Shown: posts 1 to 16 of 16. This is the beginning of the thread.
Posted by MeezerCat on May 26, 2014, at 8:14:25
Hello,
Upon taking Brand Wellbutrin 150XL it flooded my system for 6 Hours, as if it was all being released at once. The flooding was so intense my heart hurt- it felt like it was being pinched if you will.
What could be a logical explanation as to why it flooded me for 6 hours opposed to it slowly releasing over a 24hr period?
...Debating whether to give it another try...
I have some notions as to why this may have occurred.
IR Brand sedated me and confused me yet it was enough to get me out of bed and be productive.
Thoughts? Please share.
Thank You,
MeezerCat
Posted by phidippus on May 26, 2014, at 18:47:49
In reply to Wellbutrin XL150 Flooded Me 6 Hours/Crashed.., posted by MeezerCat on May 26, 2014, at 8:14:25
What do you mean welbutrin 150xl 'flooded' you?
Eric
Posted by MeezerCat on May 26, 2014, at 20:20:39
In reply to Re: Wellbutrin XL150 Flooded Me 6 Hours/Crashed.. » MeezerCat, posted by phidippus on May 26, 2014, at 18:47:49
It felt like the entire pill released the medication at once and flooded/overwhelmed my system.It didn't release slowly as it should have.
Have confirmed it is indeed Brand Name and the correct dose/pill and the pill was not cut nor crushed.
Posted by Phillipa on May 26, 2014, at 22:39:02
In reply to Re: Wellbutrin XL150 Flooded Me 6 Hours/Crashed.., posted by MeezerCat on May 26, 2014, at 20:20:39
Wellbutrin regular at 150mg sent me to the hospital after a week . I appeared manic to the doctor. Never again for me Phillipa
Posted by Zyprexa on May 27, 2014, at 4:55:21
In reply to Wellbutrin XL150 Flooded Me 6 Hours/Crashed.., posted by MeezerCat on May 26, 2014, at 8:14:25
I like the SR version. I tried xl and it was not pleasant, yes it did come down after 6 hours or so. I would take sr 3 times a day and never feel tired. With each meal.
Posted by MeezerCat on May 27, 2014, at 7:18:00
In reply to Re: Wellbutrin XL150 Flooded Me 6 Hours/Crashed.., posted by Zyprexa on May 27, 2014, at 4:55:21
Hello,
Any thoughts as to why the XL lasted only 6 hours opposed to the expected 24 hours?
It did indeed flood/overwhelm my system. As I experienced the symptoms described in previous posts.
Perhaps another try should be attempted..?
Thoughts?
Thank You,
Meezers
Posted by phidippus on May 27, 2014, at 14:40:33
In reply to Re: Wellbutrin XL150 Flooded Me 6 Hours/Crashed.., posted by MeezerCat on May 26, 2014, at 20:20:39
> It felt like the entire pill released the medication at once and flooded/overwhelmed my system.
I'm sure this was not the case. Plus its a relatively small dose-150 mg would not have that strong an effect.
Eric
Posted by MeezerCat on May 28, 2014, at 15:46:50
In reply to Re: Wellbutrin XL150 Flooded Me 6 Hours/Crashed.. » MeezerCat, posted by phidippus on May 27, 2014, at 14:40:33
> > It felt like the entire pill released the medication at once and flooded/overwhelmed my system.
>
> I'm sure this was not the case. Plus its a relatively small dose-150 mg would not have that strong an effect.
>
> EricOh..I wasn't aware that you were a psychiatrist, neurosurgeon, And a neurochemist phi dipp us. You must be very busy, how do you find time to post all day..?
And having the ability to sympathetically share your oh so in depth and insightful neurochemical knowledge of My Own Unique Brain Makeup is outstanding. Simply outstanding.
You must be very wealthy from your vast knowledge. Everyone should listen to you as you clearly understand what you're talking about.I particularly enjoyed your intellectually stimulating statement and thorough comprehension of my own unique brain chemistry:
"I'm sure this was not the case."
I better not listen to the top psychiatrists.
It's evident everyone on this board should undoubtedly listen to you as you clearly know what you're talking about. As evident by your strongly supported and highly intellectual statements.Perhaps the publication of a book is in order. A grand way to earn money off the plights and distress of others. I'm certain Robert (Bob) Hsiung could offer you some hearty tips in that department.
So according to you phi dipp us apparently everyone's brain chemistry is the same... So all our medication problems are solved everyone! Hip Hip Hooray for phi dipp us.
**So Listen up Wellbutrin users:: If indeed you do try the 150XL let it be noted that there's no way it will overstimulate your brain. This is evident and can indeed be confirmed by phi dipp us's statement:
"its a relatively small dose-150 mg would not have that strong an effect".
So despite side effects of overstimulation listed on the XL website... and despite past posts within this website stating that 150XL was overstimulating it's just not true accoring to phi dipp us.
Even those of you stated that 75IR made you nervous, anxious, angry, and overstimulated it just isn't so..because phi dipp us says so.
>Wow I'm so fortunate to have posted my plight with Wellbutrin here. I feel so much more educated than prior to coming here.
Bravo..... Bravo..... phi dipp us
Thank You for your enlightenment, as well a hearty chuckle today.
MeezerCat
Posted by phidippus on May 28, 2014, at 16:57:52
In reply to RE:WLLB XL150/ ERIC HAS SOLVED ALL OUR PROBLEMS, posted by MeezerCat on May 28, 2014, at 15:46:50
I see you were unable to replicate your initial response.
Eric
Posted by MeezerCat on May 28, 2014, at 17:22:07
In reply to RE:WLLB XL150/ ERIC HAS SOLVED ALL OUR PROBLEMS » MeezerCat, posted by phidippus on May 28, 2014, at 16:57:52
> I see you were unable to replicate your initial response.
