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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by Hugh on June 25, 2014, at 10:19:19
This small crossover study found that only 1 of 18 patients with treatment-resistant depression was helped by the placebo (saline nasal spray) while 8 of 18 were helped by ketamine nasal spray.
http://www.biologicalpsychiatryjournal.com/article/S0006-3223%2814%2900227-3/abstract
Nancy Sajben is a doctor in La Jolla, California who prescribes intranasal ketamine.
Posted by Phillipa on June 25, 2014, at 10:36:04
In reply to Intranasal ketamine for depression, posted by Hugh on June 25, 2014, at 10:19:19
Hugh that isn't very many is it? Phillipa
Posted by Hugh on June 25, 2014, at 12:34:38
In reply to Re: Intranasal ketamine for depression » Hugh, posted by Phillipa on June 25, 2014, at 10:36:04
> Hugh that isn't very many is it? Phillipa
Keep in mind that these were treatment-resistant patients, who hadn't been helped, or helped very much, by previous treatments. Looking at it this way, a positive response rate of 44% is promising.
Posted by Beckett on June 25, 2014, at 22:39:11
In reply to Intranasal ketamine for depression, posted by Hugh on June 25, 2014, at 10:19:19
Hugh, do you know how long a single treatment lasts? And is Namanda an nmda antagonist?
I'd like to find a progressive psychiatrist here.
Posted by Hugh on June 26, 2014, at 9:53:21
In reply to Re: Intranasal ketamine for depression » Hugh, posted by Beckett on June 25, 2014, at 22:39:11
Some people just use it occasionally, as needed, some use it daily, some use it more than once a day. Here people discuss their use of intranasal ketamine and ketamine infusions:
http://www.ketamineadvocacynetwork.org/forums/topic/my-experience-with-ketamine/
For depression and bipolar, Dr. Sajben likes to combine intranasal ketamine and oxytocin.
This article discusses ketamine and memantine (Namenda):
Posted by Willful on July 1, 2014, at 10:37:59
In reply to Intranasal ketamine for depression, posted by Hugh on June 25, 2014, at 10:19:19
It has some downsides, though, doesn't it? Memory-- or cognitive-- effects? How do those work in when people take it freqauently? I know someone who's working on it in NY, too. I think his clinical trial is looking for subjects.
Posted by Hugh on July 3, 2014, at 13:40:43
In reply to Re: Intranasal ketamine for depression, posted by Willful on July 1, 2014, at 10:37:59
> It has some downsides, though, doesn't it? Memory-- or cognitive-- effects? How do those work in when people take it freqauently?
I don't know.
> I know someone who's working on it in NY, too. I think his clinical trial is looking for subjects.
Is that Demitri Papolos?
This is the end of the thread.
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