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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 18 of 18. This is the beginning of the thread.
Posted by TylerJ on February 15, 2006, at 7:00:25
Hey does anyone know if it is safe to take SAMe with Parnate. From what I've read SAMe seems to be a wonderful supplement. I appreciate any info I can get. Thank you.
TylerJ
Posted by willyee on February 15, 2006, at 7:01:56
In reply to Parnate and sa--SAMe combination, posted by TylerJ on February 12, 2006, at 2:08:16
> Hey does anyone know if it is safe to take SAMe with Parnate. From what I've read SAMe seems to be a wonderful supplement. I appreciate any info I can get. Thank you.
>
> TylerJ
Bro i am not postive,but if my mind serves me youre just starting parnate correct? No offense but what are you thinking guy,,,,,no u dont want to use samE with parnate,i really dont advise this at all.
Explain how u are feeling on parnate,the level of benifit,what is missing,what do you "WANT" from it.......put as much info and let me or someone who knows parnate read it,but at a third day stage i would NOT touch samEYour still a newborn on it,you havent even yet ensured what diet restrictions u personaly might come across,
If youd like any help post ur dose ur on,how long i think u said 3 days,post again as much as u can think,and ill recomend simply what i would do.
As for samE blah,its snake oil,yeSS it crosses the brain,and has been used in Eurpope for years,i know all about it,but to me,.........This is a nutritnet that is crimanly OVERPRICED,and INSANLY overated.
At its best it will have a stimulant effect,close to caffiene,this is when it works,and you will spend ur money wad getting there.
Now i never speak for everyone i have seen people post they well on it,BUT i also seen many many posts where people come back saying it either dont work,OR caused them to feel maniac,hyper insomnia etc,and it is contradicted in maniac people.
Getting away from parnate,if i had to use something in this area,id look into Gotu Kola,DMG,TMG,NADH, or even DLPA.samE makes me cringe jus thinking of the cost and money i lost on it years ago.
Be safe!
Posted by TylerJ on February 15, 2006, at 7:01:56
In reply to Re: Parnate and sa--SAMe combination, posted by willyee on February 12, 2006, at 4:06:47
That's want I needed to hear-because you are my Parnate "advisor" I trust your judement Willyee and appreciate your advice, I can tell you are a very sincere and concerned friend. I may be a pain in the a** for you for a while-as I'm learning and when the time comes(if i need to augment) I will always ask you first-I would be willing to say you know more about Parnate then my pdoc.
Well, this is my fourth day and I defintely am feeling a little better- have more energy thats for sure. I'm still waiting for that "wonderful amphetamine effect" I remember that great feeling when I took Panate in '97. I am startig to have some sleep probs-I'm gunna ask my doc for some Lunesta. Take care Willyee, and thank you for all your advice!Tyler
Posted by gardenergirl on February 15, 2006, at 7:01:56
In reply to Re: Parnate and sa--SAMe combination, posted by willyee on February 12, 2006, at 4:06:47
I believe it could also lead to serotonin syndrome, couldn't it?
gg
Posted by willyee on February 15, 2006, at 7:01:56
In reply to Re: Parnate and sa--SAMe combination » willyee, posted by TylerJ on February 12, 2006, at 10:43:04
> That's want I needed to hear-because you are my Parnate "advisor" I trust your judement Willyee and appreciate your advice, I can tell you are a very sincere and concerned friend. I may be a pain in the a** for you for a while-as I'm learning and when the time comes(if i need to augment) I will always ask you first-I would be willing to say you know more about Parnate then my pdoc.
> Well, this is my fourth day and I defintely am feeling a little better- have more energy thats for sure. I'm still waiting for that "wonderful amphetamine effect" I remember that great feeling when I took Panate in '97. I am startig to have some sleep probs-I'm gunna ask my doc for some Lunesta. Take care Willyee, and thank you for all your advice!
>
> TylerNo problem,and parnate users usualy have sleep problems,not all,but the drug is notrious for ruining night time sleep,but at least we currently have some more options.
Posted by TylerJ on February 15, 2006, at 7:01:56
In reply to Re: Parnate and sa--SAMe combination, posted by willyee on February 13, 2006, at 4:21:14
hey willyee are you sure you can take DL-Phenylalanine with Parnate? I went to a vitamin store and talked to a guy who is very knowledgable about AD's even MAOI's, and he said the combination can cause a hypertensive crisis-have you ever taken it w/ parnate, if you have and do,well, then I'm going to try it. How are you doing- what all have you tryed for augmentation. I think I told you this already but thyroid 3, is supposed to be good. And the other day I read the neurontin was one of the best. Hope your doing well! Tyler
Posted by willyee on February 15, 2006, at 7:01:56
In reply to Re: Parnate and sa--SAMe combination » willyee, posted by TylerJ on February 13, 2006, at 19:47:46
I think we got mixed up,i was saying if i were going the natural route id look at either Nadh
or dlpa,but no most aminos not all but a lot dont go with Maois.As far as augmentation,one day id like to make a list,it would be a very long one,but there are many aumentation startegies.In the case where u said Nuerotntion thats another thing,hard to say the BEST cause everyone respnds differently,some use lithium well some dont,its a indivdual thing.
