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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by Ruuudy on March 29, 2019, at 0:31:36
Interesting.
Propofol for Treatment-Resistant Depression
https://www.ncbi.nlm.nih.gov/pubmed/30260415So I'm scheduled for my first-ever colonoscopy in a few weeks and I'm researching the various anaesthetics that might be used, wondering if ketamine could be one of those involved. It's unlikely that ketamine would be used; most likely a combo sedative with Propofol as one of the ingredients. Out of curosity, I Googled "Propofol for depression" and it came back with some surpring results.
Almost 6 years ago, I made a trip to the ER with a shattered wrist from a skateboarding accident. I had to have a reduction procedure that night to realign my wrist before the surgery I had the following morning. I recall them saying I was going to be put in conscious sedation and that I would be half-awake but be able to hear the doctors talking. I do remember feeling like I was floating above the scene hearing what they were talking about.
I've been trying & trying to get ahold of the medical records from that visit to learn what anaestheia was used that night.
I am hoping to hear that ketamine was used - that would help seal my choice to proceed with IV ketamine treatments.Rudy
Posted by rjlockhart37 on March 29, 2019, at 1:19:13
In reply to Propofol for Treatment-Resistant Depression, posted by Ruuudy on March 29, 2019, at 0:31:36
yeah, but profofol is ... it puts you out, its good for emergency sleep if you have severe insomnia, but yeah they wrote it has antidepressant properties, but i guess that would be during the time it was active? during a sleep state....but they also wrote using it with electroconvultant therapy
Posted by Hugh on March 29, 2019, at 13:15:27
In reply to Propofol for Treatment-Resistant Depression, posted by Ruuudy on March 29, 2019, at 0:31:36
I doubt you were given ketamine.
I read that study about propofol for depression. Several years ago, I was given propofol for surgery. For days after my surgery, I was in an unusually good mood. At the time, I attributed it to the relief I felt about not having to worry about the surgery anymore. Now, I think propofol might have contributed to my good mood.
Posted by bleauberry on March 30, 2019, at 10:37:36
In reply to Propofol for Treatment-Resistant Depression, posted by Ruuudy on March 29, 2019, at 0:31:36
I think the best thing for treatment resistant depression is a second opinion by an LLMD. Psychiatrists do not generally heal people or get them a lot better from the psychiatric symptoms, but LLMDs do.
The goal should be to restore you to the person you were before you got sick. Psychiatrists don't do that. Once in a blue moon they do get lucky. Sort of like a casino. And that's what keeps patients trying over and over and over again, sort of like the gambler looking to get lucky.
Get an LLMD if you really want your symptoms to get better or totally be gone.
Posted by linkadge on March 30, 2019, at 14:10:25
In reply to Propofol for Treatment-Resistant Depression, posted by Ruuudy on March 29, 2019, at 0:31:36
My grandfather died about 20 years ago, but had surgery a few years prior to his death. At the time, he was suffering from depression, but showed a significant improvement after the surgery.
The doctors at the time told us 'that can happen'. So apparently, people knew (albeit anecdotally) even back then that some of the anesthetics can improve depression symptoms.
Linkadge
Posted by baseball55 on March 31, 2019, at 17:48:07
In reply to Re: Propofol for Treatment-Resistant Depression, posted by linkadge on March 30, 2019, at 14:10:25
Propofol is what killed Michael Jackson. It can only be used under constant anesthesiologist observation, since it wears off in about 15 minutes and needs to be dosed constantly in surgery. And it knocks you out. Not conscious sedation (I used it for a knee replacement last summer).
Colonoscopy - usually versed and fentanyl. That's what they gave me when I had one in the spring/.
This is the end of the thread.
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