Psycho-Babble Medication Thread 1114360

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Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by alexandra_k on April 10, 2021, at 17:52:25

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria?, posted by alexandra_k on April 10, 2021, at 17:41:10

I see how it is, here, with the boards and the managers.

The managers doing the hirings and the firings. The managers deciding whether the doctors will have jobs at all (and how much they will pay them). Whether they will pay them to do the job in the public hospital -- or whether they will pay them more to sub-contract for the job to be done privately. The same doctors. Just about whether they have to work in the public hospital or whether they get to work off-site in a private hospital.

And I see... It's family.

I remember reading something about the A2 milk thing... Before they were merged with / taken over by Fonterra. When they were atually independent. There was a thing about cows producing milk that lacked a protein they wanted to blame lactose intolerance on, or something like that. That had far reaching implications for breeding cows for different traits than had been done before. Lots of money tied up. The potential to move or shift milk from large volume production to less volume higher quality... Someone died. In strange circumstances. Someone young. In a motel or hotel room, I think. Then, a bit later there was a merger.

A couple died recently. Stabbed by someone. Upstanding members of the Indian community. She worked in something to do with Pharmacology. A support services kind of a role. He worked in something to do with Education. Helping people come to NZ to get an education to get into pharmacology (or Medicine). That kind of a thing. This big thing about how they moved into the grammar zone for the schooling and their kid graduated from Massey with an Engineering Degree...

A manager of a hospital in South Auckland died. At home. Her husband (a doctor) was a person of suspicion... He tells the media (even though he has been advised not to speak by his lawyer) this big story about how everything was perfect...

And about how she had been vaccinated twice.

I suppose their whole family had been.

I suppose it's fake news...

But I also suppose that that's what the 'vaccinating front line workers and their families' looks like.

And the doctors who are earning the big bucks working in their private hospitals treating the elite people on the taxpayers public dime... They are teh family of the managers and the board of directors and the like.

And, of course, that's why you get into health. Hospitals. Medicine. TO grubbity grub grub grub up all the resources for you and your family. Helping you, helping you, helping me help myself to you.

Is all there is.

Which is to say there really isn't anything, at all.

I mourn the loss of human potential. All the things that could have been except for the psychopaths ruining the things for us all.

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by alexandra_k on April 10, 2021, at 17:55:38

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria?, posted by alexandra_k on April 10, 2021, at 17:52:25

and that appears to be the only kind of justice that there is, in NZ. that is to say insofar as there was any justice at all. any prevention of re-offending. people die. in allegedly 'mysterious circumstances'. but we are talking about a country that couldn't get it's sh*t together to extradite kim.com in a timely fashion to international community. the judges couldn't do it. really very very genuinely just couldn't seem to do it.

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria? » alexandra_k

Posted by Phillipa on April 10, 2021, at 19:04:07

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria?, posted by alexandra_k on April 8, 2021, at 21:35:52

So you read some of the link I posted then. Those were requested by the government, drug companies, doctors so they would know if the vaccines were safe for authorization. I do think more complaints with Moderna with rashes and feeling cold. As for the immigrants and lower classes not having access to vaccines. Mobile units are going out to talk to the people to reassure them that they are safe. No personal information is given no address just age and name for contact. No papers need to be shown. And the people are getting their vaccines by those they trust some mobile clinics in churches they attend others at the malls. Lots of doctors here just have private practices of their own. My own endo and 89 other doctors left the hospital they were originally employed by to form their own practice together as a team all specialties so they could deliver good patient care. Same insurances are taken by them. So the government does not employ all the doctors. As for the vaccines now Pfizer has submitted to vaccinate children from age 7 - 12 I think it is. Their studies should that in this age group they vaccines are l00% effective in preventing Covid. Phillipa

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria? » Phillipa

Posted by alexandra_k on April 10, 2021, at 21:33:10

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria? » alexandra_k, posted by Phillipa on April 10, 2021, at 19:04:07

> So you read some of the link I posted then.

Yes, I did take a look. Thankyou for posting it.

> Those were requested by the government, drug companies, doctors so they would know if the vaccines were safe for authorization.

I see.

There is supposed to be a way of reporting side-effects of medications.

There wasn't... So Babble Medication Board came to be...

But that is what that is... A notification system, of sorts. The US one...


