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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by Mtom on September 26, 2016, at 7:38:52
Very summarized history (long as this post this). Mid-aged female, started experiencing depression suddenly years ago. Last 3 years worse. Can't take antidepressants or supplements with similar properties eg 5HTP - agitation/anxiety (sometimes severe), mood swings, brain-fog, even serotonergic reactions. Scarier than the depression. Tests years ago showed Stage 1 Liver P450 enzyme system not functioning correctly, may be reason for intolerance.
Sleep issues have been increasing. Dr. prescribed very low dose Trazodone for sleep only, says dosage (25 to 50 mg) too low for antidepressant effect (but remember I'm super-sensitive). Been reading it is an atypical antidepressant. Should I risk it? What are typical and rarer side effects? Don't want to feel worse. Why have I never heard it mentioned by Doctor or others I've discussed anti-depressants with?
Posted by J Kelly on September 26, 2016, at 10:35:50
In reply to What's Trazodone, why I've never heard of it....., posted by Mtom on September 26, 2016, at 7:38:52
Hello.
I only have a partial answer for you but I do have experience with Trazadone. I, too, was prescribed it as a sleep aid.
> Very summarized history (long as this post this). Mid-aged female, started experiencing depression suddenly years ago. Last 3 years worse. Can't take antidepressants or supplements with similar properties eg 5HTP - agitation/anxiety (sometimes severe), mood swings, brain-fog, even serotonergic reactions. Scarier than the depression. Tests years ago showed Stage 1 Liver P450 enzyme system not functioning correctly, may be reason for intolerance.
I don't respond well to standard a/d's either. SSRI's in particular cause me to feel very anxious with no benefit.
>
> Sleep issues have been increasing. Dr. prescribed very low dose Trazodone for sleep only, says dosage (25 to 50 mg) too low for antidepressant effect (but remember I'm super-sensitive). Been reading it is an atypical antidepressant. Should I risk it? What are typical and rarer side effects? Don't want to feel worse. Why have I never heard it mentioned by Doctor or others I've discussed anti-depressants with?I found Trazadone to be very effective for sleep. However, I always felt like I had a hangover the next morning. I had to ditch it. As far as its popularity as an a/d, I hear its not often used for that purpose as its not very effective. That may be why you haven't heard of it.
Good luck!
Jade
Posted by rjlockhart37 on September 26, 2016, at 13:36:20
In reply to Re: What's Trazodone, why I've never heard of it..... » Mtom, posted by J Kelly on September 26, 2016, at 10:35:50
trazadone is notoriously used in psych hospitals as a first choice sleep aid, it's an antidepressant but it works more on making you sleepy......some people do take trazodone in the day as antidepressant, but it' sedation can cause difficulty in working, it depends on how the person responds to it....
it comes in 50mg-300mg and mainly is used at night as a sleep aid......it's not euphoric, just suttles you to want to go to sleep.....
Posted by Poet on September 26, 2016, at 16:20:12
In reply to What's Trazodone, why I've never heard of it....., posted by Mtom on September 26, 2016, at 7:38:52
Hi MTom,
Trazodone worked well for me for a few months for sleep then it stopped working. Pdoc switched me to a very small dose of Seroquel for sleep after I left her a rambling message after I was up for 36 hours.
Good luck.
Poet
Posted by Christ_empowered on September 26, 2016, at 17:08:17
In reply to What's Trazodone, why I've never heard of it....., posted by Mtom on September 26, 2016, at 7:38:52
the only person I've known on trazodone for depression was a lady with schizophrenia...supposed to help negative symptoms or something. I dunno.
As a sleep aid, I think its fairly standard. I don't like it myself...the sleep wasn't refreshing in the least, I felt drugged the next day, whine whine whine. Some people swear by it for insomnia.
Posted by Lamdage22 on September 27, 2016, at 6:18:52
In reply to Re: What's Trazodone, why I've never heard of it....., posted by Christ_empowered on September 26, 2016, at 17:08:17
i take 75mg in the morning. It does not make me tired anymore and i cant take more.
Posted by SLS on September 27, 2016, at 6:49:41
In reply to Re: What's Trazodone, why I've never heard of it....., posted by Lamdage22 on September 27, 2016, at 6:18:52
> i take 75mg in the morning. It does not make me tired anymore and i cant take more.
In what ways does Seroquel at a dosage of 1000 mg/day help you that lower dosages do not?Do you think that replacing the trazodone with Remeron might help with sleep and augment Effexor at the same time?
- Scott
Posted by Mtom on September 27, 2016, at 7:52:24
In reply to Re: What's Trazodone, why I've never heard of it....., posted by Lamdage22 on September 27, 2016, at 6:18:52
Hi Lamdage - if you're not using it for a sleep aid, are you using it for its antidepressant properties? Is it working?
Posted by Lamdage22 on September 28, 2016, at 5:27:39
In reply to Re: What's Trazodone, why I've never heard of it..... » Lamdage22, posted by SLS on September 27, 2016, at 6:49:41
> > i take 75mg in the morning. It does not make me tired anymore and i cant take more.
>
> In what ways does Seroquel at a dosage of 1000 mg/day help you that lower dosages do not?I take a cyp3a4 inhibitor. (Astaxanthin)
> Do you think that replacing the trazodone with Remeron might help with sleep and augment Effexor at the same time?
>
>
> - ScottI was pretty agressive once on Remeron. I have thought about giving it another shot, too though.
Posted by Lamdage22 on September 28, 2016, at 7:13:05
In reply to Re: What's Trazodone, why I've never heard of it....., posted by Lamdage22 on September 28, 2016, at 5:27:39
> > > i take 75mg in the morning. It does not make me tired anymore and i cant take more.
> >
> > In what ways does Seroquel at a dosage of 1000 mg/day help you that lower dosages do not?
>
> I take a cyp3a4 inhibitor. (AstaxanthinI mean inducer, sorry!
)
>
> > Do you think that replacing the trazodone with Remeron might help with sleep and augment Effexor at the same time?
> >
> >
> > - Scott
>
> I was pretty agressive once on Remeron. I have thought about giving it another shot, too though.
>
Posted by SLS on September 28, 2016, at 7:27:59
In reply to Re: What's Trazodone, why I've never heard of it....., posted by Lamdage22 on September 28, 2016, at 7:13:05
> > > > i take 75mg in the morning. It does not make me tired anymore and i cant take more.
> > >
> > > In what ways does Seroquel at a dosage of 1000 mg/day help you that lower dosages do not?
> >
> > I take a cyp3a4 inhibitor. (Astaxanthin
>
> I mean inducer, sorry!That makes more sense.
:-)
I never heard of astaxanthin. What does it do for you?
- Scott
Posted by Lamdage22 on September 28, 2016, at 10:36:30
In reply to Re: What's Trazodone, why I've never heard of it..... » Lamdage22, posted by SLS on September 28, 2016, at 7:27:59
I think it helps against inflammation
This is the end of the thread.
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