Psycho-Babble Medication Thread 1118455

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Paracetamol (acetaminophen) and cannabinoids

Posted by undopaminergic on February 2, 2022, at 12:51:38

Hi all,

I was just reading about NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) and came across this: <<Paracetamol (acetaminophen) ... treats pain mainly by blocking COX-2 and inhibiting endocannabinoid reuptake almost exclusively within the brain, but not much in the rest of the body.>>

Alas, high doses of paracetamol destroy the liver. I wonder if co-administration with the amino acid glutathione would allow higher doses to be used.

-undopaminergic

 

Re: Paracetamol (acetaminophen) and cannabinoids

Posted by undopaminergic on February 2, 2022, at 13:58:34

In reply to Paracetamol (acetaminophen) and cannabinoids, posted by undopaminergic on February 2, 2022, at 12:51:38

https://pubmed.ncbi.nlm.nih.gov/17227290/
Title: Paracetamol: new vistas of an old drug

Full article available:
https://onlinelibrary.wiley.com/doi/epdf/10.1111/j.1527-3458.2006.00250.x

-undopaminergic

 

Re: Paracetamol (acetaminophen) and cannabinoids » undopaminergic

Posted by SLS on February 3, 2022, at 8:00:27

In reply to Re: Paracetamol (acetaminophen) and cannabinoids, posted by undopaminergic on February 2, 2022, at 13:58:34

Excellent contribution.

Excellent information.

Excellent interpretation.

Excellent critical thinking to extend progress forward..

Thank you!

You don't really need my affirmations, but I thought I would give them, anyway. I was motivated to criticize some of your words in the past, as I am now motivated to praise them.

I hope you don't find this insulting.


- Scott

 

Re: Paracetamol (acetaminophen) and cannabinoids » SLS

Posted by undopaminergic on February 3, 2022, at 8:07:01

In reply to Re: Paracetamol (acetaminophen) and cannabinoids » undopaminergic, posted by SLS on February 3, 2022, at 8:00:27

>
> I hope you don't find this insulting.
>

No, I actually appreciated it. I'm glad you're not bitter about the "clash" we had recently.

-undopaminergic


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