> I do think more complaints with Moderna with rashes and feeling cold.

Okay. But a great many more people have been given Moderna in the US rather than any other type. I think. So one would expect to see more people registering side-effects. For example, if 2x as many people were given Moderna vaccine then even if the side-effect profile was the same as another kind of vaccine the other kind of vaccine would only have 1/2 as many complaints.

I would take feeling cold and having a bit of a rash over blood clots. Any day of the week :) Unless the rash is indicating bleeding out, of course...

> As for the immigrants and lower classes not having access to vaccines. Mobile units are going out to talk to the people to reassure them that they are safe. No personal information is given no address just age and name for contact. No papers need to be shown. And the people are getting their vaccines by those they trust some mobile clinics in churches they attend others at the malls.

The trouble is... How do we know the vaccines are actually going to these undocumented needy people in the USA rather than... I don't know... Being sold on the black market to the elite officials over in India or South Africa or...

It's easier to get face masks to Canada and South America than to Iowa...

It's more lucrative to sell them on the black market than to give them to undocumented people who are undocumented therefore there are no records.

I think... Moderna... I think they have the capacity to track the vaccines. With the cold store. Maybe more. Maybe by crate. Maybe... Even... Just maybe... By vial.

> Lots of doctors here just have private practices of their own.

Yeah. It's hard and expensive. The set-up costs. Health and safety accreditation. Liability insurance. The expense of buildings. The expense of Medical supplies. Etc. I think that's why most people are stuck a bit working for a major hospital. University hospital. Federal or State hospital. Whaetever. I mean.. You can't just set up an OR in your basement.


> My own endo and 89 other doctors left the hospital they were originally employed by to form their own practice together as a team all specialties so they could deliver good patient care.

89 is a lot.

They were probably all related... Lol. I don't know. They likely all buyed / brought in. LIterally. Distributed the risk.


> Same insurances are taken by them. So the government does not employ all the doctors.

Yeah, I know. There are private hospitals. It becomes an issue, then (to my mind at least) how they source their organs / blood products / plasma etc. To ensure they aren't taking from the PUBLIC system for PRIVATE advantage (that would be corrupt).


> As for the vaccines now Pfizer has submitted to vaccinate children from age 7 - 12 I think it is. Their studies should that in this age group they vaccines are l00% effective in preventing Covid.

Okay. And that's supposed to prevent transmission? Kids weren't getting sick of Covid, I didn't think... So... Uh... Why are we vaccinating them, again?

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by alexandra_k on April 10, 2021, at 21:55:40

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria? » Phillipa, posted by alexandra_k on April 10, 2021, at 21:33:10

I think what NASA meant is that we need to invest in the IT.

I thought as much.

Secure patient records.

Keeping your own data. If you don't... Who will do that for you? You would need to contract it out. Who to? You need to know who is capable.

NZ doesn't have any of it.

We had this booking system of how people were to book places in quarantine. And the system opens up a place sort of seemingly randomly. So people are required to sit by their computers all day hitting 'refresh' on the page waiting for a spot to open up. Which is rediculous, so, of course, people start building bots to do that for them. Or for others. Pay me x and I'll book you a place in quarantine. I mean... That's what the system is asking for -- right?

And of course the system collapses under the weight of the bot spam.

That's also the story of our stock exchange. All the people of the US simply can't buy shares in NZ. Stoppit. Stoppit. Stoppit. Haven't you seen how many wires there are out the back of the computer? Stoppit, already. Attack! We're being attacked!

Will they hire the people capable of botting the system to make a system that doesn't reward bots?

Course not. Everything is just fine. Just okay. We like the people on payroll already. Those people collecting up the megabucks.

It's a pretty boring story.

There are fairly effective HIV medications. Protocols. The trouble is getting the medication to the people who need it... And also... The people who have considerable and significant excess of what they need... Getting those people to cough up for some research and development. Getting those people to cough up so that other people can have medications they need, too.

You give countries aid... Assistance. Supplies etc. And the supplies are given to the wrong people (the people who can afford to pay -- but won't). They're sold on the black market. They're gifted with nepotism...

But there's the technology infrastructure now to track things.

There's the technology infrastructure now to identify the worst offenders and hold them to account / prevent their reoffending. Decommission them. Take them out of action. Get them out of the way.

