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Dr. Bob is Robert Hsiung, MD,
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Posted by Sheilac on May 26, 2012, at 17:41:05
I can feel when Adderall wears off so I know it doesn't stay in my body long. But how long does Wellbutrin stay in the body? Is it similar to Adderall?
I was wondering if they are pretty much interchangeable for ADD and depression?
Posted by Christ_empowered on May 26, 2012, at 18:56:08
In reply to Adderall vs Wellbutrin, posted by Sheilac on May 26, 2012, at 17:41:05
Adderall is more effective for ADD/ADHD than wellbutrin. Depression...I dunno. Most AD drugs aren't that great, anyway, so I can't imagine amphetamines being any less effective.
Posted by psychobot5000 on May 29, 2012, at 1:31:00
In reply to Adderall vs Wellbutrin, posted by Sheilac on May 26, 2012, at 17:41:05
> I can feel when Adderall wears off so I know it doesn't stay in my body long. But how long does Wellbutrin stay in the body? Is it similar to Adderall?
>
> I was wondering if they are pretty much interchangeable for ADD and depression?
>
>For whatever reason, the two drugs function differently, even though they look sort of similar when you check what sort of neurotransmitters they affect. Amphetamines are psychostimulants--which provide immediate positive effect for mood and concentration, but don't have lasting effects. Wellbutrin is more of an antidepressant. Its immediate effects aren't as remarkable, but down the line it can provide more mood benefit. It's not immediate, though. It takes at least a few days.
Or, shorter: adderall will provide more ADD benefit, but wellbutrin may provide more mood/depression benefit. However, both affect both categories. And adderall's mood benefits are immediate, whereas wellbutrin's take a while, but may well be stronger.
For what it's worth, adderall almost certainly stays in your body after the effect 'wears off.' The wearing off has as much to do with your body adjusting as anything else. Amphetamine's half-life is about 11 hours, usually.
That said, wellbutrin has a shorter blood half-life, if I remember right. So its positive effect on concentration may last less long.
You might consider (possibly small) doses of desipramine or protriptyline. They can also help with depression and ADHD, and they both last longer than wellbutrin.
Posted by sheilac on May 30, 2012, at 10:49:43
In reply to Re: Adderall vs Wellbutrin, posted by psychobot5000 on May 29, 2012, at 1:31:00
I notice the fall out of the Adderall in the afternoon and it is not good. I get irritable, edgy and angry when the Adderall wears off.
I don't notice the super concentration abilities with Wellbutrin that I do with Adderall, but I do notice a little better concentration and motivation abilities with Wellbutrin.
I love Adderall - I feel like I get a lot done and I have super cocentration and motivation, but the come down from Adderall is hell.
I don't notice any come down effect from Wellbutrin, which is great. It does't have the super concentration and motivation ability that Adderall has, but as least I'm not a witch later in the day.
For now I will stick with Wellbutin.
Posted by creepy on June 7, 2012, at 7:13:33
In reply to Adderall vs Wellbutrin, posted by Sheilac on May 26, 2012, at 17:41:05
for me wellbutrin worked as an AD for a few months then went poof.
It doesnt help concentration like a stimulant does.
The IR version is about 4 hours. SR is about 8. XL is 12 or so.
Posted by phidippus on June 7, 2012, at 19:59:34
In reply to Adderall vs Wellbutrin, posted by Sheilac on May 26, 2012, at 17:41:05
Wellbutrin can be taken to treat both the symptoms of ADHD and depression.
Wellbutrin is a drug that is taken daily and accumulates in your system. It doesn't matter what the half-life is.
Wellbutrin is not similar to Adderal, it is in a class of drugs referred to as an NDRI (norepinephrine-dopamine reuptake inhibitor). It is not a stimulant.
Eric
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