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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 29 to 53 of 53. Go back in thread:
Posted by SLS on September 17, 2013, at 22:17:58
In reply to Re: Thoughts on AAPs -Scott, posted by Sheilac on September 17, 2013, at 19:20:38
> Scott, Trileptal & Depakote depressed me.
I would then consider Topamax or Keppra. I have seen Topamax effectively and completely treat BPII mixed states at a dosage of 100 mg/day. With Topamax, it is important to start low and titrate slowly. If you do this, it will help you to avoid cognitive impairments.
Which AAPs work best for you?
- Scott
Posted by 10derheart on September 17, 2013, at 22:24:30
In reply to Lou's reply-debbi » Phil, posted by Lou Pilder on September 17, 2013, at 16:22:15
>> P,
YOu wrote,[...a {hideous} song...]
I am unsure as to what you are wanting to mean here.Phil means that he doesn't like the song?
A love song, per songwriter.
Ms. Boone (not original artist) always said she thinking about/singing to God when she performed it.
Posted by Phil on September 18, 2013, at 14:21:54
In reply to Re: Lou's reply-debbi » Lou Pilder, posted by 10derheart on September 17, 2013, at 22:24:30
The song was/is awful and every station had it on heavy rotation. I put that song in the same category as Muskrat Love, Feelings, and Afternoon Delight. Actually Afternoon Delight beats the others.
We used to get requests to play Feelings and the singer would say, sorry never heard of it. Have you noticed that we're a rock band and not a schlock band? :))
Posted by Lou Pilder on September 18, 2013, at 19:39:11
In reply to Re: Lou's reply-debbi » 10derheart, posted by Phil on September 18, 2013, at 14:21:54
> The song was/is awful and every station had it on heavy rotation. I put that song in the same category as Muskrat Love, Feelings, and Afternoon Delight. Actually Afternoon Delight beats the others.
> We used to get requests to play Feelings and the singer would say, sorry never heard of it. Have you noticed that we're a rock band and not a schlock band? :))Phil,
Then how does this song rate? Let's welcome the Bangles
Lou
http://www.youtube.com/watch?v=ABhOKkwrOLk
Posted by Phil on September 18, 2013, at 21:21:25
In reply to Lou's response-eturnul » Phil, posted by Lou Pilder on September 18, 2013, at 19:39:11
Lou, If there's anything bad there, it's made up for by Susanna Hoffs singing it. I like the band on video. :)
Posted by Lou Pilder on September 19, 2013, at 14:09:44
In reply to Re: Lou's response-eturnul » Lou Pilder, posted by Phil on September 18, 2013, at 21:21:25
> Lou, If there's anything bad there, it's made up for by Susanna Hoffs singing it. I like the band on video. :)
Phil,
HOw does this one rate?
Lou
Let's welcome Linda Ronstadt
http://www.youtube.com/watch?v=RMuDRBxod1M
Posted by Lou Pilder on September 19, 2013, at 14:13:04
In reply to Lou's reply-ag+au, posted by Lou Pilder on September 19, 2013, at 14:09:44
> > Lou, If there's anything bad there, it's made up for by Susanna Hoffs singing it. I like the band on video. :)
>
> Phil,
> HOw does this one rate?
> Lou
> Let's welcome Linda Ronstadt
> http://www.youtube.com/watch?v=RMuDRBxod1Mcorrection:
Lou
http://www.youtube.com/watch?v=RMuDRBxodlM
Posted by Phil on September 19, 2013, at 22:34:25
In reply to Lou's reply-ag+au, posted by Lou Pilder on September 19, 2013, at 14:09:44
Good call Lou. Have you ever heard her sing in Spanish? Amazing woman.
I just saw an interview lately and I think she has MS. She may be having money problems even though she sold so many albums. As she said, the songwriters make the money.
I like your musical side Lou.
Posted by Lou Pilder on September 20, 2013, at 11:15:50
In reply to Re: Lou's reply-ag+au » Lou Pilder, posted by Phil on September 19, 2013, at 22:34:25
> Good call Lou. Have you ever heard her sing in Spanish? Amazing woman.
> I just saw an interview lately and I think she has MS. She may be having money problems even though she sold so many albums. As she said, the songwriters make the money.
> I like your musical side Lou.
>
Phil,
Linda Ronstadt was amazing. Her roots in music go back to the one that started the music to be what we hear today, and Linda took from him her start.
Here is her start to bring out what was the beginning of what we hear today, that came from him.
Lou
http://www.youtube.com/watch?v=oaignDGbdS0
and then, him that was in the beginning.
http://www.youtube.om/watch?v=XEbhyGJt80c
Posted by Lou Pilder on September 20, 2013, at 11:22:22
In reply to Lou's reply-HW, posted by Lou Pilder on September 20, 2013, at 11:15:50
> > Good call Lou. Have you ever heard her sing in Spanish? Amazing woman.
> > I just saw an interview lately and I think she has MS. She may be having money problems even though she sold so many albums. As she said, the songwriters make the money.
