Psycho-Babble Medication Thread 1107284

Shown: posts 1 to 7 of 7. This is the beginning of the thread.

 

Original MAOI vs TCA studies

Posted by linkadge on December 17, 2019, at 17:27:31

I have been reading some articles on original comparisons between imipramine and phenelzine. Many (if not most) studies indicated the phenelzine was more effective than imipramine.

Interesting.

Linkadge

 

Re: Original MAOI vs TCA studies linkadge

Posted by undopaminergic on December 18, 2019, at 6:58:05

In reply to Original MAOI vs TCA studies, posted by linkadge on December 17, 2019, at 17:27:31

> I have been reading some articles on original comparisons between imipramine and phenelzine. Many (if not most) studies indicated the phenelzine was more effective than imipramine.
>
> Interesting.
>
> Linkadge

Right. However, here's an exception:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1597363/pdf/brmedj00101-0007.pdf

I discovered this article while I was researching trimipramine, which I'm currently taking.

-undopaminergic

 

Re: Original MAOI vs TCA studies

Posted by sigismund on December 18, 2019, at 15:08:07

In reply to Re: Original MAOI vs TCA studies linkadge, posted by undopaminergic on December 18, 2019, at 6:58:05

I really liked low dose trimpiramine.

 

Re: Original MAOI vs TCA studies undopaminergic

Posted by linkadge on December 18, 2019, at 16:22:44

In reply to Re: Original MAOI vs TCA studies linkadge, posted by undopaminergic on December 18, 2019, at 6:58:05

Interesting. Of note, they said mild-moderate (not sure if severity is an issue). Also, supposedly there are some differences in response between melancholic and atypical subtypes.

I've been adding some MAOI herbs to venlafaxine and often notice a dramatic improvement.


Linkadge

 

Re: Original MAOI vs TCA studies sigismund

Posted by linkadge on December 18, 2019, at 16:24:38

In reply to Re: Original MAOI vs TCA studies, posted by sigismund on December 18, 2019, at 15:08:07

I would second that. I found trimipramine better than mirtazapine. On paper, they should be similar. Trimipramine had more of an anti-anhedonic effect. Not sure why.

Linkadge

 

Re: Original MAOI vs TCA studies linkadge

Posted by undopaminergic on December 19, 2019, at 7:18:55

In reply to Re: Original MAOI vs TCA studies sigismund, posted by linkadge on December 18, 2019, at 16:24:38

> I would second that. I found trimipramine better than mirtazapine. On paper, they should be similar. Trimipramine had more of an anti-anhedonic effect. Not sure why.
>
> Linkadge

I wouldn't go so far as to call it anti-anhedonic, but I've noticed some anti-apathetic effects myself, especially at the start, with a dose of only 25 mg. I found it gave me more of a choice over whether to be active or rest.

I notice less with 50 mg, which I've been on for months now.

I think these effects may be related to the fact that it is a histamine H2-receptor antagonist. See the studies of famotidine in schizophrenia.

-undopaminergic

 

Re: Original MAOI vs TCA studies

Posted by linkadge on December 20, 2019, at 19:54:20

In reply to Re: Original MAOI vs TCA studies linkadge, posted by undopaminergic on December 19, 2019, at 7:18:55

All I remember from trimipramine was sleeping till 3pm and then waking up and feeling great - like I had entered a new world. Things looked and felt different - a newness.

Linkadge


This is the end of the thread.


Show another thread

URL of post in thread:


Psycho-Babble Medication | Extras | FAQ


[dr. bob] Dr. Bob is Robert Hsiung, MD, bob@dr-bob.org

Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.