Psycho-Babble Medication Thread 1035691

Shown: posts 1 to 14 of 14. This is the beginning of the thread.

 

Switch from Effexor to Pristiq

Posted by In_denial on January 17, 2013, at 18:41:26

I would have posted this update on my thread from last month,but another babble user hijacked the thread.

I've seen many posts around the web saying that Effexor and Pristiq are chemically the same. Maybe they are, but they metabolize differently. I was a long time Effexor user. I've switched from 150mg Effexor to Pristiq 100 and the results have been amazing. I only had mild symptoms for a few days after cuttingi the Effexor cold turkey. Much more uplifting! I think ithe fact that Pristiq works more on noradrenalin than Effexor is what I needed. When I previously tried higher doses of Effexor, I got extreme dry mouth and trouble sleeping. Not so with the Pristiq. If Effexor has pooped out on anyone, don't let anyone talk you out of trying Pristiq.

 

Re: Switch from Effexor to Pristiq » In_denial

Posted by Phillipa on January 17, 2013, at 18:51:29

In reply to Switch from Effexor to Pristiq, posted by In_denial on January 17, 2013, at 18:41:26

So you like pristiq as my old pdoc took it also and liked it. What was different about it as once tried effexor thanks Phillipa

 

Re: Switch from Effexor to Pristiq

Posted by jono_in_adelaide on January 17, 2013, at 19:08:58

In reply to Switch from Effexor to Pristiq, posted by In_denial on January 17, 2013, at 18:41:26

Pristiq is the active metabolite of Effexor, so if you've taken Effexor, you've had Pristiq in your system - that is a long way from saying that they are the same, amitriptyline and nortriptyline have vastly different effects despite one being the metabolite of the other

Congratulations on finding somthing thats working for you

 

Re: Switch from Effexor to Pristiq

Posted by In_denial on January 17, 2013, at 19:28:30

In reply to Re: Switch from Effexor to Pristiq » In_denial, posted by Phillipa on January 17, 2013, at 18:51:29

Thank you! I think the biggest thing I noticed was that it almost completed lifted my brain fog.

 

Re: Switch from Effexor to Pristiq

Posted by SLS on January 17, 2013, at 23:10:24

In reply to Switch from Effexor to Pristiq, posted by In_denial on January 17, 2013, at 18:41:26

> I would have posted this update on my thread from last month,but another babble user hijacked the thread.
>
> I've seen many posts around the web saying that Effexor and Pristiq are chemically the same. Maybe they are, but they metabolize differently. I was a long time Effexor user. I've switched from 150mg Effexor to Pristiq 100 and the results have been amazing. I only had mild symptoms for a few days after cuttingi the Effexor cold turkey. Much more uplifting! I think ithe fact that Pristiq works more on noradrenalin than Effexor is what I needed. When I previously tried higher doses of Effexor, I got extreme dry mouth and trouble sleeping. Not so with the Pristiq. If Effexor has pooped out on anyone, don't let anyone talk you out of trying Pristiq.
>

Jono is very knowledgeable about psychopharmacology as his comparison of Effexor/Pristiq to amitriptyline/nortriptyine demonstrates. However, yours is not the first story I have come across describing an advantage of Pristiq over Effexor. However, I must mention that you should not have abandoned Effexor until a dosage of 300 mg/day was tried. I believe that 100 mg of Pristiq might be therapeutically equivalent to over 200 mg of Effexor. I would have to study the pharmacokinetics of Effexor, but not all Effexor becomes Pristiq in the body. A certain percentage will be metabolized into inactive substances, so, one would need to take a higher dosage of Effexor to approximate the levels reached by Pristiq. Also, we don't know the degree to which the Effexor molecule might actually interfere with the actions of the Pristiq molecule.

Messy.


- Scott

 

Re: Switch from Effexor to Pristiq

Posted by schleprock on January 17, 2013, at 23:59:38

In reply to Switch from Effexor to Pristiq, posted by In_denial on January 17, 2013, at 18:41:26

Guys usually go for Effexor. Women seem to prefer Pristiq. Depends on which one you are.

 

Re: Switch from Effexor to Pristiq » schleprock

Posted by SLS on January 18, 2013, at 6:34:04

In reply to Re: Switch from Effexor to Pristiq, posted by schleprock on January 17, 2013, at 23:59:38

> Guys usually go for Effexor. Women seem to prefer Pristiq. Depends on which one you are.

Hmm.

How do you know this?

I don't discount that this is possible. Males tend to be better tricyclic responders than females.


- Scott

 

Re: Switch from Effexor to Pristiq » SLS

Posted by Phillipa on January 18, 2013, at 10:20:04

In reply to Re: Switch from Effexor to Pristiq » schleprock, posted by SLS on January 18, 2013, at 6:34:04

They are? Is there a reason? Phillipa

 

Re: Switch from Effexor to Pristiq

Posted by SLS on January 18, 2013, at 10:59:12

In reply to Re: Switch from Effexor to Pristiq » SLS, posted by Phillipa on January 18, 2013, at 10:20:04

> They are? Is there a reason? Phillipa

I am absolutely sure that there is a reason. I just don't know what it is.

