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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 16 of 16. This is the beginning of the thread.
Posted by rjlockhart37 on May 7, 2013, at 22:15:36
I've noticed as many times as I've taken zzyprexa and other sedating antipsychotics....they make me really passive, like im not bothered by things that would usally make me go crazy....its like a sedation, but its not like a xanax sedation, the thoughts are slowed down....and certain behaviors that are done disappear when zyprexa is taken. Yet like I've been saying, my meds are resistant, and sometimes when I take the zyprexa....its like nothing....god, i'm so wrecked with my body doing this....meds that I take they don't work.
also I've noticed delusions and high self esteem are lowered on zyprexa, I don't feel good about myself....im just mellow, don't feel egotistical...and then when I don't take it I get really proud of who I am....I can think faster, but I get really agitated and irrtible....
but anyways....besides that....has anyone noticed this passive feeling while taking AP's?
Posted by Zyprexa on May 7, 2013, at 22:33:15
In reply to antipsychotic passiveness, posted by rjlockhart37 on May 7, 2013, at 22:15:36
Yes, and its a good thing! I think that is how anxiety and panic are lowered tremendously. When I was on abilify panic and axiety were out of control. But remeron did not help this, which is strange. Guess it has to be an AP?
Posted by Tomatheus on May 7, 2013, at 23:43:31
In reply to antipsychotic passiveness, posted by rjlockhart37 on May 7, 2013, at 22:15:36
Yeah, RJ, I've noticed the passivity that you mentioned while taking antipsychotics, including the Abilify that I currently take to a certain extent (but to a lesser extent than with most antipsychotics). Considering that an extreme slowness of thought is what I consider to be one of my worst symptoms when untreated, I don't at all like the fact that antipsychotics seem to induce passivity and slowed thinking in those who take them. Every antipsychotic that I've taken for longer than a day or two, with the exception of Abilify at my current dose of 5 mg, seemed to significantly worsen my fatigue and hypersomnia, and for me, one of the most frustrating aspects of having schizoaffective disorder is that most of the treatments for the disorder worsen my fatigue and hypersomnia. I'm thankful that there is an antipsychotic (Abilify at 5 mg) that at least brings most of my "positive" psychotic symptoms under control without making my hypersomnia and fatigue much worse. I honestly think that if Abilify weren't available in such a strength that I probably wouldn't be taking an antipsychotic right now, unless I were forced to take one.
It's my impression based on the anecdotal reports that I've read that at least most people who take antipsychotics feel at least a bit more passive on them, whether they consider the effective to be positive, negative, or some combination of the two. What I'd be interested in knowing is if there's anybody out there who *doesn't* feel more passive on antipsychotics, especially the more sedating ones.
T.
Posted by SLS on May 7, 2013, at 23:55:35
In reply to Re: antipsychotic passiveness, posted by Tomatheus on May 7, 2013, at 23:43:31
I can't tell if Abiify is making me feel more passive, as amotivation is a feature of my baseline depression.
I have seen Saphris be energizing. I'll try to remember to ask my friend if she experiences passivity despite this increase in energy. She seems more motivated to do things, but I don't know what is her subjective experience.
- Scott
Posted by vbs on May 8, 2013, at 10:42:50
In reply to antipsychotic passiveness, posted by rjlockhart37 on May 7, 2013, at 22:15:36
Hi RJ, I feel mellow on my medication regimen. I currently take three APs: Saphris, Zyprexa, & Invega Sustenna injection. Also, I take Cymbalta & trazodone.
Posted by rjlockhart37 on May 9, 2013, at 23:41:48
In reply to Re: antipsychotic passiveness, posted by Zyprexa on May 7, 2013, at 22:33:15
yea....zyprexa is unique in itself.....the old APs where sedating but they caused more mental impairment, not all of them, but someone whos on the max dose of thorazine is usally zonked...zyprexa is a bit different, but its only with me....it sedates, but improves my mood and makes me more passive to things that would really irritate or make me get in a bad mood, and want to drink alcohol after it. Zyprexa I have to say is good for an offlabel treatment for alcoholism, it sedates the nervious system....yea...but not like benzos....
paxil is sedating...you may check into paxil but the only thing it has lots of side effects, remeron I've read so many posts here on babble about it over the years....it appears to be good for sleep, and other anxiety issues.
