Psycho-Babble Medication Thread 1065933

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saphris or risperdal for depression?

Posted by mogger on May 21, 2014, at 21:24:50

Going in to see my pdoc tomorrow to discuss coming off zyprexa as it is doing nothing for my depression/ocd but mostly depression. Latuda was great for depression but the akathisia was unbearable even at 20 mgs. Any experiences with saphris or risperdal? Thank you,

Mogger

 

Re: saphris or risperdal for depression?

Posted by Beckett on May 21, 2014, at 22:10:33

In reply to saphris or risperdal for depression?, posted by mogger on May 21, 2014, at 21:24:50

Hi Mogger,

I have used low dose risperdal, which didn't help with depression, but helped somewhat with mood stability.

Saphris helped my depression so much that I became hypomanic. But it was one of the nicest episodes I've experienced :) It's amazing for sleep and more tolerable (to me) than Seroquel. It kinda' was an addictive drug in that I craved it. Weird.

I must warn you that when I came off, I became anhedonic,, but that can happen after AP use. I probably should have taken half or a quarter of the wafer.

Do you deal with bipolar?

 

Re: saphris or risperdal for depression?

Posted by tom2228 on May 21, 2014, at 22:10:51

In reply to saphris or risperdal for depression?, posted by mogger on May 21, 2014, at 21:24:50

What about Latuda with Mirapex (ER) to offset the akathisia (Mirapex is indicated for restless leg syndrome)? I take Mirapex myself with Abilify, I got on it when I was on Latuda and noticed a difference in my akathisia feelings.

I don't have enough experience to say about Risperdal but it can be good as a depression augment.

I would recommend Saphris -- it had a really nice AD effect for me at 5mg (that lessened for me at 10mg) that started really quickly -- within 2 days. My counselor has heard of it being used for *unipolar* depression at her last job.

 

Re: saphris or risperdal for depression? » tom2228

Posted by mogger on May 21, 2014, at 22:53:12

In reply to Re: saphris or risperdal for depression?, posted by tom2228 on May 21, 2014, at 22:10:51

I am unipolar. Thank you both for your responses. I shall opt with saphris as I think it is worth a shot at this point. Hopefully the saphris along with my other ADs will help. My fingers are crossed. Thanks again,

Mogger

 

Re: saphris or risperdal for depression? » mogger

Posted by phidippus on May 22, 2014, at 14:12:47

In reply to saphris or risperdal for depression?, posted by mogger on May 21, 2014, at 21:24:50

Saphris has more 5ht1a agonism (Risperdal actually antagonizes 5ht1a). This helps with depressive symptoms.

Try Geodon. It agonizes 5ht1a and 5ht1b receptors and is also a SNRI.

Eric

 

Re: saphris or risperdal for depression? » phidippus

Posted by mogger on May 22, 2014, at 14:46:33

In reply to Re: saphris or risperdal for depression? » mogger, posted by phidippus on May 22, 2014, at 14:12:47

My doctor isn't a fan of Geodon in his experience. Are you on it?

 

Re: saphris or risperdal for depression? » mogger

Posted by phidippus on May 22, 2014, at 14:47:24

In reply to Re: saphris or risperdal for depression? » phidippus, posted by mogger on May 22, 2014, at 14:46:33

I'm on it and it has been killer for my mood.

Eric

 

Re: saphris or risperdal for depression? » phidippus

Posted by mogger on May 22, 2014, at 14:48:29

In reply to Re: saphris or risperdal for depression? » mogger, posted by phidippus on May 22, 2014, at 14:47:24

Good to hear.


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