Psycho-Babble Medication Thread 1067339

Shown: posts 1 to 7 of 7. This is the beginning of the thread.

 

Intranasal ketamine for depression

Posted by Hugh on June 25, 2014, at 10:19:19

This small crossover study found that only 1 of 18 patients with treatment-resistant depression was helped by the placebo (saline nasal spray) while 8 of 18 were helped by ketamine nasal spray.

http://www.biologicalpsychiatryjournal.com/article/S0006-3223%2814%2900227-3/abstract

Nancy Sajben is a doctor in La Jolla, California who prescribes intranasal ketamine.

http://painsandiego.com

 

Re: Intranasal ketamine for depression » Hugh

Posted by Phillipa on June 25, 2014, at 10:36:04

In reply to Intranasal ketamine for depression, posted by Hugh on June 25, 2014, at 10:19:19

Hugh that isn't very many is it? Phillipa

 

Re: Intranasal ketamine for depression

Posted by Hugh on June 25, 2014, at 12:34:38

In reply to Re: Intranasal ketamine for depression » Hugh, posted by Phillipa on June 25, 2014, at 10:36:04

> Hugh that isn't very many is it? Phillipa

Keep in mind that these were treatment-resistant patients, who hadn't been helped, or helped very much, by previous treatments. Looking at it this way, a positive response rate of 44% is promising.

 

Re: Intranasal ketamine for depression » Hugh

Posted by Beckett on June 25, 2014, at 22:39:11

In reply to Intranasal ketamine for depression, posted by Hugh on June 25, 2014, at 10:19:19

Hugh, do you know how long a single treatment lasts? And is Namanda an nmda antagonist?

I'd like to find a progressive psychiatrist here.

 

Re: Intranasal ketamine for depression » Beckett

Posted by Hugh on June 26, 2014, at 9:53:21

In reply to Re: Intranasal ketamine for depression » Hugh, posted by Beckett on June 25, 2014, at 22:39:11

Some people just use it occasionally, as needed, some use it daily, some use it more than once a day. Here people discuss their use of intranasal ketamine and ketamine infusions:

http://www.ketamineadvocacynetwork.org/forums/topic/my-experience-with-ketamine/

For depression and bipolar, Dr. Sajben likes to combine intranasal ketamine and oxytocin.

This article discusses ketamine and memantine (Namenda):

http://www.medicaldaily.com/ketamine-provides-rapid-relief-severe-depression-hallucinatory-drug-safe-288310

 

Re: Intranasal ketamine for depression

Posted by Willful on July 1, 2014, at 10:37:59

In reply to Intranasal ketamine for depression, posted by Hugh on June 25, 2014, at 10:19:19

It has some downsides, though, doesn't it? Memory-- or cognitive-- effects? How do those work in when people take it freqauently? I know someone who's working on it in NY, too. I think his clinical trial is looking for subjects.

 

Re: Intranasal ketamine for depression » Willful

Posted by Hugh on July 3, 2014, at 13:40:43

In reply to Re: Intranasal ketamine for depression, posted by Willful on July 1, 2014, at 10:37:59

> It has some downsides, though, doesn't it? Memory-- or cognitive-- effects? How do those work in when people take it freqauently?

I don't know.

> I know someone who's working on it in NY, too. I think his clinical trial is looking for subjects.

Is that Demitri Papolos?


This is the end of the thread.


Show another thread

URL of post in thread:


Psycho-Babble Medication | Extras | FAQ


[dr. bob] Dr. Bob is Robert Hsiung, MD, bob@dr-bob.org

Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.