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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by AgentScully on December 7, 2010, at 4:01:50
I am discontinuing Adderall next week and I am terrified of the depression that will inevitably follow. I need to know what I can take to start repairing my dopamine receptors. I know that l-tyrosine works as a natural alternative, but what about prescription options? I am ordering some amineptine, which may take the edge off, but I don't know what to expect. I've heard curcumin eliminates withdrawal, so I ordered some. What meds can I take to soften the blow?
Posted by sigismund on December 8, 2010, at 5:51:57
In reply to Preparing for a dopamine crash, posted by AgentScully on December 7, 2010, at 4:01:50
> I've heard curcumin eliminates withdrawal, so I ordered some.
That's interesting.
It is definitely psychoactive, IME.
Posted by Conundrum on December 13, 2010, at 16:37:00
In reply to Re: Preparing for a dopamine crash » AgentScully, posted by sigismund on December 8, 2010, at 5:51:57
> > I've heard curcumin eliminates withdrawal, so I ordered some.
>
> That's interesting.
>
> It is definitely psychoactive, IME.Actually I think wellbutrin might be a better bet than aminetpine, I've read on addforums that it helped a lot of people coming off stimulants. Also amineptine is very short acting so it could leave you depleted after it wheres off, it has a short half life. Also adderall increases norepinephrine more than dopamine, so wellbutrin would help keep norepinephrine stores elevated for awhile as well. Also amineptine is really expensive as you know.
What happens with drugs that increase neurotransmitters is that receptors decrease in response to increased ligands. They start go back into the cell to prevent overstimulation. Over time the receptors will come back once the drug has been stopped and neurotransmitters decrease. It is, unfortunately unavoidable, but it is what the body must do to achieve balance.
Posted by Cydnie on February 22, 2011, at 10:07:57
In reply to Re: Preparing for a dopamine crash, posted by Conundrum on December 13, 2010, at 16:37:00
I don't know yet but am talking to a doc this week about natural supplements, and will ask about that since I want to do the same. I have read that things like rhodeola rosea is good, like you wrote l-tyrosine, I think magnesium, but I will write back and tell you if I find anything helpful. Good luck!
Posted by Chairman_MAO on October 6, 2011, at 14:19:19
In reply to Preparing for a dopamine crash, posted by AgentScully on December 7, 2010, at 4:01:50
That depends on what you can get your hands on. Off the top of my head, selegiline comes to mind.
This is the end of the thread.
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