Psycho-Babble Medication Thread 1106785

Shown: posts 1 to 25 of 32. This is the beginning of the thread.

 

Palmitoylethanolamide

Posted by Lamdage22 on November 14, 2019, at 22:18:25

I am considering this. Did anyone try?

 

Re: Palmitoylethanolamide

Posted by sigismund on November 14, 2019, at 22:24:43

In reply to Palmitoylethanolamide, posted by Lamdage22 on November 14, 2019, at 22:18:25

No, but I am interested.

 

Re: Palmitoylethanolamide

Posted by sigismund on November 14, 2019, at 22:49:41

In reply to Re: Palmitoylethanolamide, posted by sigismund on November 14, 2019, at 22:24:43

https://www.ncbi.nlm.nih.gov/pubmed/?term=Palmitoylethanolamide

There's quite a few there. Works on the cannabinoid system?

I should get some. Many older people have chronic pain.

 

Re: Palmitoylethanolamide

Posted by Lamdage22 on November 14, 2019, at 22:51:56

In reply to Re: Palmitoylethanolamide, posted by sigismund on November 14, 2019, at 22:49:41

Yes, it does. I am signed up for the traditional Chinese medicine guy but I think I may want to try Palmitoylethanolamide first.

 

Re: Palmitoylethanolamide

Posted by sigismund on November 14, 2019, at 22:52:58

In reply to Re: Palmitoylethanolamide, posted by sigismund on November 14, 2019, at 22:49:41

Abstract
Palmitoylethanolamide (PEA) is a nutraceutical endocannabinoid that was retrospectively discovered in egg yolks. Feeding poor children with known streptococcal infections prevented rheumatic fever. Subsequently, it was found to alter the course of influenza. Unfortunately, there is little known about its pharmacokinetics. Palmitoylethanolamide targets nonclassical cannabinoid receptors rather than CB1 and CB2 receptors. Palmitoylethanolamide will only indirectly activate classical cannabinoid receptors by an entourage effect. There are a significant number of prospective and randomized trials demonstrating the pain-relieving effects of PEA. There is lesser evidence of benefit in patients with nonpain symptoms related to depression, Parkinson disease, strokes, and autism. There are no reported drug-drug interactions and very few reported adverse effects from PEA. Further research is needed to define the palliative benefits to PEA.

 

Re: Palmitoylethanolamide

Posted by Lamdage22 on November 14, 2019, at 22:56:42

In reply to Re: Palmitoylethanolamide, posted by sigismund on November 14, 2019, at 22:52:58

If it helps pain there is a chance it helps mental pain as well. https://www.ncbi.nlm.nih.gov/pubmed/29486338

 

Re: Palmitoylethanolamide

Posted by sigismund on November 15, 2019, at 1:37:36

In reply to Re: Palmitoylethanolamide, posted by Lamdage22 on November 14, 2019, at 22:56:42

My experience of pain has been that anything that makes me feel better helps me cope with it, so maybe it works the other way round, if that makes sense.

 

Re: Palmitoylethanolamide

Posted by sigismund on November 15, 2019, at 1:52:47

In reply to Re: Palmitoylethanolamide, posted by sigismund on November 15, 2019, at 1:37:36

Nothing works for nerve pain, so this experience interested me.......

As for it working or not... I'm no Doctor but I am aware of what I take for pain control and what works for me. My original surgery was a lamenectomy to stop sciatica. I had for many years used anti-inflammatory drugs. They never quite stopped the pain. Spinal injections by a self styled pain control GP had some effect but it never lasted very long. I've formed the opinion now that there are two types of back pain. One is as a result of inflammation usually caused by narrowing of discs (slipped disk) and the other is just plain old back pain that can be treated with pain killers.

Anyone intending to 'try' PEA needs to be aware that it has the most effect where inflammatory pain is present. It is not in my opinion a 'pain killer' and it costs some serious money to keep buying it.

I was on 180 mg of Morphine daily for nearly 5 years. It didn't really stop the pain from several back operations and an infection of Golden Staph. The last surgery was monstrous. 2 steel rods, 12 bolts and several plates to hold fusion of L2, L3 L4, L5 and S1 and no... I can't do up my shoe laces now! I hope this answers some questions and opens the door to how to get it in Australia.

 

Re: Palmitoylethanolamide

Posted by Lamdage22 on November 15, 2019, at 6:39:03

In reply to Re: Palmitoylethanolamide, posted by sigismund on November 15, 2019, at 1:52:47

Well, I don't have any physical pain... I would be in it for the psychological effects. Less studied, but it may still work.

 

Re: Palmitoylethanolamide

Posted by Lamdage22 on November 15, 2019, at 9:33:33

In reply to Re: Palmitoylethanolamide, posted by Lamdage22 on November 15, 2019, at 6:39:03

I am looking at several things right now. I am using monk fruit as of yesterday, I will start taking 3 divided doses of Trazodone during the day tomorrow, I will see a Chinese herbalist on Monday and I ordered this Palmitoylethanolamide stuff.

If I do everything at once I won't know which helps. Any tipps?

Maybe the latter two not at once?