The people responsible for holding back development.

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria? » alexandra_k

Posted by Phillipa on April 10, 2021, at 23:22:18

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria? » Phillipa, posted by alexandra_k on April 10, 2021, at 21:33:10

Right now the new cases of Covid are in the 20=40 year olds as the older people are fully vaccinated. In order for the schools to open full time and the Universities they must have established herd immunity. And the children are carriers of the virus and now a lot are also getting sick.

Moderna they are saying is stronger has more vaccine concentration in it so thinking of lowering it. Also talk on the medical newsletters I get that they are also thinking of alternating doses of vaccine brands to possibly get the new variants with 5 now all over the states. The UK, Brazilian, African, Indian, and California variants. The rashes if they were spots on hands and soles of feet would indicate thrombocytopenia which has occurred in a few people. Astra Zeneca is not going to give the vaccine to those under 50 due to clots last I heard Johnson & Johnson will be given instead.

The total of the Doctors is 90 didn't count mine. They only see patients in their offices. So they use for anything that needs a hospital one of the two major ones in this area. They must refer their patients to a hospital so they would then be paying the hospital for any procedures operations blood products. Watch tomorrow probably Monday there will be a new change to something to do with the vaccines. And the doctors that do the procedures whether private or one from the hospital will bill the patient separately. Philipa

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria? » Phillipa

Posted by alexandra_k on April 11, 2021, at 0:50:11

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria? » alexandra_k, posted by Phillipa on April 10, 2021, at 23:22:18

> Right now the new cases of Covid are in the 20=40 year olds as the older people are fully vaccinated.

I see.

> In order for the schools to open full time and the Universities they must have established herd immunity. And the children are carriers of the virus and now a lot are also getting sick.

20-40 do you mean, or under 20?

> Moderna they are saying is stronger has more vaccine concentration in it so thinking of lowering it.

Watering it down?

There is a trade-off. Finding a theraputic dose is somewhere between a toxic dose and an ineffective dose. You can look at things at a population level and try and figure out what dose is optimal... Even plugging in a few different parameters, in case it makes a difference. Age band. Gender. Maybe even if one is on one of the most heavily prescribed medications... Like... I don't know... Aspirin. Or a blood thinner. Try and figure what is optimal that way...

But different people are different. Some people have a reactive immune system (indicated by history of allergy). Other people have a more sluggish immune response. Etc.

Ideally... You'd make a clinical... Guestimate. On the basis of the knowledge of mechanisms you get from a combo of science and experience.

But that doesn't mean you have an excuse not to back off when you see symptoms of toxicity.

If they water it down they will likely lower the efficacy (at the population level). But they will also likely lower the risk of symptoms.

Sounds like the rash is thrombocytopenia. The actual course of events seems to be clotting -> thrombocytopenia. So it sounds like part of the same thing. From all of the vaccines.

They are dispensed under 'emergency dispensation' everywhere except NZ, I think. I think that means that everywhere people are giving up the usual legal protections they have. There is an element of experimentation / frontier of knowledge about it. That was justified because... Lots of people have been dying of Covid. So...

All of the vaccines that have been rolled out have less risk associated than the risk that was associated with no vaccination at all.

> Also talk on the medical newsletters I get that they are also thinking of alternating doses of vaccine brands..

Yes. They want to know about mixing and matching different types of vaccine, now. It's a another parameter to collect data on.


>... to possibly get the new variants with 5 now all over the states. The UK, Brazilian, African, Indian, and California variants.

Mmm Hmm. I'm not entirely convinced about all this. I don't understand.

> The rashes if they were spots on hands and soles of feet would indicate thrombocytopenia which has occurred in a few people.

Yeah.

> Astra Zeneca is not going to give the vaccine to those under 50 due to clots last I heard Johnson & Johnson will be given instead.

Yeah. Different countries are setting the age parameter differently. I have heard 60, 50... Different countries value their elderly different...

> The total of the Doctors is 90 didn't count mine. They only see patients in their offices. So they use for anything that needs a hospital one of the two major ones in this area.

I see. Independent consultant with independent consultation rooms.


> They must refer their patients to a hospital so they would then be paying the hospital for any procedures operations blood products.

So they then see the patient in the hospital? Do they do the procedures in the hospital, too?

