Shown: posts 1 to 13 of 13. This is the beginning of the thread.
Posted by Lamdage22 on June 27, 2019, at 23:38:51
Hey guys,
right now i take 37.5 mg Venlafaxine at nighttime. I was thinking to switch to morning time and 75mg. I also take 75mg of Trazodone in the morning. Will that work?
Posted by Christ_empowered on June 28, 2019, at 10:16:13
In reply to Raising Effexor?, posted by Lamdage22 on June 27, 2019, at 23:38:51
hi. id be mostly concerned about raising blood levels of the neuroleptics. do you have any EPS, akathisia, etc.?
the prozac I take has -definitely- increased the effects of the abilify. im on a moderate dose, so...i roll with it, mostly because the prescriber didn't seem gung ho about a dosage reduction...
but with the doses of what you're taking, plus the sedation...id be concerned, most definitely.
sorry to be a bummer bob. psychiatrists are well aware the antidepressants raise neuroleptic blood levels...i read a brief paper once that offered the explanation that what antidepressant treatment 'really' does in schizophrenia is alleviate mood problems by boosting neuroleptic levels. ugh. shrinks.
good luck to you.
Posted by Lamdage22 on June 28, 2019, at 12:53:32
In reply to Re: Raising Effexor?, posted by Christ_empowered on June 28, 2019, at 10:16:13
I have never heard of this.
Posted by Lamdage22 on June 28, 2019, at 13:11:36
In reply to Re: Raising Effexor?, posted by Lamdage22 on June 28, 2019, at 12:53:32
I think that is specific to Prozac
Posted by Lamdage22 on July 20, 2019, at 9:59:34
In reply to Re: Raising Effexor?, posted by Lamdage22 on June 28, 2019, at 13:11:36
So I have decided to abort the trial. I didn't like near anorgasmia.
Posted by SLS on July 22, 2019, at 13:25:27
In reply to Trial failed, posted by Lamdage22 on July 20, 2019, at 9:59:34
> So I have decided to abort the trial. I didn't like near anorgasmia.
I found that anorgasmia improved with continued trials of Nardil and Trintellix - about three months. I don't recall having problems with Effexor. It's a hell of a trade-off to have to make, but I wouldn't hesitate to lose my ability to orgasm if it meant gaining my freedom from depression and joining the world of the living without torment.
- Scott
Posted by Lamdage22 on July 23, 2019, at 9:27:59
In reply to Re: Trial failed, posted by SLS on July 22, 2019, at 13:25:27
Well, freedom from depression is not what Venlafaxin does for me.
> > It's a hell of a trade-off to have to make, but I wouldn't hesitate to lose my ability to orgasm if it meant gaining my freedom from depression and joining the world of the living without torment.
Posted by Lamdage22 on July 23, 2019, at 9:29:16
In reply to Re: Trial failed, posted by Lamdage22 on July 23, 2019, at 9:27:59
I agree, if you were to feel serene enough so you dont need sex.
Posted by Lamdage22 on July 24, 2019, at 12:59:46
In reply to Re: Trial failed, posted by Lamdage22 on July 23, 2019, at 9:29:16
I have my doubts that any drug out there right now can do that for me what you speak about. You are talking complete remission. I am not that lucky, unfortunately.
Posted by SLS on July 26, 2019, at 10:04:33
In reply to Re: Trial failed, posted by Lamdage22 on July 24, 2019, at 12:59:46
> I have my doubts that any drug out there right now can do that for me what you speak about. You are talking complete remission. I am not that lucky, unfortunately.
Keep and eye out for zuranolone (SAGE-217). September maybe?. It is an analogue of brexanolone (Zulressa) that is to be taken orally. There is no antidepressant out there that resembles this drug. It works on GABA as a positive allosteric modulator of the GABA-A receptor.
Zuranolone continues to be studied for post-partum depression, major depressive disorder, and bipolar depression. Reports look good so far.
- Scott
Posted by Lamdage22 on July 26, 2019, at 21:07:42
In reply to Re: Trial failed, posted by SLS on July 26, 2019, at 10:04:33
will do, thanks, Scott!
Posted by Lamdage22 on July 26, 2019, at 21:40:34
In reply to Re: Trial failed, posted by Lamdage22 on July 26, 2019, at 21:07:42
I don't exactly have postpartum Depression but I will mention it to my psychiatrist. I wonder if there is an issue with driving?
Posted by Lamdage22 on July 28, 2019, at 6:58:55
In reply to Re: Trial failed, posted by Lamdage22 on July 26, 2019, at 21:40:34
So there is the fact that it isn't approved for major depression AND the fact that it isn't released on the European market yet. I have a laid back psychiatrist but I don't know if he is that laid back. Whats it gonna cost?
This is the end of the thread.
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