Psycho-Babble Medication Thread 1024656

Shown: posts 1 to 25 of 27. This is the beginning of the thread.

 

Monocycline, ECT and cycling

Posted by Slabicki on September 1, 2012, at 17:11:57

Hello,

I just got Monocycline prescription this morning,
and I was so happy. My doctor is wonderful!!!
However, I deal with the difficult issue right now.
I still experience mood swings or what's called - rapid cycling. My mood changes on average every 5-8 hours.
I was never bipolar. This is due to taking Ketaconazole about 2 months ago.
That's why I'm concerned to try Minocycline at the moment.
My main concern is that it can increase the anxiety when I'm in anxiety mode.
I think would it be wise to try ECT first to see if the cycling stops?
Then treat depression with Minocycline.
That's what I think I should do.
It's a difficult decision, and I wish I could avoid ECT.
I'm just posting this because I'm so frustrated right now.
I will welcome others opinions.

Slabicki

 

Re: Monocycline, ECT and cycling » Slabicki

Posted by Phillipa on September 1, 2012, at 19:22:40

In reply to Monocycline, ECT and cycling, posted by Slabicki on September 1, 2012, at 17:11:57

Any of these meds were you on at the time? As it says depression is a side effect? Phillipa

http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000780/

 

Re: Monocycline, ECT and cycling » Slabicki

Posted by SLS on September 1, 2012, at 20:28:08

In reply to Monocycline, ECT and cycling, posted by Slabicki on September 1, 2012, at 17:11:57

Lamictal might be an ideal drug to add to your regime right now. It can help reduce rapid cyclicity, and is supposed to work in tandem with minocycline to reduce glutamate overactivity.


- Scott

 

Re: Monocycline, ECT and cycling » Slabicki

Posted by brynb on September 2, 2012, at 16:30:44

In reply to Monocycline, ECT and cycling, posted by Slabicki on September 1, 2012, at 17:11:57

Hi Slabicki,

What's your current med combo? During my last depressive episode, I started taking Tramadol (for pain) and it actually got me out of bed and basically helped me out of a two month (or so) funk.
It works fast (as in within an hour of taking the first dose). I take it in addition to Lithium and Lexapro.

Good luck...

-b

 

Re: Monocycline, ECT and cycling

Posted by Slabicki on September 2, 2012, at 23:57:49

In reply to Re: Monocycline, ECT and cycling » Slabicki, posted by brynb on September 2, 2012, at 16:30:44

Hi everybody,

Minocycline and ECT are my only choices at the moment. I have also Atenolol 25 mg for anxiety - haven,t tried it yet.
Today I was in the anxiety mode for most of my day, and about 3 hours depressive mode.
I'm so confused right now.
I wish I could go back to my normal condition.
I wonder right now should I even consider ECT
if anxiety continues.
It's such a difficult decision, because I can't
predict my body's response.
I guess i will watch my symptoms and go from there.

Slabicki

 

Re: Monocycline, ECT and cycling » Slabicki

Posted by SLS on September 3, 2012, at 0:33:46

In reply to Re: Monocycline, ECT and cycling, posted by Slabicki on September 2, 2012, at 23:57:49

> Hi everybody,
>
> Minocycline and ECT are my only choices at the moment. I have also Atenolol 25 mg for anxiety - haven,t tried it yet.
> Today I was in the anxiety mode for most of my day, and about 3 hours depressive mode.
> I'm so confused right now.
> I wish I could go back to my normal condition.
> I wonder right now should I even consider ECT
> if anxiety continues.
> It's such a difficult decision, because I can't
> predict my body's response.
> I guess i will watch my symptoms and go from there.


