Psycho-Babble Medication Thread 1107024

Shown: posts 1 to 12 of 12. This is the beginning of the thread.

 

Question for Bipolars

Posted by linkadge on December 5, 2019, at 19:29:14

Do you experience sleep issues?

If so, do you suffer from more hypersomnia (oversleeping) or insomnia?

I just read an article that suggested (on a genetic level) that BPI was associated with more oversleeping, whereas BPII was associated with more insomnia.

What do you experience? (or neither).

Linkadge

 

Re: Question for Bipolars

Posted by Lamdage22 on December 6, 2019, at 6:34:01

In reply to Question for Bipolars, posted by linkadge on December 5, 2019, at 19:29:14

Not sure if I am bipolar but I overlseep

 

Re: Question for Bipolars » linkadge

Posted by beckett2 on December 6, 2019, at 10:19:44

In reply to Question for Bipolars, posted by linkadge on December 5, 2019, at 19:29:14

I've experienced all of the above; however, insomnia has been the greater bane. Hypersomnia on it's own, I can deal with.

BPll, formerly cyclothymia.

What do you experience?

 

Re: Question for Bipolars

Posted by linkadge on December 6, 2019, at 16:55:45

In reply to Re: Question for Bipolars » linkadge, posted by beckett2 on December 6, 2019, at 10:19:44

I experience much more insomnia than hypersomnia.

Linkadge

 

Re: Question for Bipolars

Posted by phidippus on December 6, 2019, at 21:14:53

In reply to Question for Bipolars, posted by linkadge on December 5, 2019, at 19:29:14

I suffer mostly from early awakenings where I can't get back to sleep. I also get insomnia from time to time. I don't think I oversleep much. I'm bipolar I.

There's a wonderful drug for sleep called Xyrem, which is basically GHB.

 

Re: Question for Bipolars

Posted by linkadge on December 7, 2019, at 7:50:30

In reply to Re: Question for Bipolars, posted by phidippus on December 6, 2019, at 21:14:53

Are you prescribed xyrem?

Linkadge

 

Re: Question for Bipolars » linkadge

Posted by phidippus on December 7, 2019, at 19:07:19

In reply to Re: Question for Bipolars, posted by linkadge on December 7, 2019, at 7:50:30

I was prescribed for a short time. The drawback is you take a dose, sleep for four hours then dose again and sleep another however many hours.

 

Re: Question for Bipolars

Posted by sigismund on December 7, 2019, at 19:52:41

In reply to Re: Question for Bipolars » linkadge, posted by phidippus on December 7, 2019, at 19:07:19

> The drawback is you take a dose, sleep for four hours then dose again and sleep another however many hours.

Just like the zolpidem I could buy os. Loved it.

 

Re: Question for Bipolars » linkadge

Posted by undopaminergic on December 8, 2019, at 10:16:22

In reply to Question for Bipolars, posted by linkadge on December 5, 2019, at 19:29:14

> Do you experience sleep issues?
>

Yes.

> If so, do you suffer from more hypersomnia (oversleeping) or insomnia?
>

Kind of both.

For most of my life, in my natural (drug-free) condition, it has always taken too long to fall asleep. I have used hypnotics for periods.

Also for most of my life (save a [hypo]manic episode or when taking reboxetine (Edronax)), I have always been too tired in the morning. I am a regular stimulant-fiend when left to my own devices. An important reason for this usage, is to get started with my day, although I also sleep much less thanks to these drugs, so there will be fewer "mornings" (in the sense of "awakenings").

More recently in my life, a persistent problem is the poor quality of my sleep. Essentially, it feels useless. If I did not have apathy, I would sleep much less, as the only benefit of sleep is a measure of relative relief from this symptom I get when I finally get out of the initial sleepiness in the mornings. If I did not take antihistamines in the evenings, I would at least stay up and active longer. Indeed, sometimes I am able to push through the fatigue (and apathy) from the drugs and so stay up longer.

> I just read an article that suggested (on a genetic level) that BPI was associated with more oversleeping, whereas BPII was associated with more insomnia.
>

Interesting. It would be interesting to compare with other populations, such as "normal" people, Parkinsonians, ADDers, schizophrenics, etc..

-undopaminergic

 

Re: Question for Bipolars » phidippus

Posted by undopaminergic on December 8, 2019, at 10:21:12

In reply to Re: Question for Bipolars » linkadge, posted by phidippus on December 7, 2019, at 19:07:19

> I was prescribed for a short time. The drawback is you take a dose, sleep for four hours then dose again and sleep another however many hours.
>

So where is the drawback? Do you get too little or too much sleep?

I have read that this drug (GHB) suppresses dopamine release acutely, and when it wears off there is a dopamine rebound that basically makes you feel awake and motivated (ie. lack of apathy).

-undopaminergic

 

Re: Question for Bipolars » undopaminergic

Posted by phidippus on December 10, 2019, at 16:46:21

In reply to Re: Question for Bipolars » phidippus, posted by undopaminergic on December 8, 2019, at 10:21:12

The drawback is having to wake up in the middle of the night to redose. But you do get the right amount of sleep. As far as dopamine release goes,
the present report suggests that GHB does inhibit rather than stimulate presynaptic DA release in consonance with its behavioral and pharmacological activity. Recent in vivo studies indicating that GHB stimulates DA release were done under anaesthesia or in the presence of a high concentration of calcium. Both conditions have been found to spuriously enhance striatal DA release in vivo, which may account for the failure of some studies to observe an inhibitory effect of GHB on DA release in vivo.

 

Re: Question for Bipolars » phidippus

Posted by undopaminergic on December 11, 2019, at 8:49:51

In reply to Re: Question for Bipolars » undopaminergic, posted by phidippus on December 10, 2019, at 16:46:21

> The drawback is having to wake up in the middle of the night to redose.
>

If it were me, I would not redose, but rather get up and get my new day started. I like to see it as if waking up means you're rested enough.

-undopaminergic


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