December 11, 2020, at 10:00:30

> it sounds an awful lot like reserpine and the old school rauwolfia alkaloids, just...extremely expensive.
>

Right, that is my impression too.

Lobeline and tetrabenazine are others like it.

-undopaminergic

 

Re: Does Ingrezza (valbenazine) work? Any experiences?

Posted by SLS on December 14, 2020, at 11:58:47

In reply to Re: Does Ingrezza (valbenazine) work? Any experiences?, posted by undopaminergic on December 11, 2020, at 10:16:40

Thanks, guys. That was very helpful.


- Scott


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