Psycho-Babble Medication Thread 1112646

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Phentermine + MAOI? (definite no?)

Posted by PeterMartin on November 23, 2020, at 19:04:09

Has anyone ever taken Phentermine for weight loss while on an MAOI (specifically Marplan or Nardil)?

I only found one real thread on the subject from search, but no one who had tried or considered the combo chimed inL http://www.dr-bob.org/babble/20130730/msgs/1048080.html

I don't think I'll attempt it (I'm currently taking Marplan and could use losing 30lbs or so), but my GF is starting it so it's definitely tempting. She's lost a lot on phentermine in the past w/o much effort.

Thx for any insight.

 

Re: Phentermine + MAOI? (definite no?)

Posted by Christ_empowered on November 23, 2020, at 21:19:02

In reply to Phentermine + MAOI? (definite no?), posted by PeterMartin on November 23, 2020, at 19:04:09

id vote thumbs down. do you think the doctor who prescribes the marplan might be willing to try a stimulant to boost the mood elevating effects? im not really sure why, but it seems from my very limited, casual skimming of the old literature that amphetamines (even desoxyn) were often used with MAOIs "back then," but Ritalin not so much. given that the literature on any stimulant+MAOI combination is scant, I doubt there's much out there on the milder stimulants prescribed specificially for weight loss.

the amphetamines, of course, were commonly used as diet pills until the 70s or so, when the dea started cracking down on uppers. evekeo, i think, is the newer amphetamine out, now, that is actually a recycled, old formula (Biphetamine, perhaps?), and as such comes in with an old school indication: weight loss. I doubt the official indications of any given stimulant would be an issue, unless...I dunno, it becomes one, somehow. lol.

just...my advice is obviously -no- , with the added suggestion that you consider talking to your current treatment person/people about the possibility of (I would assume low dose) stimulant augmentation, for mood and weight. that way, if its a-OK, you can get proper monitoring, medication that's been used in combination with the marplan, etc.

hope this helps.

 

Re: Phentermine + MAOI? (definite no?)

Posted by sigismund on November 24, 2020, at 0:49:46

In reply to Re: Phentermine + MAOI? (definite no?), posted by Christ_empowered on November 23, 2020, at 21:19:02

I wouldn't. The pressor effects of phentermine are strong.

 

Re: Phentermine + MAOI? (definite no?)

Posted by undopaminergic on November 24, 2020, at 1:15:54

In reply to Re: Phentermine + MAOI? (definite no?), posted by sigismund on November 24, 2020, at 0:49:46

> I wouldn't. The pressor effects of phentermine are strong.

According to Wikipedia, it also releases some serotonin, a dangerous effect in combination with MAOIs. With caution (starting with very low doses) you could still try it.

-undopaminergic

 

Re: Phentermine + MAOI? (definite no?)

Posted by Petermartin on November 24, 2020, at 2:55:09

In reply to Re: Phentermine + MAOI? (definite no?), posted by undopaminergic on November 24, 2020, at 1:15:54

Thanks all - kinda what I figured but wanted to hear it.

Btw c_e I did take a normal dose (60mg) of ritalin w Nardil and then Marplan for almost a year. Obviously w/ my doctor approval - we just went slow and monitored bp.

I would never have tried/suggest adderall due to the potential for serotonin. It never really worked for me anyway (and didn't lower my weight). Phentermine was a tempting idea for the wt loss, but yeah, guess it does but serotonin so I can't go that route at the moment.


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