> Watch tomorrow probably Monday there will be a new change to something to do with the vaccines.

Yes.

> And the doctors that do the procedures whether private or one from the hospital will bill the patient separately. Philipa

So the independent consultants effectively rent rooms (OR's and recovery suites and nursing support and so on) from the hospital?

And insurance smoothes things over for the patient.

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by alexandra_k on April 11, 2021, at 1:33:54

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria? » Phillipa, posted by alexandra_k on April 11, 2021, at 0:50:11

Now all the kids are cuing up for them. The teenagers before prom and high school graduation. It's like some weird coming of age ceremony. So their college experience won't be interrupted -- because they've been vaccinated.

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by alexandra_k on April 11, 2021, at 1:45:44

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria?, posted by alexandra_k on April 11, 2021, at 1:33:54

The issue is: There will be other viruses.

I'm not sure I'm a big believer in these variant strains they claim to have discovered, already...

But the idea is correct, that there will be other viruses.

Just because you have a vaccination from Covid doesn't mean you are immune to all the things.

People know, now, about how sickness is transmitted. That people in close contact transmit disease. That having a lot of people who you are intimate with... Transmits disease. We know about things like HVAC turnover. NZ isn't there, yet, but the US knows. The volume of air in a room that can be filtered and disinfected and returned. We know about clean water. We know about face masks and hand sanitation. And if it isn't Covid anymore it's any number of other things.

And people don't get that. Don't want to get that. Don't want to live their lives respectful of others desire not to catch (or to transmit) infectious disease. Just can't do it. Won't do it. Have had time to become acclimatised. Inculturated. And most simply won't / simply will not.

Most people need the big brother camera on them 24/7 otherwise they simply won't.

Someone to stand over them with a beat-y stick and beat them into compliance.

WOn't do it.

Always looking for the upper hand to profit at the others expense.

Always wanting to play that game. Take the vaccine first. Feel invulnerable. Haha too bad other people lose.

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria? » alexandra_k

Posted by Phillipa on April 11, 2021, at 9:12:08

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria? » Phillipa, posted by alexandra_k on April 11, 2021, at 0:50:11

No the doctors I see refer to the hospital of the patients choice or the one their specific insurance pays for. I have chosen to pay more money and have a medicaire plan that lets me refer myself without even a doctor to any other doctor or hospital anywhere I like. My husband doesn't have medicaire as not 65 yet so has to use the hospital that his insurance he can use. That is obama care insurance plan which he pays for monthly same as I pay for my medicaire and supplemental insurance. I do not know if the docs I use have hospital privilege's Or if they are assigned a doctor who practices within the hospital. Google Tryon Medical Group Charlotte NC. They have about 10 different buildings where different doctors in their practice see patients. So they own/rent separate buildings.

Not water down the vaccine adjust the dose so it isn't as strong. As of now nothing is changing. Phillipa

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by alexandra_k on April 12, 2021, at 17:41:20

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria? » alexandra_k, posted by Phillipa on April 11, 2021, at 9:12:08

I looked up Tryon. Thanks for posting about it.

I was being slightly facecious about 'watering it down'. There isn't any room in the vials for more dilutant to be added.

I see they are saying not to advise people to start taking low dose aspirin prior to vaccine...

I think the jury should be out on that one.

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by alexandra_k on April 12, 2021, at 17:43:52

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria?, posted by alexandra_k on April 12, 2021, at 17:41:20

Of course they also aren't saying to advise people not to start taking low dose aspirin maybe 5 days prior to vaccination, etiher...

They are saying not to take ibuprofin and anti-inflammatory medication -- but those have a different mechanism that plausibly would dampen the immune response...

but aspirin would help prevent the platelet activation. which has nothing to do with immune response (best i can figure) but everything to do with clot formation.

i would have thought. based on 'common knowledge' of mechanisms...

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by alexandra_k on April 12, 2021, at 23:24:03

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria?, posted by alexandra_k on April 12, 2021, at 17:43:52

The link was interesting, Phillipa. I am going to try and apply to get back to North Carolina. One of the things that I really like about the state is how well developed public health is, there. That is something that the state really tries to do. Health. For the people. That's why people move to NC. Education... Health... There is a cancer research / treatment centre at Chapel Hill. That's state cancer care (not private). I'm not saying it is massively accessible or whatever -- but it's something. Right? It's something...

