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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by Sheilac on December 4, 2013, at 18:08:49
I've been taking 120mg of Geodon and I notice that while it works for stabilization, I've lost the antidepressant effect. Is this possible?
I rely on Geodon for the great AD effect.
What the heck? Too high a dose for AD effect?
Posted by SLS on December 4, 2013, at 19:52:09
In reply to Geodon: lost AD effect..., posted by Sheilac on December 4, 2013, at 18:08:49
> I've been taking 120mg of Geodon and I notice that while it works for stabilization, I've lost the antidepressant effect. Is this possible?
>
> I rely on Geodon for the great AD effect.
>
> What the heck? Too high a dose for AD effect?The reappearance of your depression could be a temporary medication breakthrough that is sometimes the consequence of an increase in psychosocial stress. It can also represent a spontaneous biological shift in the function of the brain. Such shifts can also be temporary.
Too high a dosage of Geodon? I'm not sure. The only psychotropic drug that I am aware of that has such a window of efficacy is nortriptyline. That having been said, I have seen rapid changes in antidepressant dosages (up or down) lead to temporary improvements that ultimately disappear. Sometimes, a drug will have a narrow therapeutic index, which means that the drug will produce undesirable side effects at a dosage that is not very much higher than that which produces the desired therapeutic effect. Lithium acts this way.
How long ago did Geodon completely "poop-out" on you?
I notice that you self-medicate and change your drug regime quite often. Do you think you have a problem with impulsiveness? I have fallen into that trap myself. Stability of mood depends on consistency of medical treatment, biological homeostasis, and the passage of time.
Latuda (lurasidone) is a neuroleptic antipsychotic that can act as an energizing antidepressant. Perhaps you can mention it to your doctor. Saphris (asenapine) also has some interesting antidepressant properties.
- Scott
Posted by Jeroen on December 5, 2013, at 5:28:38
In reply to Geodon: lost AD effect..., posted by Sheilac on December 4, 2013, at 18:08:49
i had the same problem with seroquel i relied on its AD effects, but after 2 months it stopped working
i'm sorry but your mem might have pooped out : (
Posted by Sheilac on December 5, 2013, at 6:28:53
In reply to Re: Geodon: lost AD effect... » Sheilac, posted by SLS on December 4, 2013, at 19:52:09
Scott, it was my doc's thinking that since I was experiencing swelling with Trileptal, we would try upping the Geodon, but I miss Trileptal.
It's weird because I don't eat salt. But I do have swelling from Raynaud's Disease in my feet.
I always got great AD results from lower dose Geodon. I'm seeing her soon and going to discuss adding back a lower dose of Trileptal (since I miss it so bad - it keeps me from getting too depressed) and lowering the Geodon so I can get more AD effect.
Maybe if I go slowly up on Trileptal, instead of 0-1200mg, I won't aggravate the swelling.
Also, I didn't know that I should supplement with folic acid and other supplements while on Trileptal? Maybe I should try that.
I just love Trileptal. The irritability is terrible without it and I can't take ADs.
It's all very frustrating.
Posted by SLS on December 5, 2013, at 7:09:14
In reply to Re: Geodon: lost AD effect... » SLS, posted by Sheilac on December 5, 2013, at 6:28:53
> Scott, it was my doc's thinking that since I was experiencing swelling with Trileptal, we would try upping the Geodon, but I miss Trileptal.
> It's weird because I don't eat salt. But I do have swelling from Raynaud's Disease in my feet.Hyponatremia is a side effect of Trileptal. It produces edema.
Can you describe in more detail how Geodon made you feel when it worked? When it stopped working, did you feel as bad as before you started taking it? I am very interested to read your posts when you reduce the dosage of Geodon. According to Stephen Stahl, MD, it is possible that the lower dosage will leave you more agitated. You may not have this happen to you, though. It might be worth exploring the use of Latuda (lurasidone) as a substitute for Geodon. I am trying to get a better feel for this drug, but not too many people on Psycho-Babble have tried it yet. However, one of my "scouts" found some positive anecdotes on other Internet forums.
- Scott
Posted by Sheilac on December 5, 2013, at 8:31:59
In reply to Re: Geodon: lost AD effect... » Sheilac, posted by SLS on December 5, 2013, at 7:09:14
How to you stop hyponatremia? I love Trileptal and think my brain is missing it, but don't want the added edema.
20mg of Geodon makes me irritable. 40mg of Geodon makes me hypomanic. 60-80mg helps with depression. 100-120mg Geodon makes me feel flat and depressed.
Trileptal is like a safety net that keeps me from getting too down, I just need to figure out how to avoid the dreaded edema. Lower the Trileptal dose? Take some sort of supplement? drink more water? I don't know. I just know I'm now depressed without Trileptal.
Posted by Phillipa on December 5, 2013, at 9:57:49
In reply to Re: Geodon: lost AD effect... » SLS, posted by Sheilac on December 5, 2013, at 8:31:59
Sheila I didn't know you have Renauds. Do you take meds for this also? Phillipa
Posted by sheilac on December 5, 2013, at 12:57:53
In reply to Re: Geodon: lost AD effect... » Sheilac, posted by Phillipa on December 5, 2013, at 9:57:49
No. I guess sometimes if it gets painful I will take Aleve. The swelling & joint pain hurts.
Posted by baseball55 on December 5, 2013, at 19:37:03
In reply to Re: Geodon: lost AD effect... » Phillipa, posted by sheilac on December 5, 2013, at 12:57:53
I'm confused. I don't remember that much about A&P, but I thought edema was caused by too much salt, not too little. Salt causes water retention, right?
Posted by Phillipa on December 5, 2013, at 21:09:00
In reply to Re: Geodon: lost AD effect..., posted by baseball55 on December 5, 2013, at 19:37:03
Yes it does and water flushes it out. Phillipa
This is the end of the thread.
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