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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by rovers95 on January 29, 2020, at 9:43:14
I've just started taking mirapex for bipolar (2) depression. Up to 2mg now. Just wondering what people have found as a therapeutic dose...and now long it takes to kick in?
Thanks in advance
Posted by Lamdage22 on January 29, 2020, at 12:32:45
In reply to Mirapex for Depression - experiences, posted by rovers95 on January 29, 2020, at 9:43:14
Dopamine is so sweet if you are not prone to psychosis.
Posted by undopaminergic on January 30, 2020, at 3:02:04
In reply to Mirapex for Depression - experiences, posted by rovers95 on January 29, 2020, at 9:43:14
> I've just started taking mirapex for bipolar (2) depression. Up to 2mg now. Just wondering what people have found as a therapeutic dose...and now long it takes to kick in?
>
> Thanks in advance
>
>For me pramipexole (Sifrol, Mirapex) kicked in almost immediately. It is the only drug that has helped for my anhedonia. I enjoyed real pleasure from watching movies, eating, and drinking. Colours were more vivid and music sounded almost sublime.
The effects didn't last. I did not try very high doses. Maybe I gave up on it too easily. The tolerance did not go away after taking a break from the drug.
-undopaminergic
Posted by undopaminergic on January 30, 2020, at 3:04:13
In reply to Re: Mirapex for Depression - experiences, posted by Lamdage22 on January 29, 2020, at 12:32:45
> Dopamine is so sweet if you are not prone to psychosis.
Have you tried taking dopaminergics and increasing the dose of neuroleptics as needed? From what I've read, this works well with amphetamines, but I'm not sure about other dopaminergics.
-undopaminergic
Posted by Lamdage22 on January 30, 2020, at 10:58:35
In reply to Re: Mirapex for Depression - experiences, posted by undopaminergic on January 30, 2020, at 3:04:13
There is no increasing neuroleptics at 800mg Seroquel and 25mg Zyprexa. Still get anxious at times.
> > Dopamine is so sweet if you are not prone to psychosis.
>
> Have you tried taking dopaminergics and increasing the dose of neuroleptics as needed? From what I've read, this works well with amphetamines, but I'm not sure about other dopaminergics.
>
> -undopaminergic
>
Posted by sigismund on January 30, 2020, at 19:46:15
In reply to Re: Mirapex for Depression - experiences, posted by Lamdage22 on January 30, 2020, at 10:58:35
Any feelings about piribedil? I liked that.
Never taken Mirapex.
Posted by rjlockhart37 on January 31, 2020, at 2:26:33
In reply to Re: Mirapex for Depression - experiences, posted by sigismund on January 30, 2020, at 19:46:15
i've read of some antidepressant effects, it does increase dopamine, but when its suddenly stopped heard people had stories of depression and sadness, due to no agonist of receptor
Posted by pedr on February 7, 2020, at 4:42:27
In reply to Mirapex for Depression - experiences, posted by rovers95 on January 29, 2020, at 9:43:14
> I've just started taking mirapex for bipolar (2) depression. Up to 2mg now. Just wondering what people have found as a therapeutic dose...and now long it takes to kick in?
>
> Thanks in advance
>I had high hopes for pramipexole as I have severe TRD and seemingly respond best to dopaminergic medications. However I felt no response whatsoever that I could ascertain, I was pretty devastated.
Pete
Posted by rovers95 on February 9, 2020, at 17:28:35
In reply to Re: Mirapex for Depression - experiences » rovers95, posted by pedr on February 7, 2020, at 4:42:27
> > I've just started taking mirapex for bipolar (2) depression. Up to 2mg now. Just wondering what people have found as a therapeutic dose...and now long it takes to kick in?
> >
> > Thanks in advance
> >
>
> I had high hopes for pramipexole as I have severe TRD and seemingly respond best to dopaminergic medications. However I felt no response whatsoever that I could ascertain, I was pretty devastated.
>
> Pete
>
>Thanks Pete, how high did you go, dosage wise?
Posted by pedr on February 13, 2020, at 18:45:25
In reply to Re: Mirapex for Depression - experiences » pedr, posted by rovers95 on February 9, 2020, at 17:28:35
> > > I've just started taking mirapex for bipolar (2) depression. Up to 2mg now. Just wondering what people have found as a therapeutic dose...and now long it takes to kick in?
> > >
> > > Thanks in advance
> > >
> >
> > I had high hopes for pramipexole as I have severe TRD and seemingly respond best to dopaminergic medications. However I felt no response whatsoever that I could ascertain, I was pretty devastated.
> >
> > Pete
> >
> >
>
> Thanks Pete, how high did you go, dosage wise?According to my notes, 0.125mg.
This is the end of the thread.
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