There's some kind of Public-Private partnership thing with Duke and UNC Chapel Hill... And it seems to translate into things in the public sector... Sure, it's about access to patient population for clinical trials... But there seems to be a giving back to the community, too, in that cutting edge treatments are available to the people and they wouldn't be otherwise. Couldn't be otherwise.. Yeah.

The US system is different from the UK or Scotland one that NZ and Australia is based on. We have General Practitioners... You guys have 'family care physicians' or 'internal medicine physicians' (where I think family care is a sub-speciality or something of one way people go or one thing people do with internal medicine).

It was interesting that the CE was saying the company was trying to break them up or split them up (the family medicine people). So the idea was to band or bring them together... In clinics... A few of them... But still group clinics...

I think usually doctors want to be close to other doctors for second opinions and the like. So they can ask for help when they need it. And so they can focus more on the job more and delegate things.. IT systems and administration tasks and so on...

I hear sometimes details about how things are funded in the US and my eyes start to glaze over. Which is why they offer continuing education credits to people to follow along...

SOmething about proceduralists getting all the billings therefore glory. About how that has not been good for family care medicine... It has not been good for patient centred management of more chronic conditions where one needs to be mindful of how symptoms and medications interact... And the persons history of response to medications or combinations of medications.

He was saying this new model (getting them out of the hospitals and closer to the communities) was trying to allow them to have more lengthy consulations without pressure for (likely unnecessary) procedures to be billed...

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by alexandra_k on April 13, 2021, at 17:30:37

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria?, posted by alexandra_k on April 12, 2021, at 23:24:03

I see J&J vaccine delievery has been halted with less than 1 per million having the clotting thing.

They say 'it is a weird clotting thing and the ususal treatment for clots isn't effective'.

Yeah.

They said... *MONTHS* ago that it was like Heparin induced thrombocytopenia which is a known thing where platelets activate causing clots and then platelets are removed or all tied up so the person starts to bleed out (thrombo means thrombosis meant clot and cytopenia means too few cells in this case platelets).

They said... *MONTHS*** ago... really really really early on it was like Kawasaki disease but in adults. Kawasaki disease is a bit of a weird hodge podge but the main treatment for it seems to be what unites it. Aspirin. It's weird because normally or usually you don't give aspirin to children because of the risk of them developing Reyes syndrome...

So why halt the J&J vaccine?

NZ is getting around to banning live animal exports.

Overseas places like their meat really really really really really really really fresh so we export them live so the meat arrives really really fresh. the conditions on the ships are appalling. Every occasionally something goes wrong and thousands upon thousands of cattle drown horrible deaths...

My question is...

They say that thrombosis is something that happens generally in the general population. ANd to start with they thought that the cases of it that they were finding in people who had had AstraZenica vaccine was no more than would usually be the case in the population.

But then... So... Why aren't there any cases being reported with the mRNA vaccines then? Are the mRNA vaccines having this wonderfully fortuitous side effect of preventing thrombosis across the board? Really? Without increasing the risk of spontaneously bleeding?

That really doesn't seem likely.

So there should be people with thrombotic events who have been given mRNA vaccines.

Why aren't they being reported?

That suggests very very strongly dodgey reporting of stats in the mRNA vaccines. That they aren't saying how manhy of their peopel they are finding with clots.

If there weren't any it would be a miracle.

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria? » alexandra_k

Posted by Phillipa on April 13, 2021, at 18:02:24

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria?, posted by alexandra_k on April 13, 2021, at 17:30:37

There is a Miami ob-gyn doctor that received the Pfizer vaccine in the beginning and he had the classic signs at home that he had a platelet problems small red spots on bottom of his feet and palms of his hands. Took himself to the ER. Testing showed he had absolutely no platlets so I don't think they knew how to treat him then. His wife has or had a facebook profile page. Never looked for it. She announced his death and the fact that he was pro vaccine so that is how it got out. He was supposed to have some treatment to try and restore his platlets but he died that night a few days later. Wonder who has money in Pfizer vaccine? Google the Miami ob-gyn doctor that had the pfizer vaccine. The FDA at the time said they would investigate it but nothing was ever said about it again. Phillipa

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by Phillipa on April 13, 2021, at 18:09:49

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria? » alexandra_k, posted by Phillipa on April 13, 2021, at 18:02:24

The Miami ob-gyn doctor that died after Pfizer vaccine. Didn't realize that was two weeks later also. hope this link copied.

https://www.miamiherald.com/news/local/community/miami-dade/miami-beach/article248337525.html

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by Phillipa on April 13, 2021, at 18:36:21

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria?, posted by Phillipa on April 13, 2021, at 18:09:49

I wonder if this is why the focus is on the J&J vaccine? Check this out just came in my RN newsletter.