My initial reaction to the prospect of your undergoing ECT is one of trepidation. Why was ECT ever considered as an alternative treatment? What is it about your case that your doctor says is treatable using ECT? What is the rationale? I have heard it proposed to use ECT for anxiety disorders, but I have not seen any science to support this notion. ECT is sometimes used for treating acute medication-resitant mania, so its utility does go beyond depressive episodes. However, it does not appear to be effective for anxiety disorders or OCD. Interestingly, of all people, Max Fink suggested in 1982 that ECT was bad idea for anxiety disorders.

http://www.ncbi.nlm.nih.gov/pubmed/7149085

Why are you interested in minocycline? What is the rationale for using it in your case? What other drugs would you take along with it?


- Scott


 

Re: Monocycline, ECT and cycling SLS

Posted by Slabicki on September 3, 2012, at 13:19:05

In reply to Re: Monocycline, ECT and cycling » Slabicki, posted by SLS on September 3, 2012, at 0:33:46

Hi Scott,

I appreciate your input.

I just want to let you know that I'm aware that ECT isn't affective for anxiety. However, there is a scientific evidence that it may be effective
for rapid cycling. I don't have a link available
at the moment, but I've done some research.

It all started with a bad depression and mood swings due to use of Ketaconazole. The anxiety and some kind of overstimulation started so unexpectadely.

I'm under the exellent medical care. It takes two doctors to get the ECT approval.
I would't use Minocycline at the moment.
And I wouldn't do anything foolish to make myself
worse.

I'm posting here because I want to share my experience and get other people's opinions.

I realize that my case is complicated right now.
I used to suffer in the past from the pure depression.

I know that I have to stay positive.
I hope to get rid of my symptoms and return to work some time in the future.

Slabicki

 

Re: Monocycline, ECT and cycling SLS » Slabicki

Posted by SLS on September 3, 2012, at 14:35:34

In reply to Re: Monocycline, ECT and cycling SLS, posted by Slabicki on September 3, 2012, at 13:19:05

> However, there is a scientific evidence that it may be effective
> for rapid cycling.

Good to know!

> I'm posting here because I want to share my experience and get other people's opinions.

My course of ECT was a failure. I went for 6 unilateral left followed by 9 bilateral. I was disoriented for over a month. Roads that I had travelled down my whole life became unfamiliar to me. Driving became an adventure.

What type of ECT are you getting?


- Scott

 

Re: Monocycline, ECT and cycling SLS

Posted by emmanuel98 on September 3, 2012, at 19:03:34

In reply to Re: Monocycline, ECT and cycling SLS » Slabicki, posted by SLS on September 3, 2012, at 14:35:34

I also had 9 bilateral ECT sessions and for about a month afterwards, I could not remember neighbor's names, names of people I had been acquainted with for a long time, how to get from point A to point B. Names of major roads, locations of stores. Somehow I drove myself places but I could not have explained how I got there, since I didn't know the names of the roads. I just seemed to go on auto-pilot. This would all have been worth it had the ECT helped at all (I was suicidal and severely depressed), but it didn't. Also, the experience of ECT is horrible. YOu wake up disoriented and sick and with a severe headache. It takes hours to recover. Bilateral ECT is the worst and almost has to be done inpatient because the disorientation is so bad and lasts so long. When I had bilateral ECT, people came to visit me in the hospital and I have no memory of it whatsoever.

 

Re: Monocycline, ECT and cycling SLS

Posted by Slabicki on September 3, 2012, at 21:35:52

In reply to Re: Monocycline, ECT and cycling » Slabicki, posted by SLS on September 3, 2012, at 0:33:46

Hi Scott,

I just want to say that you made me concerned about anxiety and ECT.
What do you think can happen?
can I get the anxiety attack or the increase in anxiety?

I'm under good medical care. I've posted more informations this morning, but somehow my post
didn't go through.

Slabicki

 

Re: Monocycline, ECT and cycling SLS » Slabicki

Posted by SLS on September 3, 2012, at 21:50:23

In reply to Re: Monocycline, ECT and cycling SLS, posted by Slabicki on September 3, 2012, at 21:35:52

> I just want to say that you made me concerned about anxiety and ECT.

