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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by Lamdage22 on May 9, 2021, at 2:02:55
Hey guys,
If I was to make an experiment to get off of these two and onto 5-HTP and it failed, might they not work anymore after the pause? I know this happens with MAOI sometimes.
Just want to know how risky my contemplated endeavor is.
Posted by undopaminergic on May 9, 2021, at 8:24:07
In reply to Venlafaxine or Trazodone useless after pause?, posted by Lamdage22 on May 9, 2021, at 2:02:55
> Hey guys,
>
> If I was to make an experiment to get off of these two and onto 5-HTP and it failed, might they not work anymore after the pause? I know this happens with MAOI sometimes.
>
> Just want to know how risky my contemplated endeavor is.What you're worried about can happen with various drugs, such as clozapine. I'm pretty sure it can happen with SSRIs too, so probably it can happen with venlafaxine. I think it is less likely with trazodone, but that's just my intuition.
Given these considerations and especially due to individual variations, you'll have to take a certain risk if you want to try what you're suggesting.
-undopaminergic
Posted by Christ_empowered on May 9, 2021, at 21:39:04
In reply to Venlafaxine or Trazodone useless after pause?, posted by Lamdage22 on May 9, 2021, at 2:02:55
i don't think anyone can answer that question with certainty. :-(
deal is...the drugs do help, some people, in some situations, some times. how's -that- for progress? lol.
but getting down to specifics...what drugs will work, how long treatment should continue, when and if to discontinue, what to do if a taper fails, etc...
almost -0- from the established literature, as best I can tell.
having typed all that, I will say that ongoing exposure to conventional 'antidepressants' seems, intuitively, more problematic than an attempt at abrupt discontinuation in favor of 5-HTP.
long term 'antidepressant' treatment may be a necessary evil for some people, but...some literature would seem to indicate that the end result for a lot of people is more severe low mood swings, longer times of misery, and the need for more and more drugs to stop the depression ("treatment resistant depression"...some theorize this is common, now, because of over use of drugs for extended periods of time).
i have often heard experts say that stopping a neuroleptic would lead to a relapse and then a higher dose of neuroleptic. the truth? as best I can tell, it seems that neuroleptics have their own discontinuation syndromes. clozapine, in particular, can be hell to stop. the typical response to the discontinuation syndrome is use of a neuroleptic. in cases of hospitalization, the trend is to start people on (often excessively) high doses, which are often then maintained on an outpatient basis.
honestly, i think a "drug holiday" might be a good thing. if it works out...the 5-HTP meets your needs...then that'd be a big step towards a more healthful treatment. if it doesn't, then perhaps the psychiatrist in charge of your treatment could re-evaluate the entire combination, and see if perhaps there is a way to do more, with less medication. or not. im clearly not offering any sort of expert opinion or anything, just...I really do hope things work out for you, whatever you decide.
:-)
Posted by Lamdage22 on May 10, 2021, at 3:02:48
In reply to Re: Venlafaxine or Trazodone useless after pause?, posted by Christ_empowered on May 9, 2021, at 21:39:04
Yeah it is certainly more natural than messing around with Neurotransmitter reuptake. The result should be the same as MAOI as far as Serotonin is concerned. And I don't need Dopamine or Adrenaline at all. Just makes me beliggerent. I have reason to be, but it is not smart play right now. I am trying to find somebody who is good in both Orthomolecular and traditional medicine to advise me during the switch.
I am certain that there are at least 5 other nutrients, that help turn 5-HTP into Serotonin. Supplements work in concert with eachother. So yeah, if your levels arent ideal, your results with 5-htp arent ideal.
I think it is funny that traditional mediciners call enhancing the way the body naturally produces Serotonin charlatanry and and contortions at the receptors with foreign substances sound medicine.
They don't say it like that. They say it in a way that makes it sound ridiculous.
Posted by Lamdage22 on May 10, 2021, at 6:57:52
In reply to Re: Venlafaxine or Trazodone useless after pause?, posted by Lamdage22 on May 10, 2021, at 3:02:48
There is a risk though of course. That of one or both of these meds not working again in the event that 5-HTP can't replace them. It is not my first time on Venlafaxine though. And it did work again.
Trazodone is a first though.
Posted by rjlockhart37 on May 12, 2021, at 0:27:48
In reply to Venlafaxine or Trazodone useless after pause?, posted by Lamdage22 on May 9, 2021, at 2:02:55
i would increase the dose, keep increasing it until a response. But .. the doctor only decides that, you coudl mention it to him that you took a pause, now ineffective, speak to him about increasing the dose
Posted by Lamdage22 on May 12, 2021, at 4:06:26
In reply to Re: Venlafaxine or Trazodone useless after pause?, posted by rjlockhart37 on May 12, 2021, at 0:27:48
Nah, increasing the dose makes me anxious. I'm actually cutting the pills in half it as I get a bit of a racing heart after each dose. I surmise that I produce more Serotonin now naturally because I get the right amounts of the right nutrients. Iron was deficient and I have recently fixed it.
This is the end of the thread.
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