Shown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by hello123 on October 24, 2014, at 19:37:09
"SSRI's are believed to increase the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin in the synaptic cleft available to bind to the postsynaptic receptor."
I got that quote from the SSRI article on Wikipedia. I thought this was basically the one thing that was a known fact about SSRI's?
Posted by Lamdage22 on October 25, 2014, at 10:49:17
In reply to SSRI's are *believed* to increase Serotonin?, posted by hello123 on October 24, 2014, at 19:37:09
I think it means that this reuptake inhibition is believed to be the course of action.
It is known that they inhibit serotonin reuptake but it is not known if this is what constitutes their "antidepressant effect".
Please correct me if i am out of line here.
I set that in quotes because for me there is no such thing with ssri. And i have good company!
Posted by burial on October 25, 2014, at 13:20:26
In reply to Re: SSRI's are *believed* to increase Serotonin?, posted by Lamdage22 on October 25, 2014, at 10:49:17
i think desensitization of somadentritic 5ht 1a receptors is as important, as the inhibition of reuptake, that's why you have to wait some time for antidepresants to work fully
Posted by Phillipa on October 25, 2014, at 17:29:36
In reply to Re: SSRI's are *believed* to increase Serotonin?, posted by burial on October 25, 2014, at 13:20:26
If they do. Isn't there now some controversy over whether they work or not? Just asking P
Posted by Topdog on October 29, 2014, at 14:14:56
In reply to SSRI's are *believed* to increase Serotonin?, posted by hello123 on October 24, 2014, at 19:37:09
Ordinary AD-s are for ordinary people, i need something toxic, something industrial.. I use Nardil or Ketamine.
And as always,
Good luck!
Posted by kirkglen on November 18, 2014, at 9:08:28
In reply to Re: SSRI's are *believed* to increase Serotonin?, posted by Topdog on October 29, 2014, at 14:14:56
Topdog
You're right. The SSRI's and SNRI's are for people that are sad.....not depressed. Nardil is the best drug ever created. Just assure you utilize the Gavis brand and all your bottles are sealed with the carbon desiccant inside to stop the medicine from breaking down and you have this sulfur odor when you open the bottle.
I wish everyone on this site would utilize the Gavis Nardil.
Posted by Lamdage22 on November 20, 2014, at 3:08:19
In reply to Re: SSRI's are *believed* to increase Serotonin?, posted by kirkglen on November 18, 2014, at 9:08:28
I sure would if i wasnt prone to psychosis.
This is the big drawback of Nardil and co. Its very unfortunate.
This is the end of the thread.
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