>
> Eric
I had no intention of doing so. Is there a rule that must be done..?
Posted by phidippus on May 28, 2014, at 17:47:48
In reply to RE:WLLB XL150/ ERIC HAS SOLVED ALL OUR PROBLEMS, posted by MeezerCat on May 28, 2014, at 17:22:07
If you experience an unusual response to a medication, it is always best to take it again to see if your response is the same. This will rule out psychological factors.
Eric
Posted by MeezerCat on May 28, 2014, at 21:33:05
In reply to RE:WLLB XL150/ ERIC HAS SOLVED ALL OUR PROBLEMS » MeezerCat, posted by phidippus on May 28, 2014, at 17:47:48
> If you experience an unusual response to a medication, it is always best to take it again to see if your response is the same. This will rule out psychological factors.
>
> EricPerhaps you were grasping for the term psychosocialpharmacology - break it down and think about it-.... psychosocialpharmacology simply recognizes Psychological, Behavioral, and Social Factors. All these factors combined, can undoubtedly influence how one unique individual's chemistry is affected by medication. An individuals view, or opinion, if you will, rergarding medication can be taken into account as well.. Psychosocialpharmocology takes into consideration how an individual metabolizes medication, breaks it down, and how Quickly Or How Slowly one's absorption rate is, the overall efficiancy, and side effects one expereinces as well.
Genes which can be taken into consideration as well. Genes inevitably affect the way medications work as well... Our genes instruct our body how to make enzymes..in turn enzymes are of great signifigance as they break down medications to bring about a specific biochemical reaction. Simply said breaking down the medications allows our body to feel the affects.. Genes are also of signifigance as each of us carries Two copies of each gene.. those of being of one from your mother and one from your father.
Speeding this up here the differences held within these genes inevitably affect the rate of which various enzymes within your body work.
In turn this affects just how well an individuals body can break down and metabolize a medication. AS WEll as how long a particular medication stays within your body as a whole. Of course these factors are of significance as they ultimately determine just how well medications will work within our body.
To sum it up based on what type of genes you carry simply defines what type of a drug metabolizer you just may be.
So variance in ones individual enzymes can determine just how long a medication will break itself down, how powerful it may be, and and how long it will remain within our body.
So as evident from previous medications trial and error I am indeed considered a poor drug metabolizer..meaning I simply do not metabolize medications well. Thus, the unfortunate result being that of "a flooding feeling or overwhelming of my system" as a result of certain medications.As I initially stated with the XL.
This can be quite frightening as well as dangerous for me as my system is essentially being overloaded with medication. It's quite distressing to even consider the notion death may inevitably occur as a result of "flooding."
It can also be quite frustrating as medication may not even be able to metabolize and even reach the point of being an effective working formulation for me. Thus the end result being failure of a medication even having a remote chance of working appropriately.
Lastly this notion can indeed be confirmed by extensive genetic tests for ones individual drug responses.
Perhaps rather than taking a Simplistic view such as a basic psychological view take a more intellectual esoteric view.
...Now Perhaps I'll Write A Book....
Thank You,
Meezers
Posted by Phillipa on May 28, 2014, at 22:11:39
In reply to RE:WLLB XL150/ ERIC HAS SOLVED ALL OUR PROBLEMS, posted by MeezerCat on May 28, 2014, at 21:33:05
Louisiana Sportsman? This sounds a bit like you? Phillipa
Posted by phidippus on May 29, 2014, at 20:00:50
In reply to RE:WLLB XL150/ ERIC HAS SOLVED ALL OUR PROBLEMS, posted by MeezerCat on May 28, 2014, at 21:33:05
>Perhaps you were grasping for the term psychosocialpharmacology
Psychological was the term I was grasping for.
Poignant biological lesson aside, you simply missed my point. When you take a medication, the action is accompanied by a psychological reaction that may be built on false assumptions. A popular reaction I witness is when a person starts taking an antidepressant and immediately claims relief. It takes most antidepressants weeks to take effect. Not taking into account your freakish metabolism, your reaction to that first dose of Wellbutrin XL could have been purely psychological-it could've been an anxiety response. That's why I urged you to take it a second time, which I think you did and did not experience the same 'flooding' sensation.
I've learned to never trust my first reaction to a drug-there may be psychological factors at play. I remember trying carbamazapine for the first time. I was sure it caused me to be depressed the first day I took it, so I swore it off. Sometime later I tried it again and stayed on it for a week without any mood disturbances. I must have been depressed the first time I took it, not depressed because of it.
Eric
Posted by Chris O on June 2, 2014, at 3:16:35
In reply to Wellbutrin XL150 Flooded Me 6 Hours/Crashed.., posted by MeezerCat on May 26, 2014, at 8:14:25
Hard to know what happened. These drugs affect all of us so differently and throwing the generic vs. brand name differences into the mix is another annoyance, in my opinion.
I just took Wellbutrin XL (300mg a day) for three weeks and it did very little for me. It did seem to work immediately, but made me a bit more anxious and unfocused, if anything. I took it with 30mg of Brintillex a day. I thought it would activate me in a positive way, but just made it harder to concentrate. I hope you find something that works for you.
Chris
Posted by Zyprexa on June 3, 2014, at 2:11:41
In reply to Re: Wellbutrin XL150 Flooded Me 6 Hours/Crashed.., posted by MeezerCat on May 27, 2014, at 7:18:00
Try a more short action wellbutrin, like sr or even ir, several times a day. I found that xl may have lasted longer than sr, butthe effect was deffinitly not 24 hours. Also I found that xl had a very different effect than sr, I didn't like xl at all.
This is the end of the thread.
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