> > I like your musical side Lou.
> >
> Phil,
> Linda Ronstadt was amazing. Her roots in music go back to the one that started the music to be what we hear today, and Linda took from him her start.
> Here is her start to bring out what was the beginning of what we hear today, that came from him.
> Lou
> http://www.youtube.com/watch?v=oaignDGbdS0
> and then, him that was in the beginning.
> http://www.youtube.om/watch?v=XEbhyGJt80ccorrection to him:
http://www.youtube.com/watch?v=SKLI6aSmoI
Posted by Lou Pilder on September 20, 2013, at 11:27:51
In reply to correction:- Lou's reply-HW, posted by Lou Pilder on September 20, 2013, at 11:22:22
> > > Good call Lou. Have you ever heard her sing in Spanish? Amazing woman.
> > > I just saw an interview lately and I think she has MS. She may be having money problems even though she sold so many albums. As she said, the songwriters make the money.
> > > I like your musical side Lou.
> > >
> > Phil,
> > Linda Ronstadt was amazing. Her roots in music go back to the one that started the music to be what we hear today, and Linda took from him her start.
> > Here is her start to bring out what was the beginning of what we hear today, that came from him.
> > Lou
> > http://www.youtube.com/watch?v=oaignDGbdS0
> > and then, him that was in the beginning.
> > http://www.youtube.om/watch?v=XEbhyGJt80c
>
> correction to him:
> http://www.youtube.com/watch?v=SKLI6aSmoIcorrection to correction to him:
http://www.youtube.com/watch?v=cBTTHLQS8UM
Posted by Lou Pilder on September 20, 2013, at 20:00:05
In reply to correction to correction:- Lou's reply-HW, posted by Lou Pilder on September 20, 2013, at 11:27:51
> > > > Good call Lou. Have you ever heard her sing in Spanish? Amazing woman.
> > > > I just saw an interview lately and I think she has MS. She may be having money problems even though she sold so many albums. As she said, the songwriters make the money.
> > > > I like your musical side Lou.
> > > >
> > > Phil,
> > > Linda Ronstadt was amazing. Her roots in music go back to the one that started the music to be what we hear today, and Linda took from him her start.
> > > Here is her start to bring out what was the beginning of what we hear today, that came from him.
> > > Lou
> > > http://www.youtube.com/watch?v=oaignDGbdS0
> > > and then, him that was in the beginning.
> > > http://www.youtube.om/watch?v=XEbhyGJt80c
> >
> > correction to him:
> > http://www.youtube.com/watch?v=SKLI6aSmoI
>
> correction to correction to him:
> http://www.youtube.com/watch?v=cBTTHLQS8UMPhil,
Lou
http://www.youtube.com/watch?v=jiB0e-ufkPE
then,
http://www.youtube.com/watch?v=zMb_7HDWjZo
Posted by phidippus on September 23, 2013, at 12:33:54
In reply to Thoughts on AAPs please..., posted by Sheilac on September 16, 2013, at 6:18:12
Using AAPs long term stunts brain growth. I don't think you have to be schizophrenic to warrant taking these drugs. They can be useful in controlling dopamine issues in many disorders, such as OCD.
Eric
Posted by SLS on September 24, 2013, at 5:18:41
In reply to Re: Thoughts on AAPs please... » Sheilac, posted by phidippus on September 23, 2013, at 12:33:54
> Using AAPs long term stunts brain growth.
I didn't know that. Is there some brain structures in particular that are affected? Is this more of a concern with younger people - perhaps during pruning?
- Scott
Posted by phidippus on September 24, 2013, at 12:33:23
In reply to Re: Thoughts on AAPs please... » phidippus, posted by SLS on September 24, 2013, at 5:18:41
Here's a good read: http://www.psychologytoday.com/blog/mad-in-america/201012/do-psychiatric-medications-impair-normal-brain-development
Eric
Posted by b2chica on September 24, 2013, at 14:53:59
In reply to Re: Thoughts on AAPs please... » SLS, posted by phidippus on September 24, 2013, at 12:33:23
i remember reading articles on zyprexa increasing white matter.
i think they studies persons with schizophrenia, though so not sure if can apply. persons WM increased with volume after starting olanzapine.
Posted by SLS on September 24, 2013, at 14:55:03
In reply to Re: Thoughts on AAPs please... » SLS, posted by phidippus on September 24, 2013, at 12:33:23
> Here's a good read: http://www.psychologytoday.com/blog/mad-in-america/201012/do-psychiatric-medications-impair-normal-brain-development
>
> EricHi Eric.
I have not developed a great degree of trust in this author's portrayals of psychobiology. That is not to say that AAPs do not change the trajectory of CNS development. It is hard to imagine that they wouldn't. However, this is nothing but conjecture on my part.
- Scott
Posted by phidippus on September 24, 2013, at 15:38:27
In reply to Re: Thoughts on AAPs please... » phidippus, posted by SLS on September 24, 2013, at 14:55:03
There is more research, however I can't seem to dig any up.
