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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by saturn on May 11, 2006, at 19:55:59
Posted by Larry Hoover on May 12, 2006, at 8:47:17
In reply to Is sucralose or it's metabolites (if any)absorbed?, posted by saturn on May 11, 2006, at 19:55:59
I was going to say:
"No. There are no metabolites, essentially. That's why they call it a non-caloric sweetener. It doesn't break down, so it does not produce energy." That's what I was going to say. Then I looked at the literature.Sucralose is 1,6-dichloro-1,6-dideoxy-beta-D-fructo-furanosyl 4-chloro-4-deoxy-alpha-D-galactopyranoside. The Wiki site contains the following quotation, from an Australian government safety analysis: "When administered orally, between 11% and 27% of sucralose is absorbed from the gastrointestinal tract in male humans. The remaining sucralose is excreted in feces. Following gastrointestinal absorption, between 20% and 30% of the sucralose is broken down into two metabolites. The remaining sucralose is excreted in urine."
One of those metabolites, 1,6-dichlorofructose, has never been tested for human safety.
When I look at the published literature, some unabashedly from the in-house laboratories of the manufacturer, and I find stuff like: "There were statistically significant increases in the incidence of several non-neoplastic findings, but these were not considered to be related to sucralose administration." and "adrenal cortical haemorrhagic degeneration....were of no toxicological significance...", I am apalled. They weren't testing a friggin' pesticide here, this is a food ingredient!
Your question has revealed to me just how much propaganda is out there. I almost gave you the propaganda answer.
I would not eat any sucralose if I knew it was in the food. Period.
Lar
Posted by saturn on May 13, 2006, at 18:56:18
In reply to Re: Is sucralose or it's metabolites (if any)absorbed? » saturn, posted by Larry Hoover on May 12, 2006, at 8:47:17
> Your question has revealed to me just how much propaganda is out there. I almost gave you the propaganda answer.
Yup, you really have to read between the lines.
Posted by joslynn on June 6, 2006, at 12:40:58
In reply to Re: Is sucralose or it's metabolites (if any)absorbed? » Larry Hoover, posted by saturn on May 13, 2006, at 18:56:18
I used to eat sucralose, until I read in the New Yorker that it was made from what was initially being tested as a pesticide! Someone told the researcher to test it and he thought the person said "taste it," so he did, and realized it was sweet.
I know this sounds like an urban legend, but it was in the New Yorker.
(I may have the pesticide part wrong...but I don't think so. I don't have the magazine with me.)
Posted by honeybee on June 9, 2006, at 16:39:45
In reply to Re: Is sucralose or it's metabolites (if any)absor, posted by joslynn on June 6, 2006, at 12:40:58
Isn't aspartame chemically very similar to cyanide (I write, as I blithely drink my diet coke)?
This is the end of the thread.
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