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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by kilo8 on May 25, 2015, at 16:43:33
I just started with it. I have been taking 5mg for 4 days now. No effect so far. Also no huge side effects expect that my muscles on the arm started to pulsate every now and then which is really annoying. I had the same effect when I started taking Lexapro back then. This must be coming from the drug.
Anyway I searched online for testimonies and most people who took it weren't happy with it. I do not really expect very much from it.
I also don't know how hard it is on the liver and wether it has many drug interactions. Prozac for example has many interactions because of CYP 2D6 which is a reason not to take it. I don't know how vortioxetine compares to other SSRI when it comes to liver metabolism.
Posted by SLS on May 25, 2015, at 21:10:31
In reply to Who has tried Vortioxetine?, posted by kilo8 on May 25, 2015, at 16:43:33
> I just started with it. I have been taking 5mg for 4 days now. No effect so far. Also no huge side effects expect that my muscles on the arm started to pulsate every now and then which is really annoying. I had the same effect when I started taking Lexapro back then. This must be coming from the drug.
>
> Anyway I searched online for testimonies and most people who took it weren't happy with it. I do not really expect very much from it.
>
> I also don't know how hard it is on the liver and wether it has many drug interactions. Prozac for example has many interactions because of CYP 2D6 which is a reason not to take it. I don't know how vortioxetine compares to other SSRI when it comes to liver metabolism.I hope this drug helps you. Some researchers believe that 5-HT7 receptor antagonism exerts an antidepressant effect.
Why does the ability of Prozac to inhibit 2D6 concern you? Would you avoid Wellbutrin or Paxil for the same reason?
Thanks.
- Scott
Posted by TriedEveryMedication on May 26, 2015, at 10:01:21
In reply to Who has tried Vortioxetine?, posted by kilo8 on May 25, 2015, at 16:43:33
I took it for several months. Its effects are subtle, but I thought it was a good medication.
No side-effects that I noticed. Minimal numbing/dumbing-down that comes from ADs.
Maybe one of the best ADs I've ever taken. Not quite as effective as Effexor was for me, but I think it was better than effexor overall due to the lack of sides.
Effexor was messing with my liver levels. On vortioxetine I was getting monthly blood tests. My liver levels settled down and never were a problem on this drug.
Give it some time - like I said - the effects are subtle, but good.
Posted by europerep on May 26, 2015, at 14:53:06
In reply to Re: Who has tried Vortioxetine? » kilo8, posted by TriedEveryMedication on May 26, 2015, at 10:01:21
Just out of curiosity, why did you eventually stop taking vortioxetine, and for what exact condition did you take it (if I may ask)?
Posted by phidippus on June 11, 2015, at 1:01:36
In reply to Who has tried Vortioxetine?, posted by kilo8 on May 25, 2015, at 16:43:33
I did well on Vortioxetine. I was impressed with what was a quick onset of anxiolytic effect. I felt much less anxious on it about 2 weeks into taking it.
Eric
Posted by kilo8 on June 11, 2015, at 21:47:24
In reply to Re: Who has tried Vortioxetine? » kilo8, posted by phidippus on June 11, 2015, at 1:01:36
Hello, I have been on 10mg for 14 days now before I was on 5mg for 14 days. I cannot say I feel any better at all. I am disappointed. I still feel as depressed as always and also get as restless as always. If these drugs are so damn weak that you notice no difference then they are useless. :(
Posted by phidippus on June 12, 2015, at 14:37:28
In reply to Re: Who has tried Vortioxetine?, posted by kilo8 on June 11, 2015, at 21:47:24
You may need to increase the dose to 20 mg. A couple of studies suggest that a 20 mg dose is much more effective than the 5 mg recommended.
I'd double it at this point then in another 2 weeks bump it up to 15 mg.
Eric
Posted by kilo8 on June 12, 2015, at 20:07:45
In reply to Re: Who has tried Vortioxetine? » kilo8, posted by phidippus on June 12, 2015, at 14:37:28
I have been at 10mg for 2 weeks.
I could not find studies saying that 20mg is better than 10mg. If you know any show them to me.I feel like this stuff is as useless as all other meds I tried. :(
This is the end of the thread.
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