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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 13 of 13. This is the beginning of the thread.
Posted by linkadge on August 3, 2004, at 17:07:36
I've heard that the main effect of SAMe was on dopamine. Does SAMe have any effect on serotonin ??
Linkadge
Posted by oeps7 on August 4, 2004, at 10:09:31
In reply to does SAMe effect serotonin ??, posted by linkadge on August 3, 2004, at 17:07:36
I tried SAM-E once, I am also taking effexor. The SAM-E made me extremely ill, I don't know if it had anything to do with being on effexor at the sam time.
I have found emulsified fish oil works for me - I had stomach trouble on the regular capsules and the emulsified type helps with that a lot.
Anyone experience the same?
Mary
Posted by linkadge on August 4, 2004, at 11:50:25
In reply to Re: does SAMe effect serotonin ??, posted by oeps7 on August 4, 2004, at 10:09:31
I got symptoms of serotonin snydrome when combining SAMe and antidepressants. I got very ill too. This is what lead me to think that SAME effects serotonin.
Linkadge
Posted by oeps7 on August 4, 2004, at 12:38:20
In reply to Re: does SAMe effect serotonin ??, posted by linkadge on August 4, 2004, at 11:50:25
I defnitely agree with you Linkage. Do you take anything else?
Mary
Posted by linkadge on August 4, 2004, at 14:32:56
In reply to Re: does SAMe effect serotonin ??, posted by oeps7 on August 4, 2004, at 12:38:20
I am on and off celexa.
Linkadge
Posted by KaraS on August 4, 2004, at 17:11:59
In reply to Re: does SAMe effect serotonin ??, posted by linkadge on August 4, 2004, at 11:50:25
> I got symptoms of serotonin snydrome when combining SAMe and antidepressants. I got very ill too. This is what lead me to think that SAME effects serotonin.
>
> Linkadge
Linkadge,
I think Larry addressed all that in previous
post(s). Try a search.-K
Posted by linkadge on August 5, 2004, at 7:53:31
In reply to Re: does SAMe effect serotonin ?? » linkadge, posted by KaraS on August 4, 2004, at 17:11:59
do you remember what his final judgement was ???
Linkadge
Posted by KaraS on August 5, 2004, at 12:27:05
In reply to Re: does SAMe effect serotonin ??, posted by linkadge on August 5, 2004, at 7:53:31
> do you remember what his final judgement was ??
>
>
> Linkadge
No sorry. I just remember that he gave us a lot of info on SAM-e. I'll try the search myself since I want to find out more about TMG. I'll get back to you if I find what you're interested in here.
Posted by KaraS on August 5, 2004, at 15:23:52
In reply to Re: does SAMe effect serotonin ??, posted by linkadge on August 5, 2004, at 7:53:31
> do you remember what his final judgement was ???
>
>
> Linkadge
Ironically I found the following post that you made to Larry telling him about SAM-e and serotonin:
Posted by linkadge on August 5, 2004, at 17:42:18
In reply to Re: does SAMe effect serotonin ??, posted by KaraS on August 5, 2004, at 15:23:52
I rememeber writing this after reading an article. I have read some reports that say it affects both serotonin and dopamine, and other reports that say it only affects dopamine.
Now I am not sure which to believe :)
Linkadge
Posted by KaraS on August 5, 2004, at 22:10:02
In reply to Re: does SAMe effect serotonin ??, posted by linkadge on August 5, 2004, at 17:42:18
Thanks for explaining. (I thought you were starting to lose it - like me!)
Posted by linkadge on August 6, 2004, at 7:50:32
In reply to Re: does SAMe effect serotonin ?? » linkadge, posted by KaraS on August 5, 2004, at 22:10:02
Oh don't get me wrong, I am starting to loose it.
I am only 21 and the different meds over the course of the year I have tried have certainly dammaged my brain.
Sometimes I read some of my posts and I am saying to myself, man this guy sounds pretty smart, and then I see my name at the bottom, and I say to myself man I have deteriorated - I can't even understand half the words this "linkage" guy uses ??
Linkadge
Posted by Larry Hoover on August 14, 2004, at 17:19:58
In reply to does SAMe effect serotonin ??, posted by linkadge on August 3, 2004, at 17:07:36
> I've heard that the main effect of SAMe was on dopamine. Does SAMe have any effect on serotonin ??
>
> LinkadgeI've never found a clear answer, honestly. There are two methylation reactions among the major neurotransmitters. The conversion of norepinephrine to epinephrine and the conversion of serotonin to melatonin. As both are "downstream" events, I have trouble understanding the link to serotonin syndrome.
SAMe also methylates DNA, an essential part of the replication to RNA, and all that ensues. But that takes time, days if not weeks, for the effects to be obvious.
I'd happily listen to ideas, if anybody has any.
Lar
This is the end of the thread.
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