ECT should not make anxiety disorders worse. It just won't make them better. However, if the anxiety is really a symptom of depression, I would expect it to improve as the depression improves.


- Scott

 

Re: Monocycline, ECT and cycling » Slabicki

Posted by phidippus on September 3, 2012, at 22:42:08

In reply to Monocycline, ECT and cycling, posted by Slabicki on September 1, 2012, at 17:11:57

If your cycling, you need a mood stabilizer.

I don't know that the minocycline is a good idea. It might make you cycle worse.

If you do ECT the cycling will stop, then slowly start again unless you take a mood stabilizer.

Eric

 

Re: Monocycline, ECT and cycling » phidippus

Posted by SLS on September 3, 2012, at 23:14:33

In reply to Re: Monocycline, ECT and cycling » Slabicki, posted by phidippus on September 3, 2012, at 22:42:08

> I don't know that the minocycline is a good idea. It might make you cycle worse.

You could be right, but what are your reasons for saying this?

Is there one mechanism in particular that you cite as potentially exacerbating rapid cycling?

I haven't seen any mention of this in the literature yet, and I don't know any anecdotes reporting this.


- Scott

 

Re: Monocycline, ECT and cycling » SLS

Posted by phidippus on September 3, 2012, at 23:45:30

In reply to Re: Monocycline, ECT and cycling » phidippus, posted by SLS on September 3, 2012, at 23:14:33

From the literature I've read, the term 'mental changes' comes up a lot. That kind of raises a red flag for me.

There is no one mechanism of action that seems like it would induce potential, uh? Mania.

Eric

 

Re: Monocycline, ECT and cycling » phidippus

Posted by Emme_v2 on September 4, 2012, at 5:41:57

In reply to Re: Monocycline, ECT and cycling » SLS, posted by phidippus on September 3, 2012, at 23:45:30

> From the literature I've read, the term 'mental changes' comes up a lot. That kind of raises a red flag for me.
>
> There is no one mechanism of action that seems like it would induce potential, uh? Mania.
>
> Eric
>
>

At least one clinical trial is recruiting participants to study minocycline as a treatment for bipolar depression.

http://clinicaltrials.gov/ct2/show/NCT01514422

It seems, therefore, that researchers consider it promising for bipolar patients.

 

Re: Monocycline, ECT and cycling » phidippus

Posted by SLS on September 4, 2012, at 6:22:52

In reply to Re: Monocycline, ECT and cycling » SLS, posted by phidippus on September 3, 2012, at 23:45:30

> From the literature I've read, the term 'mental changes' comes up a lot. That kind of raises a red flag for me.

The remission of depression is also a mental change.

My doctor says that any drug that is capable of producing an antidepressant effect is capable of precipitating mania. I guess we shall see.


- Scott

 

Re: Monocycline, ECT and cycling

Posted by Hugh on September 4, 2012, at 12:42:44

In reply to Re: Monocycline, ECT and cycling » phidippus, posted by Emme_v2 on September 4, 2012, at 5:41:57

> At least one clinical trial is recruiting participants to study minocycline as a treatment for bipolar depression.
>
> http://clinicaltrials.gov/ct2/show/NCT01514422
>
> It seems, therefore, that researchers consider it promising for bipolar patients.

At least two clinical trials: http://clinicaltrials.gov/ct2/show/NCT01429272

 

Re: Terminating my thread at the moment!

Posted by Slabicki on September 4, 2012, at 14:27:41

In reply to Re: Monocycline, ECT and cycling, posted by Hugh on September 4, 2012, at 12:42:44

Hello,

I'm considering this side as totally confidential!
We are posting here anonymously.
I never go public with my problems.
I'm sorry I can't provide any further explanations
at the moment.

