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Dr. Bob is Robert Hsiung, MD,
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Posted by linkadge on February 5, 2015, at 20:21:51
I see severe anxiety as possibly being part of an epileptic spectrum. Why do they throw antidepressants (proconvulsant) at anxiety disorders which may be already due to epileptic like brain activity.
Antidepressants tend to make things louder for me. They tend to activate not supress.
Posted by linkadge on February 5, 2015, at 20:31:05
In reply to proconvulsant vs. anticonvulsant, posted by linkadge on February 5, 2015, at 20:21:51
Offidani and colleagues added. Hackett and colleagues2 compared diazepam and venlafaxine extended-release in 540 patients with GAD. Results showed no significant differences in response rates between groups, but discontinuations and adverse effects were more frequent in patients treated with venlafaxine. - See more at: http://www.psychiatrictimes.com/anxiety/benzodiazepines-vs-antidepressants-anxiety-disorders#sthash.lKhXhOpa.dpuf
Posted by ed_uk2010 on February 6, 2015, at 8:24:18
In reply to Re: proconvulsant vs. anticonvulsant, posted by linkadge on February 5, 2015, at 20:31:05
Overall, side effects are definitely more common with venlafaxine than say escitalopram when used for anxiety. I don't think venlafaxine is a good first choice for GAD.
Interestingly enough, I've read that some pts with epilepsy have fewer seizures when on low to standard doses of SSRIs. They don't seem proconvulsant for the majority. Some ADs such as clomipramine are clearly proconvulsant.
Posted by phidippus on February 10, 2015, at 16:31:48
In reply to proconvulsant vs. anticonvulsant, posted by linkadge on February 5, 2015, at 20:21:51
Antidepressants are routinely prescribed to treat depression amongst epileptic patients.
Some studies show the incidence of seizures is lessened by the administration of antidepressants. The theory being that ADs lessen stress.
Eric
This is the end of the thread.
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