Taurine for example is an amino acid,for me it went well and worked for a while,just not long term.With medication almost all factors are individual.
Posted by TylerJ on February 15, 2006, at 9:58:59
In reply to Parnate and sa--SAMe combination, posted by TylerJ on February 12, 2006, at 2:08:16
Dr. Bob, I'm new at this so a guess I just way for yor answer?
Monte
Posted by honeybee on February 15, 2006, at 15:37:25
In reply to Re: Parnate and sa--SAMe combination, posted by willyee on February 12, 2006, at 4:06:47
Hi, Willyee,
Really? It's that bad? I mean, I was in a horrible depression, worst o-me-life, and after tapering off Cymbalta that I had been on for two weeks (this was two weeks ago) I started taking SAMe at 200 mg. I immediately started feeling better--I think that it made the residual Cymbalta somehow more effective. The effect started to wear off and now I'm at week 2 and at 400. It's not perfect and, yes, I do have some insomnia. But I'm in a much, much better place than I was in early January, when I thought it might be time for me to check into a hospital.
It's not all due to the SAMe, of course. I'm getting acupuncture, am on an herbal preparation from the school where I get the needling, am taking a multivitamin and fish oil, started therapy again yesterday. Call me foolish--I told my pdoc if it's a mistake that I'm making that it's one that I need to make before committing myself to Cymbalta to a year or more--but I'm puzzled that so many studies [I checked out a survey of studies in a Canadian medical journal and Harvard Medical Review] would have been done that are suggestive of its positive effects--this in spite of what I would assume is big resistance from American drug companies. The only reason I'm guessing is that there isn't more resistance is because it really IS so expensive, it isn't covered by insurance, and big Pharma doesn't have much competition to worry about--just for that.
A pity.
Anyway, I'd love to hear what you think.
Thanks.
hb
>
> Bro i am not postive,but if my mind serves me youre just starting parnate correct? No offense but what are you thinking guy,,,,,no u dont want to use samE with parnate,i really dont advise this at all.
>
>
> Explain how u are feeling on parnate,the level of benifit,what is missing,what do you "WANT" from it.......put as much info and let me or someone who knows parnate read it,but at a third day stage i would NOT touch samE
>
> Your still a newborn on it,you havent even yet ensured what diet restrictions u personaly might come across,
>
> If youd like any help post ur dose ur on,how long i think u said 3 days,post again as much as u can think,and ill recomend simply what i would do.
>
>
> As for samE blah,its snake oil,yeSS it crosses the brain,and has been used in Eurpope for years,i know all about it,but to me,.........
>
> This is a nutritnet that is crimanly OVERPRICED,and INSANLY overated.
>
> At its best it will have a stimulant effect,close to caffiene,this is when it works,and you will spend ur money wad getting there.
>
> Now i never speak for everyone i have seen people post they well on it,BUT i also seen many many posts where people come back saying it either dont work,OR caused them to feel maniac,hyper insomnia etc,and it is contradicted in maniac people.
>
>
> Getting away from parnate,if i had to use something in this area,id look into Gotu Kola,DMG,TMG,NADH, or even DLPA.
>
> samE makes me cringe jus thinking of the cost and money i lost on it years ago.
>
> Be safe!
>
>
Posted by TylerJ on February 15, 2006, at 20:31:03
In reply to Re: Parnate and sa--SAMe combination, posted by willyee on February 14, 2006, at 11:54:39
Hey Willyee,
I'm now on 30 mgs. of Parnate and it's definitely working. I feel a lot more social, more energetic, less..much less depressed no anxiety. but it's only been a week and that wonderful Parnate feeling hasn't kicked in no amphetamine effect yet maybe takes a couple of weeks-and my pdoc thinks my body weight is a factor. Hell, I shouldn't complain with all the positive effects I getting. Any advice you can give me will be much appreciated. wish you all the best.
Tyler
Posted by Dr. Bob on February 18, 2006, at 4:55:14
In reply to Re: Parnate and SAMe combination, posted by TylerJ on February 15, 2006, at 9:58:59
> Dr. Bob, I'm new at this so a guess I just way for yor answer?
Sorry, my role here is just administrative...
Bob
Posted by Ilene on February 18, 2006, at 20:16:08
In reply to Parnate and sa--SAMe combination, posted by TylerJ on February 12, 2006, at 2:08:16
> Hey does anyone know if it is safe to take SAMe with Parnate. From what I've read SAMe seems to be a wonderful supplement. I appreciate any info I can get. Thank you.
>
> TylerJI would also like more info on SAMe. My pdoc recommended it, so I've been doing some research, & would like to know about people's responses to it.