JERUSALEM (Reuters) - The coronavirus variant discovered in South Africa may evade the protection provided by Pfizer/BioNTech's COVID-19 vaccine to some extent, a real-world data study in Israel found, though its prevalence in the country is very low and the research has not been peer reviewed.

The study, released ahead of peer review on the medRxiv website on Friday, compared almost 400 people who had tested positive for COVID-19, 14 days or more after they received one or two doses of the vaccine, against the same number of unvaccinated patients with the disease.

It matched age and gender, among other characteristics.

The South African variant, B.1.351, was found to make up about 1% of all the COVID-19 cases across all the people studied, according to the study by Tel Aviv University and Israel's largest healthcare provider, Clalit.

But among patients who had received two doses of the vaccine, the variant's prevalence rate was eight times higher than among the unvaccinated - 5.4% versus 0.7%.

This suggests the vaccine is less effective against the South African variant, compared with the original coronavirus and a variant first identified in Britain that has come to comprise nearly all COVID-19 cases in Israel, the researchers said.

"We found a disproportionately higher rate of the South African variant among people vaccinated with a second dose, compared to the unvaccinated group. This means that the South African variant is able, to some extent, to break through the vaccine's protection," said Tel Aviv University's Adi Stern.

The researchers cautioned, though, that the study only had a small sample size of people infected with the South African variant because of its rarity in Israel.

They also said the research was not intended to deduce overall vaccine effectiveness against any variant, since it only looked at people who had already tested positive for COVID-19, not at overall infection rates.

Pfizer declined to comment on the Israeli study.

Pfizer and BioNTech said on April 1 that their vaccine was around 91% effective at preventing COVID-19, citing updated trial data that included participants inoculated for up to six months.

They have been testing a third dose of their shot as a booster, and have said they could modify the shot to specifically address new variants if needed.

In respect to the South African variant, they said that among a group of 800 study volunteers in South Africa, where B.1.351 is widespread, there were nine cases of COVID-19, all of which occurred among participants who got the placebo. Of those nine cases, six were among individuals infected with the South African variant.

Some previous in vitro studies have indicated that the Pfizer/BioNTech shot was less potent against the B.1.351 variant than against other variants of the coronavirus, but still offered a robust defence.

VARIANT IS NOT WIDESPREAD

While the results of the study may cause concern, the low prevalence of the South African strain was encouraging, according to Tel Aviv University's Stern.

"Even if the South African variant does break through the vaccine's protection, it has not spread widely through the population," said Stern, adding that the British variant may be "blocking" the spread of the South African strain.

Almost 53% of Israel's 9.3 million population has received both Pfizer doses. Israel has largely reopened its economy in recent weeks while the pandemic appears to be receding, with infection rates, severe illness and hospitalizations dropping sharply.

About a third of Israelis are below the age of 16, which means they are still not eligible for the shot.

SOURCE: https://bit.ly/2QlPsir medRxiv, online April 9, 2021.

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria? » Phillipa

Posted by alexandra_k on April 15, 2021, at 19:09:29

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria? » alexandra_k, posted by Phillipa on April 13, 2021, at 18:02:24

> Testing showed he had absolutely no platlets so I don't think they knew how to treat him then.

You give him platelets if you have got platelets to give him. That is to say a blood transfusion. There are different blood products... But there's definately a blood product that contains platelets. To be given to people who are very very low on platelets. Even regular blood. For blood transfusion. Would have platelets in it.

> He was supposed to have some treatment to try and restore his platlets but he died that night a few days later.

I see. That's sad. Finding he has NO platelets is... The main complication of no platelets (or very very low platelets) is bleeding into the brain. Something like that could have happened. I don't know how quickly things set in. How much time there is for a medical intervention to be effective. I don't know how widely available blood transfusions or platelet replacement therapy is for people if they present like that to the ER.