Slabicki

 

Re: Terminating my thread at the moment! » Slabicki

Posted by SLS on September 4, 2012, at 15:36:02

In reply to Re: Terminating my thread at the moment!, posted by Slabicki on September 4, 2012, at 14:27:41

> Hello,
>
> I'm considering this side as totally confidential!
> We are posting here anonymously.
> I never go public with my problems.
> I'm sorry I can't provide any further explanations
> at the moment.
>
> Slabicki


I am very disappointed that you are leaving this thread. But I can certainly understand if you feel there was a breach in confidentiality. I hope this doesn't dissuade you from posting on Psycho-Babble any more.

Be well.


- Scott

 

Re: Monocycline, ECT and cycling » Hugh

Posted by phidippus on September 4, 2012, at 16:13:40

In reply to Re: Monocycline, ECT and cycling, posted by Hugh on September 4, 2012, at 12:42:44

Impportant to note is that Participants must be on a mood stabilizer medication for at least two weeks prior to starting the study, and must remain on the treatment during the study

Eric

 

Re: Monocycline, ECT and cycling » Emme_v2

Posted by phidippus on September 4, 2012, at 16:23:39

In reply to Re: Monocycline, ECT and cycling » phidippus, posted by Emme_v2 on September 4, 2012, at 5:41:57

Its important to note that participants must be on mood stabilizer medication for at least two weeks prior to starting the study, and must remain on the treatment during the study.

I wonder if they are worried about inducing an unstable mood.

Eric

 

Re: Monocycline, ECT and cycling » phidippus

Posted by SLS on September 4, 2012, at 18:34:53

In reply to Re: Monocycline, ECT and cycling » Emme_v2, posted by phidippus on September 4, 2012, at 16:23:39

> Its important to note that participants must be on mood stabilizer medication for at least two weeks prior to starting the study, and must remain on the treatment during the study.
>
> I wonder if they are worried about inducing an unstable mood.
>
> Eric


Perhaps in bipolar patients. However, there is a clinical trial assessing the efficacy of minocycline in the treatment of unipolar depression. Mood stabilizers are not required.

http://clinicaltrials.gov/ct2/show/NCT01574742


- Scott

 

Re: Monocycline, ECT and cycling » phidippus

Posted by Emme_v2 on September 4, 2012, at 20:02:20

In reply to Re: Monocycline, ECT and cycling » Emme_v2, posted by phidippus on September 4, 2012, at 16:23:39

> Its important to note that participants must be on mood stabilizer medication for at least two weeks prior to starting the study, and must remain on the treatment during the study.
>
> I wonder if they are worried about inducing an unstable mood.
>
> Eric

Good question. Perhaps they expect the minocycline to help with the depressive side of bipolar and want to make sure there is protection for the manic side.

 

Re: Monocycline, ECT and cycling

Posted by Phillipa on September 4, 2012, at 20:25:27

In reply to Re: Monocycline, ECT and cycling » phidippus, posted by Emme_v2 on September 4, 2012, at 20:02:20

I guess it's not good for those with long term anxiety. What about when using for antibiotic purposes the lupus syndrome which takes a year to disappear after discontinuation, the darkening of skin and nails? The headaches & dizziness. Seems the dermatologists are very aware of these as side effects. I also read a link where thyroid was involved? Phillipa

 

Re: Monocycline, ECT and cycling » Phillipa

Posted by SLS on September 4, 2012, at 23:25:28

In reply to Re: Monocycline, ECT and cycling, posted by Phillipa on September 4, 2012, at 20:25:27

> I guess it's not good for those with long term anxiety. What about when using for antibiotic purposes the lupus syndrome which takes a year to disappear after discontinuation, the darkening of skin and nails? The headaches & dizziness. Seems the dermatologists are very aware of these as side effects. I also read a link where thyroid was involved? Phillipa

The side effects listed are worrisome. They always are. It would be an irony if one must become blue to not be blue.

http://www.rxlist.com/minocin-capsules-drug/side-effects-interactions.htm

- Scott


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