I've read it could cause problems if you take it w/ MAOIs, but I don't think there are any documented cases of actual harmful interactions. I believe it is isolated from yeast, which may be the reason for the caution.
I.
Posted by honeybee on February 19, 2006, at 14:15:59
In reply to Re: Parnate and sa--SAMe combination, posted by Ilene on February 18, 2006, at 20:16:08
Ilene,
I'm a newbie, as well, and I don't have much in the way of expertise or understanding of it, so we can both hope that others like Larry Hoover, Blueberry, Linkadge, etc. decide to weigh in. (Pretty please?) Fromwhat I understand, SAM-e is a substance produced by the liver and a key player in the methylation process. Ultimately, this means that SAM-e helps rev up protein and phosolipid metabolism, supposedly (one would help) helping to boost levels of neurotransmitters. SAM-e should be taken with the B-vitamins (specifically B12 and Folic Acid, if I remember correctly) and I've read somewhere else called TMG, which is also a player in methylation and helps SAM-e along. What I've learned I've learned from scavenging the web, my library's electronic digital (online) archives, and throwing a fit at my pdoc's office to get me off of cymbalta (which, despite my gripes, worked just fine for me). I've been on it for a couple of weeks and it's tough to tell.
Tought to tell, you say? Well, I'm on a really low dose (don't ask me why my pdoc started me at the substarting dose, I don't understand it myself), and now I'm on the starting dose. It can be a super expensive route to take for supplementation, but the upside is that it seems to be enabling/helping along your body's regular processes. I envision it as going with the stream's flow as opposed to diverting the stream entirely. Okay, neither of those metaphors really work. At any rate, I might recommend your looking into Fish Oil supplementation in addition to SAM-e. You can find lots more info about the Fish Oil in these chats. Although I haven't noticed much of a difference in particular on the fish oil, I *can* say that in the span of time since I've been taking it--a couple of months--it, combined with acupuncutre, some good multivitamins, and some herbs from my acupuncturist, I'm in a much better place and more functional than I was two months ago, when I felt like I wanted to die. Plus, the fish oil is healthy for you in general.
One thing that lots of people seem to talk about, with the SAM-e is that it can be activating. Best to take it in the AM. Also, there's a book out there on it (Stop Depression Now, by Richard Brown), but I wouldn't really recommend it. You'll find much more extensive information about it on the web.
hb
Posted by Ilene on February 20, 2006, at 23:38:14
In reply to SAMe, posted by honeybee on February 19, 2006, at 14:15:59
Yes, I've gotten that far. I've read a bunch of stuff on the Web. There are some studies being done at Harvard.
What is TMG?
I.
Posted by honeybee on February 24, 2006, at 9:05:16
In reply to Re: SAMe » honeybee, posted by Ilene on February 20, 2006, at 23:38:14
They have new studies being done at Harvard? I hadn't heard...
My pdoc said that it works in about 50% of his patients, about the same as the standard meds. Then, when we discussed how it works, he said that they weren't really sure because there's no money in it, but drew me a lovely diagram of the methylation process and some synapses. Quite a lot of fun, all things considered.
I'm a little on the fence right now. What I know works even better than the SAM-e for me is the acupuncture that I'm getting. Now if I only had the money to get acupuncture every day....In any case, I'm sort of pleased that I'm not on meds right now and seemed to have managed to wrest myself from what I basically should have called and known was a nervous breakdown late last year.
Have you started it? Do you have some other things that you're doing, as well?
Posted by Kath on March 28, 2006, at 20:34:32
In reply to Re: SAMe, posted by honeybee on February 24, 2006, at 9:05:16
Hi honeybee,
do you know which accupuncture points are being treated?
Kath
Posted by honeybee on March 29, 2006, at 15:44:11
In reply to Re: SAMe » honeybee, posted by Kath on March 28, 2006, at 20:34:32
Each week? It depends and is based on my particular constellation of symptoms and type. I have asthma, too, so there have always been some lung points thrown in there. Bafeng (in between each of the toes) is a staple (that's for depression). Some spleen points, I know... Last week, my acupuncturist needled heart 8 (on the palm) to calm my heart. Some really intense points at my brow bone for my sinuses....Some immune points because of allergies and because my immune reflex is intense...
When I'm wanting to do some self treatment, I sometimes use this site: http://med.stanford.edu/personal/pointfinder/. It helps me with specific issues, but I know that they're general and not as geared to me...
Why do you ask? Are you getting acupuncture done too?
hb
Posted by Kath on March 31, 2006, at 20:58:16
In reply to Re: SAMe, posted by honeybee on March 29, 2006, at 15:44:11
Sounds really complex!
I'm not having any right now (it helped with plantar fascitis in the past) but my son just received amazing help for Bell's Palsy & my daughter has MCS (multiple chemical sensitivities) & is receiving it to help that. She has depression also.
Thanks for that site. I'll check it out.
Kath
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