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by alexandra_k on April 15, 2021, at 19:27:49

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria?, posted by Phillipa on April 13, 2021, at 18:36:21

The link copied but I need to disable my ad block to view it -- and I don't know how to disable / reenable it. And mostly it serves me so very very well that I don't look at things that require me to disable it...

> JERUSALEM (Reuters) - The coronavirus variant discovered in South Africa may evade the protection provided by Pfizer/BioNTech's COVID-19 vaccine to some extent, a real-world data study in Israel found, though its prevalence in the country is very low and the research has not been peer reviewed.

A study with a very low sample size is more likely to be a chance finding. If you flip a fair coin 4x then you are more likely to get 75% heads than if you flip a coin 4x 4x.

I think... I think that's true. Now I'm worried. The gamblers fallacy is when you think the outcome of previous flips bias or alter the odds on the next. So... Thinking a series of heads makes tails more likely than 50%. Eep.

There could be a single family that was exposed to high viral load after their vaccination. WIth a small sample size. Or a particular community that congregates at a particular church or something. As the only source of that variant in Israel.

> The researchers cautioned, though, that the study only had a small sample size of people infected with the South African variant because of its rarity in Israel.

Yes.

> Pfizer declined to comment on the Israeli study.

Yes.

> They have been testing a third dose of their shot as a booster, and have said they could modify the shot to specifically address new variants if needed.

Yes. I wondered. I wonder if people who have had J&J may be invited to take a second dose of... Something. At some point. We don't know. We (some people anyway) are learning...

___________________

I am curious about why there aren't any reports of blood clots with Pfizer. I mean... Normally people get blood clots occasionally. That's something that happens. So to start with they thought the ones after AstraZenica (and maybe now Janssen / J&J) were just what happens sometimes. Nothing to do with the vaccine at all.

Then there was something to do with how they weren't really sure about the background rate. They weren't really sure how frequent or prevalent clots were to be able to say how many more of them were occurring in people who had those vaccines.

Which is weird. I am not sure the source of the confusion there.

But now... My question is: How many people with Pfizer are having blood clots? How many? None?

What?

Pfizer discovered a 100 per cent effective prevention for blood clots? IN a vaccine form? Really? WOW!!!

Nobody is saying that (and presumably it's not plausible). So... Why isn't Pfizer reporting how many people have had blood clots after teh Pfizer vaccine?

I'm... Thinking, now, that what is being reported is just a sort of... Con-munications. To try and motivate people taking different vaccines instead of thinking one is the best. The Pfizer one was teh mRNA vaccine for the people (they are trying to associate the label of AstraZenica with that -- but no. That's Pfizer. The cheaper variant of ModeRNA).

Sigh

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by alexandra_k on April 15, 2021, at 19:36:13

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria?, posted by alexandra_k on April 15, 2021, at 19:27:49

To be fair, it is a particular kind of blood clotting problem that is different from the usual garden variety thrombosis that people tend to get.

The combination of clots / thrombosis together with low platelets.

I think that is atually very rare. Though... To be fair... That is also something likely to be under-reported. That is to say, I don't know that the people in the ambulance or the ER or whatever would find that / report of it / identify it. Etc. I don't know...

I say that because Kawasaki disease is listed... But that's something that affects children. Leading cause of acquired acute cardiac failure (resuting in death) in children. So that's something to watch out for in children because, I believe, with supportive treatment (platelets and high dose aspirin -- which usually you don't give to kids) you can help tehm through the crisis and then tehy recover.

But the book doesn't say that there is a comparable phenomenon in adults. So... It looks like adults don't get that.

But there is heparin induced thrombocytopenia. And there teh drug heparin is thought to be the case...

But in Kawasaki disease the cause is... Well it seems to be a hodge podge of things. It can be induced by a virus. A vaccination...

It does seem to be the same thing. Clinically relevantly the same thing.

But it does seem pretty rare. But they were finding it early on with Covid. When I was trying ot get a handle on what people (with Covid) were dying of, exactly...

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by alexandra_k on April 15, 2021, at 19:47:02

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria?, posted by alexandra_k on April 15, 2021, at 19:36:13

Did you know that blood is an organ?