Abilify......yes my friend, that is exactly what it did to me, I took 15mg of abilify and this irrtible derealization, I got angry and felt unstable more......a lot of people say abilify is activating, well it is for me, but is not in a good way lol.
r
Posted by rjlockhart37 on May 9, 2013, at 23:49:40
In reply to Re: antipsychotic passiveness, posted by Tomatheus on May 7, 2013, at 23:43:31
yea....I've read and seen those abilify ads on tv, that cartoon of that lady smiling all the time with the umbrella right by her which is suppost to be her depression, its WIERD....lol
but yea...abilify, I've read is good for mood, its not really like the other APs, it works more for other conditions like depression, and mood stabilization. I can't take it, god abilify made me so angry because I couldn't think correctly, and it activated me but more in a irritable way.
Older and stuff like Zyprexa and Clozapine block the D2 receptors, causing less intrest in things, which results in being passive, it depends....but the anxiety and the mental chaos of worry is relieved when I take zyprexa and im sure It would do the same on Clozapine.....clozapine is more nasty than zyprexa....the higher doses make you drool....and sit like a zombie and sleep, nasty stuff....
but yea....when zyprexa for me takes effect, it makes me sedated, yea...hypolethergic....wanting to stay in the bed, maybe the only thing to get up to do is to eat....
but the good thing about passiveness with people with schizophrenia is that there thoughts are relieved from repeated psychosis of either positive or negative....im not an expert at all...I just learned some of this doing research on the net....im not a human data base unfortunately lol....I would like to be one thought....that's my next goal haha
r
Posted by rjlockhart37 on May 10, 2013, at 0:02:02
In reply to Re: antipsychotic passiveness, posted by SLS on May 7, 2013, at 23:55:35
yea scott.....about a year ago I was at a NA meeting, this lady had been on a lot things for something....but she said she was put on thorazine and she feels free....
what makes me think, the dopamine is degregulated in something, then I think the APs clear it up....don't take this example at all the wrong way....but its like having a drink after a hard day....having anxiety, nerves are shot, then a couple shots of vodka, then it changes the mood....sometimes in activating ways and people get up and dance, or sedates them and makes then merry lol....but that's what im trying to say, APs maybe relieve unpleasant thoughts, and your able to do things without feeling negative, I read somewhere people with schizoaffective/phenia drink alcohol if there not medicated....
that's a crude example but that's a thing that made me think about the other day....
Posted by rjlockhart37 on May 10, 2013, at 0:10:05
In reply to Re: antipsychotic passiveness » rjlockhart37, posted by vbs on May 8, 2013, at 10:42:50
that's a strong regimen lol, if there all at the max doses, that's scary...that can cause Tartive Dynkenisa, when I was on 30mg zyprexa and Geodon 80mg when I was at the psych center....I would be talking and then I would jerk...like jerk, my jaw would shake in the middle of a sentence and it looked like I had hiccups....but It wasn't that...I think it was TD...because I felt restless all over my body, I can't describe what it felt like, but I felt like I had to jerk to stop feeling restless. I told the doctor there, she said it was anxiety and then increased the nuerontin, i hated it there....they force you take the medication....you have to act normal for them to release, that's what I did....anything to get out.
you should just try to stick with one AP and just max the dose....but im not a doctor.....if its working and keeps calm....yea....
Posted by Zyprexa on May 10, 2013, at 19:34:47
In reply to Re: antipsychotic passiveness, posted by rjlockhart37 on May 10, 2013, at 0:10:05
Thought you said the zyprexa is not doing anything?
Posted by rjlockhart37 on May 11, 2013, at 18:58:06
In reply to Re: antipsychotic passiveness » rjlockhart37, posted by Zyprexa on May 10, 2013, at 19:34:47
no, i put that sometimes it does not take effect, when i put it under the tongue it does take effect, but other times like 2 days ago....nothing, that's why im thinking it doesnt absorb fully into the blood stream, or something, it does once and a while, like the next day i wake up and feel gloomy and somewhat sedated, not really be excited about anythinng. That's kinda it.....but i posted this because when i first took zyprexa the first time it totally made me passive, and submissive to people....wierd...
but yea....right now i've just been praying to god about this issue to get it taken care of....its on the faith board.....
thanks for the post....
r
Posted by Zyprexa on May 14, 2013, at 19:35:04
In reply to Re: antipsychotic passiveness, posted by rjlockhart37 on May 11, 2013, at 18:58:06
Do you drink enough water? Maybe the pill does not fully disolve in your stomake. Not sure if I remember this correctly, but think that zyprexa is disolved in water. Maybe if you drink a lot of alcohol and not enough water it does not get absorbed properly. Wish some one could answer this.
