Psycho-Babble Medication Thread 1109411

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wellbutrin how's it working for you?

Posted by rjlockhart37 on April 4, 2020, at 21:12:19

its been 10 years since on wellbutrin, i do rerember it's activating propeties a very mild euphoria sometimess. I was on Aplenzin, its diffrent mechanis, than Wellbutrin XL. If ever went back it would be Wellbutrin XL. It released in the morning, then midday, then around 5-6pm i could feel a small mood lift, after i was tired. I rerember after school was over, i would be tired sittinb in the buisness, couselors office, and then strangely feeling a kick, or mild euphoria mood lift. I realized that's because of the XL release form. First started it, i was a bit more alert, and motivated to assginements, and improved mood some. Junior year of high schoool, i would run cross country in the mornings, was a bit more alert. After season was over, i would come to class and just have no motivation at all, just sit there and lay on the desk, feel falling asleep. Had to wait till adderall kicked in. But then for a while, i noticed wellbutrin would activate me, and we had papers to write, and started writing with more motivation.

It's a mild dopamine reptake inhibtor, mild stimulant. But its more on norephinpejhirne, because i had anxiety problems on it. I went up to 450 on XL form, yes it was a small amphetamine like stimulation but it faded, but i was focused and in motivated mood, but.....the anxiety it caused, i could not take naps during the day. Back in high school, no doctor would prescribe a benzo. I had to deal with bupropion edginess all day. It had pros and cons, 300mg was more anti-depressant effect, 450 was more focus enhancement and cognitive improvement. I eventually stopped it. I went on Aplenzin, no, the XL form i think is the best. It releases 3 times a day, so at 9am i could feel it, then around 1pm would feel another bupropion lift, then at 5-6pm being tired from the day. I would feel a kick and could finish tasks.

____________________________________

Anyways, that's just my experience with it. So, how is working, is helping depression. Just leave reply and see how doing on it

 

Re: wellbutrin how's it working for you?

Posted by undopaminergic on April 5, 2020, at 12:09:26

In reply to wellbutrin how's it working for you?, posted by rjlockhart37 on April 4, 2020, at 21:12:19

I noticed no effects of bupropion (Voxra) with doses up to 900 mg.

-undopaminergic

 

Re: wellbutrin how's it working for you?

Posted by rjlockhart37 on April 5, 2020, at 15:31:59

In reply to Re: wellbutrin how's it working for you?, posted by undopaminergic on April 5, 2020, at 12:09:26

are you serious? i took 650 one time, the XL form, and i was at denny's eating lunch with my brother, and all of sudden, just, i've never had a seizure, but this definitely felt like one, or like maybe one was coming on. And i had to deal with this, feeling all day, it was like a feeling of seizure coming on.

Wow 900 mg of bupropion, what were effects of it, did it give an enhanced feeling, or make you irritable?

I one time on Aplenzin took 800mg of it, but i was drunk, i had a lot of whiskey and ..guess alcohol works on GABA and can prevent seizures, but that's i don't know that as a fact, i went to a movie drunk and took 800mg of bupropion and noticed some difference but alcohol was more in effect.

What was it like? did you feel irritable, or more focused?

 

Re: wellbutrin how's it working for you?

Posted by rjlockhart37 on April 5, 2020, at 20:26:29

In reply to Re: wellbutrin how's it working for you?, posted by rjlockhart37 on April 5, 2020, at 15:31:59

i don't know....maybe i just start wellbutrin again, and get back on 450, then do a little test and see if 650 still gives seizure feeling. When they first released bupropion, it was not called bupropion, it was called Amfebutamone, in the US was released in 1985, then in 1988 or 1989 they withdraw it from the market short time because of seizures, the dose they were giving people was too much, yes it was like around 600-900mg, it causes seizure threshold. Lowered the max dose to 450, i think, maybe 600, not sure.

 

Re: wellbutrin how's it working for you?

Posted by undopaminergic on April 6, 2020, at 3:18:00

In reply to Re: wellbutrin how's it working for you?, posted by rjlockhart37 on April 5, 2020, at 15:31:59

> are you serious? i took 650 one time, the XL form, and i was at denny's eating lunch with my brother, and all of sudden, just, i've never had a seizure, but this definitely felt like one, or like maybe one was coming on. And i had to deal with this, feeling all day, it was like a feeling of seizure coming on.
>
> Wow 900 mg of bupropion, what were effects of it, did it give an enhanced feeling, or make you irritable?
>
> I one time on Aplenzin took 800mg of it, but i was drunk, i had a lot of whiskey and ..guess alcohol works on GABA and can prevent seizures, but that's i don't know that as a fact, i went to a movie drunk and took 800mg of bupropion and noticed some difference but alcohol was more in effect.
>
> What was it like? did you feel irritable, or more focused?

I'm serious, but I took the 900 mg dose only once.

No effect whatsoever. At least nothing I noticed. I was hoping for at least a little bit of a stimulant effect. Because this was a very high dose, and it still did not work, I decided to give up on bupropion.

I've never had a seizure. I seem to be very resistant to that.

-undopaminergic

 

Re: wellbutrin how's it working for you?

Posted by rjlockhart37 on April 7, 2020, at 15:38:38

In reply to Re: wellbutrin how's it working for you?, posted by undopaminergic on April 6, 2020, at 3:18:00

i've read studies, and its like i can't go back and read the source, because i read it a long time ago. But i read that there was 400mg buprion in one dose, produced mild stimulantion to amphetamine, and caused sterotype behavior. When i was on it, it was activating and keeps you buproponized but not like stimulants. At 450 XL, the xl form releases 3 times in pill, first when you take it, say like 9am, there would be 150mg of bupropn released, then at midnoon same thing, then around 5-6pm last release of it, so its like your getting 150 mg every 4-5 hours. It has a short half life that's why they use XL forms so you don't have redose.

When i took 650, it was 220mg being released every 4 hours. And it was not pleasant. In US it was released in '85 and they used doses up to 900, they withdrew it because of seizures, then put it back on market with a lowered maximum dose.


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