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Dr. Bob is Robert Hsiung, MD,
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Posted by starbells on August 28, 2012, at 14:06:51
hi,,,im new to this site, ive been on depnil(the south african name) the maoi anti-depressant for about a year. was great ,i was on 600 mg. i felt it relaxed me. but then it changed and gave me an awful heated anxiety in my stomach when i take it. now on 450 mg and want to go off. when i do cut down i go INTO a depression and its dangerouse i think going off re: depression. so i am stuck. any ideas ? thanks;)
Posted by jono_in_adelaide on August 28, 2012, at 23:22:32
In reply to COMING OFF DEPNIL, posted by starbells on August 28, 2012, at 14:06:51
Could you switch to a different antidepressant, such as an SSRI or mirtazapine?
Posted by SLS on August 29, 2012, at 4:32:32
In reply to COMING OFF DEPNIL, posted by starbells on August 28, 2012, at 14:06:51
> hi,,,im new to this site, ive been on depnil(the south african name) the maoi anti-depressant for about a year. was great ,i was on 600 mg. i felt it relaxed me. but then it changed and gave me an awful heated anxiety in my stomach when i take it. now on 450 mg and want to go off. when i do cut down i go INTO a depression and its dangerouse i think going off re: depression. so i am stuck. any ideas ? thanks;)
According to your doctors, how long would you have to wait to try another antidepressant? It might help to use another drug as a "bridge" between treatments. I would consider using olanzapine (Zyprexa) temporarily during the waiting period and until the new drugs exert their therapeutic effects. Otherwise, you might feel terrible for weeks or months. If you responded to moclobemide, you might respond even better to Nardil. However, I would probably look at other untried treatments first. What have you tried so far?
Moclobemide is reversible, but it still relatively "sticky". I don't know how much time is necessary to wait. It might be only a few days.
Good luck.
- Scott
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