Eric
Posted by doxogenic boy on September 25, 2013, at 15:37:44
In reply to Re: Thoughts on AAPs please... » phidippus, posted by SLS on September 24, 2013, at 14:55:03
Here is an article from Archives of General Psychiatry that shows that antipsychotics decrease brain voume. It is the same with atypical and typical antipsychotics:http://www.power2u.org/downloads/yoa05077_128_137.pdf
Excerpt from article:
Viewed together with data from animal studies, our study suggests that antipsychotics have a
subtle but measurable influence on brain tissue loss over time, suggesting the importance of careful risk-benefit review of dosage and duration of treatment as well as their off-label use.
Arch Gen Psychiatry. 2011;68(2):128-137http://altmentalities.files.wordpress.com/2011/02/cause-for-concern.pdf
Excerpt from article:
Arch Gen Psychiatry. 2011;68(2):126-127. doi:10.1001/archgenpsychiatry.2010.187Since the initiation of antipsychotic drug therapy for schizophrenia,clinical
observations and empirical studies have demonstrated that these medications bring benefit and harm. Consequently, efforts to develop new antipsychotic medications during the past 50 years have been motivated, at least partly, by the desire to enhance the benefit to harm ratio
relative to existing medications.In this issue of the Archives, Ho and colleagues 1 examine one arm of this ratio by asking whether antipsychotic medications contribute to progressive brain volume reductions in schizophrenia. Individuals early in the course of schizophrenia (n = 211) were treated with antipsychotic medications according to standard
clinical practice and followed up longitudinally with clinical assessments and serial magnetic resonance imaging (MRI)scans (between 2 and 5 scans per individual) for a mean of 7 years.
The authors found that the amount of exposure to antipsychotic medication predicted decrements
in cerebral gray and white matter volumes and increased the volume of the putamen. Illness duration and severity were also associated with smaller brain volume measures, but the relationship between antipsychotic medication
use and brain volume remained significant after accounting for the effects of illness severity and
duration and substance abuse history. Interestingly, changes in brain volume with
time were similar for all classes of antipsychotic medications (ie, typical
antipsychotics, atypical [ie, excluding clozapine] antipsychotics,and clozapine).
End quote- doxogenic
Posted by SLS on September 25, 2013, at 19:16:45
In reply to Antipsychotics and Brain Volume » SLS, posted by doxogenic boy on September 25, 2013, at 15:37:44
Posted by Sheilac on October 3, 2013, at 15:03:20
In reply to Antipsychotics and Brain Volume » SLS, posted by doxogenic boy on September 25, 2013, at 15:37:44
Well, this doesn't make me feel any better about taking Geodon!
Posted by doxogenic boy on October 4, 2013, at 6:23:30
In reply to Re: Antipsychotics and Brain Volume, posted by Sheilac on October 3, 2013, at 15:03:20
> Well, this doesn't make me feel any better about taking Geodon!
I take my Seroquel even though I know that it can decrease my brain volume, because it works. I don't know of a better alternative for me.
- doxogenic
Posted by Babbler20 on October 15, 2013, at 23:28:22
In reply to Re: Antipsychotics and Brain Volume » Sheilac, posted by doxogenic boy on October 4, 2013, at 6:23:30
I can't imagine that taking a pill could decrease the size of your brain. Is there proof of this? I don't mean to second-guess you, this just seems sort of implausible.
Posted by SLS on October 16, 2013, at 5:05:33
In reply to Re: Antipsychotics and Brain Volume, posted by Babbler20 on October 15, 2013, at 23:28:22
> I can't imagine that taking a pill could decrease the size of your brain. Is there proof of this? I don't mean to second-guess you, this just seems sort of implausible.
I have not researched this subject very much, but it does seem that antipsychotics can reduce brain volume to some relatively small and variable degree according to quite a few studies. One confounding factor in studies is that many people with untreated schizophrenia have reduced volume of brain tissue and enlarged brain ventricles.
For now, I am not concerned with these findings, and continue to take an antipsychotic (Abilify). I have not seen any literature associating AP-induced tissue shrinkage to alterations in mental function.
- Scott
Posted by doxogenic boy on October 18, 2013, at 7:29:09
In reply to Re: Antipsychotics and Brain Volume, posted by Babbler20 on October 15, 2013, at 23:28:22
> I can't imagine that taking a pill could decrease the size of your brain. Is there proof of this? I don't mean to second-guess you, this just seems sort of implausible.
There is research saying that antipsychotics decrease brain volume. I am no expert, but I rely on this research.
http://www.power2u.org/downloads/yoa05077_128_137.pdfhttp://altmentalities.files.wordpress.com/2011/02/cause-for-concern.pdf
I still take my 600 mg Seroquel, because, in my opinion, anxiety and depression is worse than decreases of my brain. And Seroquel works for me.
- doxogenic
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