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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by Dr. Bob on February 13, 2004, at 9:01:10
In reply to migraine, posted by shortelise on February 13, 2004, at 1:36:31
> Just curious if many others here suffer from diagnosed migraine, ones that are treted with triptans, preventatives, etc. I have had them for the past 10 years or so, seen the neuros, specialists, etc. But do wonder how many others find migraine and depression are, as they say, comorbid.
>
> Thanks
> ShortE
Posted by Wildflower on February 13, 2004, at 10:00:03
In reply to migraine « shortelise, posted by Dr. Bob on February 13, 2004, at 9:01:10
I think they might be since both can be aggravated by stress. I've had migraines for quite some time although I have never gone as far as going to a neurologist.
> > Just curious if many others here suffer from diagnosed migraine, ones that are treted with triptans, preventatives, etc. I have had them for the past 10 years or so, seen the neuros, specialists, etc. But do wonder how many others find migraine and depression are, as they say, comorbid.
> >
> > Thanks
> > ShortE
>
Posted by Dinah on February 14, 2004, at 9:27:07
In reply to migraine « shortelise, posted by Dr. Bob on February 13, 2004, at 9:01:10
It wouldn't be surprising, since the latest theory is that migraines are caused by a cascade of neurotransmitters. I can't remember the sequence right now, but my neurologist had a neat little diagram.
Posted by shortelise on February 15, 2004, at 2:42:10
In reply to Re: migraine, posted by Dinah on February 14, 2004, at 9:27:07
I thought I knew everything there was to know about migraine - but I don't know what you're talking about. Any chance for more info on this?
Thanks
ShortE
Posted by Dinah on February 15, 2004, at 12:24:38
In reply to Dinah, posted by shortelise on February 15, 2004, at 2:42:10
I looked in all the most sensible places for my handout - the bottom of the pile of clean clothes, on top of my bureau, and can't find them. But here's an excerpt from:
http://nsweb.nursingspectrum.com/ce/ce133.htm
"Although the exact mechanisms remain under investigation most experts agree that the pain of migraine involves the serotonergic-adrenergic pain-modulating system, the central pain pathway that is modulated by serotonin and norepinephrine. Studies using positron emission tomography (PET) found that areas containing serotonergic cells, which light up during the test, are hyperactive during migraine. Cerebral blood flow in the brain stem structures also increases.
Although other neurotransmitters are involved, serotonin is one of the most significant in the migraine process — it is the one that is most successfully manipulated to control migraine pain. Ninety percent of serotonin is found in cells of the small intestine and much of the rest is found in the platelets and central nervous system. The remaining small but vital amount is located in cells in the brainstem that distribute their axons throughout the brain.
Serotonin is involved in sleep, mood change, cerebral arterial vascular activity, and thought and sensory perception. It also has a role in regulating the release of substance P, which increases capillary permeability so an exudate of fluid from the blood vessels leaks onto surrounding tissue. This, in turn, stimulates an inflammatory cascade that releases bradykinins and prostaglandins in the area. The presence of these substances increases the sensitivity of pain-conducting fibers and may cause spontaneous firing of nerves responsible for head pain."
Posted by Jai Narayan on February 19, 2004, at 18:35:32
In reply to migraine « shortelise, posted by Dr. Bob on February 13, 2004, at 9:01:10
I use Natures Plus Niacin every night for the flush and it has helped me to circumvent my headache as well. I have used niacin 200mg and not had a migraine for 17 years.
I had them bad.... they would last for a week at a time.
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