Posted by Zyprexa on May 14, 2013, at 20:37:44
In reply to Re: antipsychotic passiveness, posted by rjlockhart37 on May 11, 2013, at 18:58:06
Some one told me the other day that an indian pharmacutical company, was being sued for putting out fake or not equivelent pills. Maybe your zyprexa is one of the drugs. I belive Aurobindo the maker of olanzapine is an indian manufacturer. Aurobindo olanzapine is the kind you described, small round yellow pill? I have some of that kind that were not working for me, I bought them a long while back maybe Nov. I switched to Teva olanzapine because it works better. I don't know maybe that is the problem? I've been meaning to research this more.
Posted by Lamdage22 on May 15, 2013, at 13:27:26
In reply to Re: antipsychotic passiveness, posted by Tomatheus on May 7, 2013, at 23:43:31
That might be ok to take for me speaking of restless akathisia.
Posted by Tomatheus on May 15, 2013, at 14:20:51
In reply to 5mg Abilify is enough? Tomateus?, posted by Lamdage22 on May 15, 2013, at 13:27:26
Lamdage22,
I would say that 5 mg of Abilify keeps my positive psychotic symptoms mostly under control. Does it completely eliminate my hallucinations and other perceptual disturbances? No. I still hear tapping, clicking, snapping, and popping sounds that others can't hear and get these thought-like "voices" that I like to call pseudohallucinations on 5 mg of Abilify. I also occasionally experience residual ideas of reference and very mild visual perceptual disturbances on 5 mg of Abilify, but my ideas of reference are for the most part under control at this dose of Abilify, and my sound hallucinations and pseudohallucinations are also much reduced.
As much as I'd like to have all of my positive psychotic symptoms eliminated, the cons of taking the amount of antipsychotic that would be required to eliminate all positive symptoms for me far outweigh the pros of doing so. I've tried taking higher doses of Abilify and other antipsychotics, and in most cases, my fatigue and hypersomnia became so severe that I was pretty much functionally useless. In the cases where this didn't happen (Seroquel and Geodon), my positive psychotic symptoms became much more severe right off the bat, prompting me to stop taking the medications.
It's my understanding that the amount of antipsychotic that's best for any individual with schizoaffective disorder, schizophrenia, or a related disorder isn't necessarily going to be the same that's best for another individual with the same disorder. Some individuals seem to require high doses, while others can get by with lower doses. Although I think it's possible that 5 mg of Abilify might be able to keep most of your psychotic symptoms under control, I wouldn't assume that it would just because that's the case for me. After all, if everybody with schizoaffective disorder responded to medications in the same way that I do, Seroquel and Geodon would be listed as medications to avoid because they worsen my psychotic symptoms.
Now, having said what I've said, maybe 5 mg of Abilify in combination with the Geodon that you're taking might be enough to suppress your psychotic symptoms. Although most individuals with schizoaffective disorder probably wouldn't find 5 mg of Abilify alone to be enough to keep their psychotic symptoms under control, I do think that taking 5 mg of Abilify *with* a moderate dose of Geodon might do the trick for many with the disorder.
But again, responses to antipsychotics, as with many medications, can be as unique as the individuals taking them. So, while taking 5 mg of Abilify with a moderate dose of Geodon might look good on paper, you really won't know how such a combo might affect you unless you try taking it.
T.
Posted by Lamdage22 on May 17, 2013, at 6:39:11
In reply to Re: 5mg Abilify is enough? Tomateus? » Lamdage22, posted by Tomatheus on May 15, 2013, at 14:20:51
That sounds good.
I feel the same way.. APs are a trade off. I dont feel that way about abilify though.
This is the end of the thread.
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