:-)


- Scott

 

Re: Switch from Effexor to Pristiq » SLS

Posted by schleprock on January 18, 2013, at 15:46:27

In reply to Re: Switch from Effexor to Pristiq » schleprock, posted by SLS on January 18, 2013, at 6:34:04

> > Guys usually go for Effexor. Women seem to prefer Pristiq. Depends on which one you are.
>
> Hmm.
>
> How do you know this?
>
> I don't discount that this is possible. Males tend to be better tricyclic responders than females.
>
>
> - Scott

"Pristiq" is a very feminine sounding name. While "Effexor" is more masculine. If they were companies, Pristiq would be a high-fashion line of clothing. Effexor would be a manufacturer of power tools and stuff. I would think this would be obvious.

 

Re: Switch from Effexor to Pristiq

Posted by In_denial on January 18, 2013, at 21:25:10

In reply to Re: Switch from Effexor to Pristiq » SLS, posted by schleprock on January 18, 2013, at 15:46:27

I agree that Pristiq is a prissy sounding name. Sounds like a birth control pill or something. I am a male. I did take Effexor up to 300 mg. The side effects were horrible. I think I've read that Pristiq's effect on noradrenalin is many times stronger than that of Effexor. The doc told me that the 100mg Pristiq is approximate to 300mg Effexor but without the side effects. He was right in my case. I think it's effect on serotonin to noradrenalin ratio is what I needed.

 

Re: Switch from Effexor to Pristiq » schleprock

Posted by SLS on January 18, 2013, at 22:40:34

In reply to Re: Switch from Effexor to Pristiq » SLS, posted by schleprock on January 18, 2013, at 15:46:27

> > > Guys usually go for Effexor. Women seem to prefer Pristiq. Depends on which one you are.
> >
> > Hmm.
> >
> > How do you know this?
> >
> > I don't discount that this is possible. Males tend to be better tricyclic responders than females.
> >
> >
> > - Scott
>
> "Pristiq" is a very feminine sounding name. While "Effexor" is more masculine. If they were companies, Pristiq would be a high-fashion line of clothing. Effexor would be a manufacturer of power tools and stuff. I would think this would be obvious.


I had thought that this is what you meant, but I wasn't sure.

:-)


- Scott

 

Re: Switch from Effexor to Pristiq » In_denial

Posted by SLS on January 18, 2013, at 22:43:24

In reply to Re: Switch from Effexor to Pristiq, posted by In_denial on January 18, 2013, at 21:25:10

> I did take Effexor up to 300 mg. The side effects were horrible. I think I've read that Pristiq's effect on noradrenalin is many times stronger than that of Effexor. The doc told me that the 100mg Pristiq is approximate to 300mg Effexor but without the side effects. He was right in my case.


Thanks for sharing this. Good to know.


- Scott

 

Re: Switch from Effexor to Pristiq

Posted by jono_in_adelaide on January 20, 2013, at 17:47:18

In reply to Re: Switch from Effexor to Pristiq, posted by SLS on January 17, 2013, at 23:10:24

Totaly agree Scott, when i hear doctors saying that efexor and pristiq are the same, it gets on my nerves, they arnt the same, they might be similar, but there are important differences.

> > I would have posted this update on my thread from last month,but another babble user hijacked the thread.
> >
> > I've seen many posts around the web saying that Effexor and Pristiq are chemically the same. Maybe they are, but they metabolize differently. I was a long time Effexor user. I've switched from 150mg Effexor to Pristiq 100 and the results have been amazing. I only had mild symptoms for a few days after cuttingi the Effexor cold turkey. Much more uplifting! I think ithe fact that Pristiq works more on noradrenalin than Effexor is what I needed. When I previously tried higher doses of Effexor, I got extreme dry mouth and trouble sleeping. Not so with the Pristiq. If Effexor has pooped out on anyone, don't let anyone talk you out of trying Pristiq.
> >
>
> Jono is very knowledgeable about psychopharmacology as his comparison of Effexor/Pristiq to amitriptyline/nortriptyine demonstrates. However, yours is not the first story I have come across describing an advantage of Pristiq over Effexor. However, I must mention that you should not have abandoned Effexor until a dosage of 300 mg/day was tried. I believe that 100 mg of Pristiq might be therapeutically equivalent to over 200 mg of Effexor. I would have to study the pharmacokinetics of Effexor, but not all Effexor becomes Pristiq in the body. A certain percentage will be metabolized into inactive substances, so, one would need to take a higher dosage of Effexor to approximate the levels reached by Pristiq. Also, we don't know the degree to which the Effexor molecule might actually interfere with the actions of the Pristiq molecule.
>
> Messy.
>
>
> - Scott


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