Did you know that there are all these laws on organ harvesting? Selling organs? That kind of thing...

It's interesting from a public-private sort of a thing...

I mean, on the one hand, a lot of work needs to go into preparing things. That's the case with biology generally. I mean... The work that goes into collecting antibodies from blood donations and then purifying them, getting rid of the other things in the sample that could be harmful. Then storing them. All the work... All the labor. All the costs and the technologies involved in it being possible to do anything with them at all...

But some people are organ donors...

And some people are organ recipients...

And some people give 'donations' to St Johns so that they are delivered to the hospital in a timely fashion and some other people don't... So... St John's sends ambulance officers into their homes (if teh officers arrive at all) to bully them out of this silly notion of going anywhere... Or St John's involuntarily detains them in the back of the ambulance in the name of the ER being 'full' or...

Our blood goes to Australia for processing. Melbourne. I don't know what comes back. I don't know where it resides.

I went to a talk about how when there seemed to be an opportunity to aquire blood they would take it. That is to say if someone presented in crisis and they may need blood units they would ask for blood units for them. Teh units would not arrive in time for them to use them on that patient... But now they would be arrived. And therefore stored locally. For someone else to use...

The private hospitals have blood units. I suppose.

Who are the donors, then?

I think... I'm not actually sure how it goes in NZ. I think they are sort of wanting it to be 'invitation only'. That is to say they have some drives... But mostly there are a small group of donors who regularly donate. I suppose with the expectation (reasonable or not I don't know) that blood products may be available to them if they need them.

There was like one lady who had... I think she had 2 kidney transplants that failed and then her brother was going to donate his for a 3rd attempt.

I don't know how she gets to have 3 in the public sector while so many other people never get 1.

We have a lot of corruption in our public hospitals. A lot of using public resources for private advantage.

I do worry in the US I think lately a lot of private hosptials have become interested in public things lately because they are seeing a potential to... Really use public things for private advantage. Immunisations. But more than that. Blood products. But why stop there? Other organs... And so on...

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by alexandra_k on April 16, 2021, at 19:28:15

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria?, posted by alexandra_k on April 15, 2021, at 19:47:02

it's just back around, again, to blood plasma. as a treatment.

And the black market for that. Of course.

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria? » alexandra_k

Posted by Phillipa on April 17, 2021, at 18:47:20

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria? » Phillipa, posted by alexandra_k on April 15, 2021, at 19:09:29

As you know from being in CH the hospitals all have blood banks in them to use when blood or platelets or plasma needed. Lots of people donate blood here. I did twice when much younger in early 20's problem is my ob-gyn saw me and got really upset with me cause I have been anemic with first pregnancy. Long story short the second time the blood showed I was anemic again so was sent away without donating blood.

Now with the Johnson & Johnson vaccine on pause the one I had with husband I wonder if cause older not at risk of the bleeding out? Phillipa

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by alexandra_k on April 17, 2021, at 23:01:24

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria? » alexandra_k, posted by Phillipa on April 17, 2021, at 18:47:20

I didn't know about NC.

I did try and donate once in NZ and was turned away for anemia, also. I was younger, then, with heavy menstrual flow. You lose a lot of iron menstruating.

> Now with the Johnson & Johnson vaccine on pause the one I had with husband I wonder if cause older not at risk of the bleeding out? Phillipa

I think the idea was that older people are at risk of blood clot anyway so no increase in that age group... Whereas younger people are less likely to have blood clots so an increase in that age group.

That was the only thing that made sense to me, of what they were saying.

I want to know how many people with Moderna and Pfizer are having the clots / bleeding.

The clots / bleeding was less than 1 in 1 million people, Phillipa.

There are... 4 Million people in NC? But how many of them had the J&J vaccine? 1 quarter? So maybe 1 person got the clotting thing? In a state with a really good health system and a lot of blood units??

 

Re: Why Did ASTRA ZENECA change name to Vaxzevria?

Posted by Lamdage22 on April 28, 2021, at 22:23:40

In reply to Re: Why Did ASTRA ZENECA change name to Vaxzevria? » alexandra_k, posted by Phillipa on April 17, 2021, at 18:47:20

I am receiving my Biontech/Pfizer shot tonight. Probably not going to lift weights until Monday, because I do so quite intensively. I don't need myocarditis.


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