Will post here if there is news with Palmitoylethanolamide


 

Re: Palmitoylethanolamide

Posted by sigismund on November 15, 2019, at 17:24:48

In reply to Re: Palmitoylethanolamide, posted by Lamdage22 on November 15, 2019, at 9:33:33

https://www.michaelnegraeff.com/blog/2015/7/11/three-things-i-learned-during-a-personal-trial-of-pea

Something to do with mast cells? And therefore allergies?

 

Re: Palmitoylethanolamide

Posted by Lamdage22 on November 16, 2019, at 10:43:59

In reply to Re: Palmitoylethanolamide, posted by sigismund on November 15, 2019, at 17:24:48

It seems to be good for neurons and inflammation in general.

 

Re: Palmitoylethanolamide

Posted by Lamdage22 on November 27, 2019, at 12:47:00

In reply to Re: Palmitoylethanolamide, posted by Lamdage22 on November 16, 2019, at 10:43:59

I am about a week into 1200mg Palmitoylethanolamide. I feel better but there could be other reasons for this. I bought 60 pills and when they are gone I will see if feeling better abates if i don't take it or not. That's the only way to tell because I have changed several things at once.

 

Re: Palmitoylethanolamide » Lamdage22

Posted by sigismund on December 3, 2019, at 16:08:21

In reply to Re: Palmitoylethanolamide, posted by Lamdage22 on November 27, 2019, at 12:47:00

I suppose that is the right dose.

https://www.ncbi.nlm.nih.gov/pubmed/30534062

 

Re: Palmitoylethanolamide

Posted by Lamdage22 on December 14, 2019, at 3:40:18

In reply to Re: Palmitoylethanolamide » Lamdage22, posted by sigismund on December 3, 2019, at 16:08:21

Ok, the effect is very mild. It might enable me to study a little longer but if cost is an issue maybe there are better options. I have been taking it for 25 days.

 

Re: Palmitoylethanolamide

Posted by sigismund on December 14, 2019, at 15:04:15

In reply to Re: Palmitoylethanolamide, posted by Lamdage22 on December 14, 2019, at 3:40:18

I can't say I notice anything. Maybe it has been 14 days.

 

Re: Palmitoylethanolamide

Posted by Lamdage22 on December 14, 2019, at 15:24:52

In reply to Re: Palmitoylethanolamide, posted by sigismund on December 14, 2019, at 15:04:15

Do you have pills for 30 days?

 

Re: Palmitoylethanolamide

Posted by sigismund on December 14, 2019, at 22:36:39

In reply to Re: Palmitoylethanolamide, posted by Lamdage22 on December 14, 2019, at 15:24:52

For a couple of months. There are 2 of us with pain or prospects for it, so I thought I'd give it a go.

 

Re: Palmitoylethanolamide

Posted by Lamdage22 on December 15, 2019, at 8:24:38

In reply to Re: Palmitoylethanolamide, posted by sigismund on December 14, 2019, at 22:36:39

I think it can take up to 30 days to get a response. However, i dont expect much. But who knows? I certainly dont have side effects!

 

Re: Palmitoylethanolamide

Posted by sigismund on December 29, 2019, at 0:08:17

In reply to Re: Palmitoylethanolamide, posted by Lamdage22 on December 15, 2019, at 8:24:38

https://www.longecity.org/forum/topic/91678-pea-palmitoylethanolamide-natural-safe-affordable-and-effective/

 

Re: Palmitoylethanolamide

Posted by Lamdage22 on January 3, 2020, at 3:50:40

In reply to Re: Palmitoylethanolamide, posted by sigismund on December 29, 2019, at 0:08:17

Hi sigismund,

I am dieting successfully ever since I have started with the PEA! Maybe not a coincidence?

 

Palmitoylethanolamide: I have lost serious weight!

Posted by Lamdage22 on January 3, 2020, at 7:09:27

In reply to Re: Palmitoylethanolamide, posted by sigismund on December 29, 2019, at 0:08:17

So I have begun a diet and have lost 11 lbs. The start was concurrent with starting Palmitoylethanolamide. I am looking to lose another 22!
Is it possible that it helps me with this? Also I am a little more clear-headed and have a little more endurance studying!

Whats the science behind this?

 

Re: Palmitoylethanolamide: I have lost serious weight!

Posted by Lamdage22 on January 3, 2020, at 7:15:44

In reply to Palmitoylethanolamide: I have lost serious weight!, posted by Lamdage22 on January 3, 2020, at 7:09:27

Also concurrent with monk fruit which is a sweetener. Its pretty cool with no side effects!

 

Re: Palmitoylethanolamide: I have lost serious weight!

Posted by Lamdage22 on January 4, 2020, at 5:01:02

In reply to Re: Palmitoylethanolamide: I have lost serious weight!, posted by Lamdage22 on January 3, 2020, at 7:15:44

I will have my mother try it who also has weight gain issues. Going to keep you posted.

 

Re: Palmitoylethanolamide

Posted by undopaminergic on January 20, 2020, at 7:03:00

In reply to Re: Palmitoylethanolamide, posted by sigismund on November 15, 2019, at 1:52:47

>
> I was on 180 mg of Morphine daily for nearly 5 years.

Wow, that's a lot! Was it due to tolerance that you had to go so high?

-undopaminergic


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