Psycho-Babble Alternative Thread 1024026

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Melatonin + MAOIs in Elderly w/Sundown Syndrome

Posted by theresa125 on August 23, 2012, at 13:03:18

My mother is 100 and has been experiencing what we believe is SS. She isn't sleeping well, is hallucinating, and has fearful thoughts and confusion, which usually begin around early evening. She is at an assisted living facility and they take good care of her and the other 7 ladies; mom's the oldest, but physically (and usually mentally), is in the best shape of them all.

I bought her melatonin lozenges (4 mg) to help her sleep at night, but I was wondering if it might interfere (or the other way around) with any MAOI she may be taking.

Does anyone know, or have another suggestion/solution on what she could take and how to help decrease the Sundowner's symptoms?

 

Re: Melatonin + MAOIs in Elderly w/Sundown Syndrome

Posted by Hugh on August 27, 2012, at 13:40:26

In reply to Melatonin + MAOIs in Elderly w/Sundown Syndrome, posted by theresa125 on August 23, 2012, at 13:03:18

Low dose naltrexone (LDN) might help. As far as I know, it doesn't interact with MAOIs. It increases opioid levels in the body, so it can have a calming effect. And some people claim that it slows or even halts the progression of Alzheimer's. Most people take it at bedtime, and it can interfere with sleep, especially in the first few weeks. There's a debate in the LDN community. Most think it's more effective when taken at bedtime. Others say it makes no difference what time of day it's taken.


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